Abstract: The present invention relates to new S-(carbamoylphenylselenyl) derivatives of glutathione and of .alpha.

Abstract: The present invention relates to new O-alkyl-O-carbamoylglycerophosphocholines of the general formulae I or II ##STR1## and processes for treating human beings suffering from diseases caused by hypertension by administering one or several of the above compounds.

Abstract: Aqueous phospholipid solutions and their preparations, consisting of phospholipids and a solution promoter of the general formula CH.sub.3 (CH.sub.2).sub.n CONHCH.sub.2 CH.sub.2 OH, in which n is 3, 4 or 5.

Abstract: The present invention is related to new indol acetic acid derivatives having the general formula ##STR1## the salts thereof, processes for producing the same and pharmaceutical preparations comprising the same as well as their use as drugs having antithrombotic, antiarteriosclerotic and antiphlogistic activity.

Abstract: The present invention refers to new .omega.-(2-oxo-benzazolinyl)-alkanoic acids as well as salts and esters thereof having the general formula I ##STR1## and having antiinflammatory, analgesic and antithrombotic activity.

Abstract: The present invention refers to N-substituted .omega.-(2-oxo-4-imidazolin-1-yl) alcanoic acids as well as salts and esters thereof having the general formula I ##STR1## The compounds are useful, for example, as antiallergics, antiasthmatics, etc.

Abstract: The present invention refers to new 5-(N-Alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives having the general formula I ##STR1##

Abstract: 2-Oxo-1-pyrrolidinylalkylcarboxylic acid amides of formula I ##STR1## in which R represents a hydrogen atom or hydroxy group, R.sub.1 represents a hydrogen atom or a methyl group and R.sub.2 represents a substituted or unsubstituted pyridyl group or a substituted phenyl group, the substitution being by from 1 to 3 substituents, which may be the same or different selected from halogen atoms, trifluoromethyl, nitro and acetyl groups, straight or branched-chain alkyl groups having 1-4 carbon atoms, alkoxy groups having 1-4 carbon atoms, straight or branched-chain alkylmercapto groups having 1-7 carbon atoms, substituted alkylmercapto groups of the general formula II ##STR2## in which n represents 1 or 2, R.sub.3 is a hydrogen atom or a methyl group and R.sub.4 is a hydroxy group or an amino group of the general formula V ##STR3## in which R.sub.8 represents a hydrogen atom or methyl group and R.sub.9 represents a methyl group or substituted or unsubstituted benzyl group, or R.sub.8 and R.sub.

Abstract: .omega.-(2-Oxo-4-imidazolin-1-yl) alkanoic acids and salts and esters thereof of the formula: ##STR1## in which n denotes an integer from 1 to 8, R.sup.1 denotes H, a non-toxic cation or a straight-chain or branched, saturated hydrocarbon group of 1 to 6 carbon atoms, and R.sup.2 denotes an unsubstituted or substituted aromatic radical of formula ##STR2## or naphthyl, the substituents X and Y being identical or different and each representing H, halogen or alkoxy have strong antithrombotic activity and an analgesic effect.

Abstract: The invention provides novel .omega.-(5-alkenylthien-2-yl)alkanecarboxylic acids and their functional derivatives having the formula ##STR1## wherein n is an integer from 1 to 9, inclusive; R.sup.1 is H and R.sup.2 is --OH, or R.sup.1 and R.sup.2 together with the wavy lines represent a keto group; and R.sup.3 is H, C.sub.1 -C.sub.6 straight or branched-chain saturated hydrocarbon, or a pharmaceutically acceptable alkali cation. The 3-oxoalkenyl-substituted compounds of formula (I) are prepared by a Wittig-Horner reaction using a 2-oxoheptylphosphonic acid dialkyl ester and an aldehyde of the formula ##STR2## as starting materials, while the 3-hydroxyalkenyl-substituted compounds are obtained by reduction of the corresponding 3-oxoalkenyl compounds. The esters of formula (I) can also be readily converted to the corresponding acids and salts of formula (I).

Abstract: The invention provides N-propionylsarcosineanilides of the formula: ##STR1## wherein n is an integer of 1 to about 3 and the substituent A which can be the same or different when n is greater than 1 is selected from the group consisting of trifluoromethyl; halogen; nitro; acetyl; a straight-chain or branched alkyl group having 1 to 4 carbon atoms; a straight-chain or branched alkoxy group having 1 to 4 carbon atoms; a straight-chain or branched alkylmercapto group having 1 to 7 carbon atoms; a substituted alkylmercapto group of the formula: ##STR2## wherein n is an integer of 1 or 2, R.sub.1 can represent hydrogen and methyl, and R.sub.2 can represent hydroxyl, and an amino group of the formula:--NR.sub.6 R.sub.7 Vwherein R.sub.6 can represent hydrogen, and methyl, and R.sub.7 can represent methyl, substituted benzyl, and R.sub.6 and R.sub.7, together with the nitrogen, can constitute a substituted pyrrolidine ring; a sulphonyl group of the formula:--SO.sub.2 R.sub.3 IIIwherein R.sub.

Abstract: The present invention is related to the new 2.6-dimethyl-4-(3'-nitrophenyl)-1.4-dihydropyridine-3-carboxylic acid beta-trimethylsilylethyl ester-5-carboxylic acid lower alkyl esters with improved antihypertensive and to a process for the treatment of humans suffering from hypertension with such compounds.

Abstract: (3-Alkylamino-2-hydroxypropoxy)-furan-2-carboxylic acid anilides of the formula: ##STR1## in which R.sub.1 denotes a straight or branched C.sub.1 to C.sub.5 alkyl group or a cyclopropyl or cyclopentyl group, R.sub.2 denotes a hydrogen or halogen atom or a methyl, methoxy, nitro or acetyl group, R.sub.3 denotes a hydrogen or halogen atom or a nitro group and A denotes a single bond or the --CH.sub.2 -- or --CH.dbd.CH-- group, and physiologically tolerated acid addition salts thereof possess .beta.-adrenolytic properties and a low toxicity.

Abstract: Novel n-oleyl derivatives of natural and synthetic phosphatidyl ethanolamines are provided. Such derivatives exhibit antilipemic and antiarteriosclerotic properties and are thus useful in pharmaceutical preparations.

Abstract: An improved process for obtaining highly purified phosphatidylcholines (lecithin) including a high content of essential fatty acids is disclosed. Raw lecithins are first extracted with a lower alcohol of 1 to 3 carbon atoms. The resulting two phases are separated and the alcohol-rich upper phase is treated with an aluminum oxide adsorbent. Elution of the adsorbent with an alcohol (as in known processes) results in an oily phosphatidylcholine, free of cephalin and inositol phosphatides but possessing a high content of essential fatty acids.

Abstract: Processes for preparing benzoylethers, their acid additive salts and their quaternary ammonium salts are disclosed. These compounds have useful pharmacodynamic properties.

Abstract: A compound of the formula ##STR1## (wherein R.sub.1 and R.sub.2 are each H or a fatty-acid residue, and R.sub.3 is ##STR2## and PG is a prostaglandin radical or optical isomer thereof) is found to have a substantially increased duration of effect, compared with the corresponding prostaglandin per se, and also a strong organ specificity.