Patents by Inventor Hans Christian Reinhardt

Hans Christian Reinhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAPKAP kinase-2 as a specific target for blocking proliferation of P53-defective
    Patent number: 9023787
    Abstract: The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: May 5, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Michael B. Yaffe, Isaac A. Manke, Hans Christian Reinhardt
  • Mapkap Kinase-2 as a Specific Target for Blocking Proliferation of P53-Defective Cells
    Publication number: 20140037755
    Abstract: The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.
    Type: Application
    Filed: May 13, 2013
    Publication date: February 6, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Michael B. Yaffe, Isaac A. Manke, Hans Christian Reinhardt
  • Mapkap kinase-2 as a specific target for blocking proliferation of P53-defective cells
    Patent number: 8440610
    Abstract: The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: May 14, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Michael B. Yaffe, Isaac A. Manke, Hans Christian Reinhardt
  • Methods for Diagnosing and Treating Cancer
    Publication number: 20120252737
    Abstract: The invention provides methods for decreasing one or more symptoms of cancer in a patient requiring the steps of determining the activation or inactivation of the MK2 signaling pathway and, based on these determinations, administering either a MK2 inhibitor or a combination of a MK2 inhibitor and a chemotherapeutic agent, or a chemotherapeutic agent to the patient. The invention further provides methods for identifying a cancer patient that may selectively benefit from the administration of a chemotherapeutic agent, or the administration of a MK2 inhibitor or the combination of a MK2 inhibitor and a chemotherapeutic agent, requiring the steps of determining the activation or inactivation of the MK2 signaling pathway. The invention additionally provides methods and kits for diagnosing a chemotherapy-sensitive or chemotherapy-resistant cancer in a subject that require the step of (or reagents for) determining the activation or inactivation of the MK2 signaling pathway.
    Type: Application
    Filed: October 4, 2010
    Publication date: October 4, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Michael B. Yaffee, Hans Christian Reinhardt
  • Methods and compositions for treating cellular proliferative diseases
    Publication number: 20090181468
    Abstract: The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, screening assays for identifying such compounds, and methods for treating such disorders.
    Type: Application
    Filed: July 24, 2008
    Publication date: July 16, 2009
    Inventors: Michael B. Yaffe, Isaac A. Manke, Hans Christian Reinhardt, Daniel Lim
  • Mapkap kinase-2 as a specific target for blocking proliferation of P53-defective cells
    Publication number: 20090010927
    Abstract: The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.
    Type: Application
    Filed: April 24, 2007
    Publication date: January 8, 2009
    Inventors: Michael B. Yaffe, Isaac A. Manke, Hans Christian Reinhardt