Patents by Inventor Hans Bardonner

Hans Bardonner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5023379
    Abstract: A process for the production of hydroxyamines of the formula IR.sup.1 --CH(OH)--CH(NHR.sup.3)--R.sup.2 (I)whereinR.sup.1 and R.sup.2 independently of one another are H or CH.sub.2 OH andR.sup.3 is H, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -hydroxyalkyl comprising reacting an oxo compound with an amine and reducing the resultant ketimine with a reducing agent.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: June 11, 1991
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Ernst Felder, Michael Romer, Hans Bardonner, Hartmut Hartner, Wolfgang Fruhstorfer
  • Patent number: 4605794
    Abstract: A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree. C., a bulk density of 0.3-0.6 g/ml, a .gamma.-sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7-1.5 m.sup.2 /g, a bending strength of at least 7 N/mm.sup.2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree. C., and spray-drying this solution at a temperature of 140.degree. to 170.degree. C. The sorbitol thus obtained has a water content of less than 1%.The sorbitol is useful for the production of compressed formulations.
    Type: Grant
    Filed: January 23, 1985
    Date of Patent: August 12, 1986
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Friedrich Reiff, Hartmut Hartner, Arno Basedow, Hans-Wolfgang Hugenbusch, Peter C. Schmidt, Hans Bardonner
  • Patent number: 4507511
    Abstract: A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree. C., a bulk density of 0.3-0.6 g/ml, a .gamma.-sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7-1.5 m.sup.2 /g, a bending strength of at least 7 N/mm.sup.2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree. C., and spray-drying this solution at a temperature of 140.degree. to 170.degree. C. The sorbitol thus obtained has a water content of less than 1%.The sorbitol is useful for the production of compressed formulations.
    Type: Grant
    Filed: December 7, 1983
    Date of Patent: March 26, 1985
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Friedrich Reiff, Hartmut Hartner, Arno Basedow, Hans-Wolfgang Hugenbusch, Peter C. Schmidt, Hans Bardonner
  • Patent number: 4474987
    Abstract: A process for preparing an N,N-disubstituted p-phenylenediamine of the formula ##STR1## wherein R.sup.1 is alkyl of 1-6 C atoms, R.sup.2 is alkyl of 1-6 C atoms or alkyl of 1-6 C atoms which is substituted by OH, lower alkoxy, a sulfo group or an alkylsulfonamido group and R.sup.3 is hydrogen or lower alkylor an acid addition salt thereof,comprises adding an alkyl nitrite, as a nitrosation agent,to an aqueous, acid suspension of the corresponding aniline derivative of the formula ##STR2## thereby forming the corresponding N,N-disubstituted p-nitroso-aniline, and subsequently hydrogenating the latter without isolation thereof from the reaction mixture.
    Type: Grant
    Filed: April 5, 1982
    Date of Patent: October 2, 1984
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Bruno Wollemann, Hartmut Hartner, Hans Bardonner