Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: The present invention concerns a genetically modified bacterium and to its industrial application, in particular in the 1,2-dehydrogenation of steroids.

Abstract: A cooling device for providing cooling capability of adjacent structures comprises a hollow chamber, an inlet and a chamber outlet, wherein the inlet, the chamber and the chamber outlet are configured such that fluid flow may enter via the inlet, pass through the chamber, and exit via the chamber outlet. The chamber is divided into a distribution chamber and a cooling chamber by a partitioning member, wherein the inlet is fluidly connected to the distribution chamber and the chamber outlet is fluidly connected to the cooling chamber. The partitioning member comprises at least a first and a second constriction passage, wherein the first constriction passage has a first predefined cross sectional flow area and the second constriction passage has a second predefined cross sectional flow area.

Abstract: The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.

Abstract: The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.

Abstract: A cooling device for providing cooling capability of adjacent structures comprises a hollow chamber, an inlet and a chamber outlet, wherein the inlet, the chamber and the chamber outlet are configured such that fluid flow may enter via the inlet, pass through the chamber, and exit via the chamber outlet. The chamber is divided into a distribution chamber and a cooling chamber by a partitioning member, wherein the inlet is fluidly connected to the distribution chamber and the chamber outlet is fluidly connected to the cooling chamber. The partitioning member comprises at least a first and a second constriction passage, wherein the first constriction passage has a first predefined cross sectional flow area and the second constriction passage has a second predefined cross sectional flow area.

Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.

Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.

Abstract: The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.

Abstract: An afterburner fuel-feed arrangement including an elongate fuel spraybar for distributing fuel to the afterburner section of a turbo-combustion engine. The spraybar includes a fuel-receiving spray head in fluid communication with a plurality of elongate fuel pipes, which are surrounded by an elongate, aerodynamic-shaped shroud. The surrounded fuel pipes project into an interior through-core of the engine. The shroud has an interior lateral sidewall that includes a pipe-receiving portion configured to abuttingly engage a corresponding shroud-engaging portion of an exterior surface of one of the fuel pipes. The pipe-receiving portion is configured to substantially radially fix a fuel pipe received therein relative to the shroud, thus supporting and bracing the pipe and raising the eigenfrequencies of the assembly into ranges higher than those of the incorporating engine.

Abstract: The invention relates to new fredericamycin derivatives, to pharmaceutical drugs containing them or their salts, and to the use of the fredericamycin derivatives for the treatment of diseases, especially tumor diseases.

Abstract: A fuel injector (1) having a chamber (7) with a fuel inlet (8) and a plurality of fuel outlets (10), and including a fuel distributor (18) that is arranged in the chamber (7) for the purpose of distributing fuel introduced into the chamber (7) via the fuel inlet (8) to the outlets (10). The fuel distributor (18) includes a generally rotary symmetric distributor body (19).

Abstract: Method and apparatus for providing an afterburner fuel-feed arrangement including an elongate fuel spraybar for distributing fuel to the afterburner section of a turbo-combustion engine. The spraybar has a longitudinal axis and includes a fuel-receiving spray head in fluid communication with a plurality of elongate fuel pipes surrounded by an elongate, aerodynamic-shaped shroud. The spray head is configured to be mounted in a casing of a turbo-combustion engine which projects the surrounded fuel pipes into an interior through-core of the engine in cross-wise orientation to a core gas flow thereof. The shroud has an interior lateral sidewall that includes a pipe-receiving portion configured to abuttingly engage a corresponding shroud-engaging portion of an exterior surface of one of the fuel pipes. The pipe-receiving portion is configured to substantially radially fix a fuel pipe, received therein, relative to the shroud.

Abstract: A fuel injector (1) having a chamber (7) with a fuel inlet (8) and a plurality of fuel outlets (10), and including a fuel distributor (18) that is arranged in the chamber (7) for the purpose of distributing fuel introduced into the chamber (7) via the fuel inlet (8) to the outlets (10). The fuel distributor (18) includes a generally rotary symmetric distributor body (19).

Abstract: The invention relates to an apparatus and a method of contact-free, almost continuous measurement and monitoring of the width, thickness and position of magnetic tracks on moving film strips within wide limits of the speed. The track width and track position of the magnetic tracks are measured optically and the magnetically acting track cross section is measured electromagnetically via the track volume. The measured values are together recorded, evaluated and displayed and/or used for recontrolling the casting arrangement for emitting warning signals or for stopping the coating machine.

Abstract: The invention relates to a method of contact-free, almost continuous measurement and monitoring of the width, thickness and position of magnetic tracks on moving film strips within wide limits of the speed. The track width and track position of the magnetic tracks are measured optically and the magnetically acting track cross section is measured electromagnetically via the track volume. The measured values are together recorded, evaluated and displayed and/or used for recontrolling the casting arrangement for emitting warning signals or for stopping the coating machine.