Patents by Inventor Hans AERNI

Hans AERNI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS RELATED TO TUMOR ACTIVATED ANTIBODIES TARGETING PSMA AND EFFECTOR CELL ANTIGENS
    Publication number: 20240059790
    Abstract: Described herein are compositions and formulations comprising a recombinant polypeptide. Related methods and uses of these compositions and formulations are also described herein.
    Type: Application
    Filed: May 8, 2023
    Publication date: February 22, 2024
    Inventors: David CAMPBELL, Thomas R. DIRAIMONDO, Carolina CAFFARO, Hans AERNI
  • INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF
    Publication number: 20240043823
    Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
    Type: Application
    Filed: October 4, 2023
    Publication date: February 8, 2024
    Applicants: Synthorx, Inc., The Scripps Research Institute
    Inventors: Jerod PTACIN, Carolina CAFFARO, Hans AERNI, Yorke ZHANG, Emil C. FISCHER, Aaron W. FELDMAN, Vivian T. DIEN, Floyd E. ROMESBERG
  • Incorporation of unnatural nucleotides and methods thereof
    Patent number: 11834689
    Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: December 5, 2023
    Assignees: THE SCRIPPS RESEARCH INSTITUTE, SYNTHORX, INC.
    Inventors: Jerod Ptacin, Carolina Caffaro, Hans Aerni, Yorke Zhang, Emil C. Fischer, Aaron W. Feldman, Vivian T. Dien, Floyd E. Romesberg
  • METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE
    Publication number: 20220324792
    Abstract: Disclosed herein are methods of preparing N6-((2-azidoethoxy)carbonyl)lysine, N6-((2-azidoethoxy)carbonyl)-L-lysine, and N6-((2-azidoethoxy)carbonyl)-D-lysine. Also disclosed herein are the compounds tert-butyl N2-(tert-butoxycarbonyl)-N6-((2-chloroethoxy)carbonyl)-L-lysinate and tert-butyl N6-((2-azidoethoxy)carbonyl)-N2-(tert-butoxycarbonyl)-L-lysinate, and uses thereof.
    Type: Application
    Filed: June 21, 2022
    Publication date: October 13, 2022
    Applicant: Synthorx, Inc.
    Inventors: Hans AERNI, Randall SCHEUERMAN, Nikolai F. SEPETOV, Alexander V. SHIROKOV
  • INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF
    Publication number: 20210222147
    Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
    Type: Application
    Filed: March 9, 2021
    Publication date: July 22, 2021
    Inventors: Jerod PTACIN, Carolina CAFFARO, Hans AERNI, Yorke ZHANG, Emil C. FISCHER, Aaron W. FELDMAN, Vivian T. DIEN, Floyd E. ROMESBERG
  • INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF
    Publication number: 20200131555
    Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
    Type: Application
    Filed: July 10, 2018
    Publication date: April 30, 2020
    Inventors: Jerod PTACIN, Carolina CAFFARO, Hans AERNI, Yorke ZHANG, Emil C. FISCHER, Aaron W. FELDMAN, Vivian T. DIEN, Floyd E. ROMESBERG
  • INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF
    Publication number: 20190376054
    Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
    Type: Application
    Filed: August 2, 2019
    Publication date: December 12, 2019
    Inventors: Jerod PTACIN, Carolina CAFFARO, Hans AERNI, Yorke ZHANG, Emil C. FISCHER, Aaron W. FELDMAN, Vivian T. DIEN, Floyd E. ROMESBERG