Abstract: The invention relates to a process for solution-phase synthesis of D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide, an active ingredient used for both common and rare diseases including a mitochondrial targeted therapy for ischemia reperfusion injury.

Abstract: The invention relates to a process for solution-phase synthesis of D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide, an active ingredient used for both common and rare diseases including a mitochondrial targeted therapy for ischemia reperfusion injury.

Abstract: The invention relates to a process for solution-phase synthesis of D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide, an active ingredient used for both common and rare diseases including a mitochondrial targeted therapy for ischemia reperfusion injury.

Abstract: The invention relates to a process for solution-phase synthesis of D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide, an active ingredient used for both common and rare diseases including a mitochondrial targeted therapy for ischemia reperfusion injury.

Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is a selective late sodium current inhibitor. The disclosure also provides compounds that are synthetic intermediates.

Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is a selective late sodium current inhibitor. The disclosure also provides compounds that are synthetic intermediates.

Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is a selective late sodium current inhibitor. The disclosure also provides compounds that are synthetic intermediates.

Abstract: An industrial purification process for preparing a highly pure and free flowing solid of 7-ethyltryptophol. Crude 7-ethyltryptophol, prepared by, known procedures is dissolved in an organic solvent and washed with aqueous acid solution to form an aqueous phase and an organic phase. After at least partially removing the solvent from the organic phase, it is triturated with an alkane solvent under cooling to solidify the residue. A highly pure and free-flowing solid of 7-ethyltryptophol is recovered therefrom.

Abstract: Polymeric organic coating for electroluminescent lamp components, particularly for phosphor particles and electrodes and a method of making same, wherein the polymer is formed using an initiator, preferably by ring-opening metathesis polymerization. A dense hydrophobic organic coating is formed which is capable of protecting the electroluminescent device components from exogenous agents such as moisture and eventual degradation. The polymer layer may be attached to an outer surface of the component by one or more tethering layers.

Abstract: Polymeric organic coating for electroluminescent lamp components, particularly for phosphor particles and electrodes and a method of making same, wherein the polymer is formed using an initiator, preferably by ring-opening metathesis polymerization. A dense hydrophobic organic coating is formed which is capable of protecting the electroluminescent device components from exogenous agents such as moisture and eventual degradation. The polymer layer may be attached to an outer surface of the component by one or more tethering layers.

Abstract: The present invention provides new catalyst formats which comprise a supported catalyst tethered to a second and different catalyst by a suitable tethering ligand. A preferred system comprises a heterogeneous supported metal catalyst tethered to a homogeneous catalyst. This combination of homogeneous and heterogeneous catalysts has a sufficient lifetime and unusually high catalytic activity in arene hydrogenations, and potentially many other reactions as well, including, but not limited to hydroformylation, hydrosilation, olefin oxidation, isomerization, hydrocyanation, olefin metathesis, olefin polymerization, carbonylation, enantioselective catalysis and photoduplication. These catalysts are easily separated from the products, and can be reused repeatedly, making these systems very economical.