Patents by Inventor Hans Fliri

Hans Fliri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20240352074
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, in particular diseases or conditions associated with cellular injury or cell death, such as organ injury or organ failure, which can be caused by a number of different reasons, such as ischemia or ischemia reperfusion injury, toxins, infection or mechanical trauma.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 24, 2024
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • Cyclophilin inhibitors and uses thereof
    Patent number: 12060440
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, such as organ injury or organ failure.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 13, 2024
    Assignee: FARSIGHT MEDICAL TECHNOLOGY (SHANGHAI) CO., LTD.
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20230203099
    Abstract: Provided are compounds as defined by Formula 1 and uses thereof for the prevention or treatment of disease or conditions such as organ injury or organ failure.
    Type: Application
    Filed: March 25, 2021
    Publication date: June 29, 2023
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • PREVENTION AND TREATMENT OF ORGAN INJURIES
    Publication number: 20230181680
    Abstract: The invention provides for Compound I or a pharmaceutically acceptable salt thereof (I) for use in the prevention and/or treatment of an organ injury, or a condition associated with an organ injury, in a subject diagnosed with, or suffering from an infection.
    Type: Application
    Filed: April 15, 2021
    Publication date: June 15, 2023
    Inventors: Ching-Pong Mak, Fashu Ma, Dong Xiao, Michael Peel, Hans Fliri
  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20230110497
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, such as organ injury or organ failure.
    Type: Application
    Filed: September 16, 2022
    Publication date: April 13, 2023
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • Cannabinoid-2 agonists
    Patent number: 9670216
    Abstract: The present specification discloses cannabinoid-2 agonists, compositions comprising such cannabinoid-2 agonists, and methods of treating an individual suffering from a disease by administering compositions comprising such cannabinoid-2 agonists.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: June 6, 2017
    Assignee: ALLERGAN, INC.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • CANNABINOID-2 AGONISTS
    Publication number: 20150284400
    Abstract: The present specification discloses cannabinoid-2 agonists, compositions comprising such cannabinoid-2 agonists, and methods of treating an individual suffering from a disease by administering compositions comprising such cannabinoid-2 agonists.
    Type: Application
    Filed: June 22, 2015
    Publication date: October 8, 2015
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Cannabinoid-2 agonists
    Patent number: 9062004
    Abstract: The present specification discloses cannabinoid-2 agonists, compositions comprising such cannabinoid-2 agonists, and methods of treating an individual suffering from a disease by administering compositions comprising such cannabinoid-2 agonists.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: June 23, 2015
    Assignee: Allergan, Inc.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal cannabidiols as agents for lowering intraocular pressure
    Patent number: 8420637
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: April 16, 2013
    Assignee: Allergan, Inc.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal cannabidiols as agents for lowering intraocular pressure
    Patent number: 7718830
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: May 18, 2010
    Assignee: Allergan, Inc.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE
    Publication number: 20100010027
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal Cannabidiols as agents for lowering intraocular pressure
    Patent number: 7618966
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: November 17, 2009
    Assignee: Allergan, Inc.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal cannabidiols as agents for lowering intraocular pressure
    Patent number: 7612101
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: November 3, 2009
    Assignee: Allergan, Inc.
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • NOVEL PROSTAMIDE RECEPTOR ANTAGONISTS
    Publication number: 20080096240
    Abstract: The present invention provides prostamide receptor antagonist compounds that may be represented by the general formula I. wherein A, R1, R2, R3, R4 and R6 are as defined in the specification.
    Type: Application
    Filed: October 9, 2007
    Publication date: April 24, 2008
    Inventors: David Woodward, Jenny Wang, Clive Cornell, Hans Fliri, Jose Martos, Simon Pettit
  • Abnormal Cannabidiols as agents for lowering intraocular pressure
    Publication number: 20070249602
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Application
    Filed: April 24, 2006
    Publication date: October 25, 2007
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal cannabidiols as agents for lowering intraocular pressure
    Publication number: 20070249731
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Application
    Filed: April 24, 2006
    Publication date: October 25, 2007
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • Abnormal Cannabidiols as agents for lowering intraocular pressure
    Publication number: 20070249581
    Abstract: The present invention provides a method of treating glaucoma or ocular hypertension which comprises applying to the eye of a person in need thereof an amount sufficient to treat glaucoma or ocular hypertension of a compound of formula I wherein Y, Q, Z, R, R1 and R2 are as defined in the specification. The present invention further comprises pharmaceutical compositions, e.g. ophthalmic compositions, including said compound of formula I.
    Type: Application
    Filed: April 24, 2006
    Publication date: October 25, 2007
    Inventors: June Chen, Simon Pettit, Hans Fliri
  • 3-Ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
    Publication number: 20060160727
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Application
    Filed: March 21, 2006
    Publication date: July 20, 2006
    Inventors: Hans Fliri, David Houck
  • 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
    Publication number: 20060089301
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Application
    Filed: September 30, 2005
    Publication date: April 27, 2006
    Inventors: Hans Fliri, David Houck
  • Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases
    Publication number: 20060089400
    Abstract: The invention provides new spiro and carboxylic acid derivatives, pharmaceutically compositions comprising them and their use for the preparation of pharmaceutical compositions.
    Type: Application
    Filed: May 2, 2003
    Publication date: April 27, 2006
    Applicant: The Vernalis Group of Companies
    Inventors: Birte Hernandez Alvarez, Gunter Fischer, Manfred Braun, Anahita Hessamian-Alinejad, Hans Fliri