Patents by Inventor Hans E. Söderlund

Hans E. Söderlund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent kit for determining specific nucleotide variations
    Patent number: 7132235
    Abstract: Detection of variable nucleotide(s) is based on primer extension and incorporation of detectable nucleoside triphosphates. By selecting the detection step primers from the region immediately adjacent to the variable nucleotide, this variation can be detected after incorporation of as few as one nucleoside triphosphate. Labelled nucleoside triphosphates matching the variable nucleotide are added and the incorporation of a label into the detection step primer is measured. The selection of the detection step primer is important to the method according to this invention and is dependent on the nucleotide sequence of interest. The detection step primers are preferably selected so as to span the region immediately toward the 3? end from the variable nucleotide to be detected. The detection step primers can also be complementary to a sequence beginning several nucleotides removed from the variable nucleotide.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 7, 2006
    Assignee: Orchid Cellmark Inc.
    Inventors: Hans E. Söderlund, Anne-Christine Syvanen
  • Method for determining specific nucleotide variations
    Patent number: 7026117
    Abstract: Detection of variable nucleotide(s) is based on primer extension and incorporation of detectable nucleoside triphosphates. By selecting the detection step primers from the region immediately adjacent to the variable nucleotide, this variation can be detected after incorporation of as few as one nucleoside triphosphate. Labelled nucleoside triphosphates matching the variable nucleotide are added and the incorporation of a label into the detection step primer is measured. The selection of the detection step primer is important to the method according to this invention and is dependent on the nucleotide sequence of interest. The detection step primers are preferably selected so as to span the region immediately toward the 3? end from the variable nucleotide to be detected. The detection step primers can also be complementary to a sequence beginning several nucleotides removed from the variable nucleotide.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: April 11, 2006
    Assignee: Orchid BioSciences, Inc.
    Inventors: Hans E. Söderlund, Anne-Christine Syvanen