Abstract: The present invention relates to a ligand for bacterial toxins, particularly entero- or exotoxins of gram-positive bacteria, which is capable of selective interaction with a structure containing an amino acid sequence conserved in the bacterial toxins. The invention also relates to an adsorbent that exhibits the ligand bound to a matrix, an adsorption device for reducing the concentration of bacterial toxins in blood or blood plasma as well as a pharmaceutical composition, which contains the ligands, and which is suitable in particular for the treatment and/or prevention of gram-positive sepsis.