Patents by Inventor Hans-Friedrich GRUNERT

Hans-Friedrich GRUNERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody anti-FGFR4
    Patent number: 11643467
    Abstract: The present disclosure relates to monoclonal antibodies anti-FGFR4 and their use as medicaments and diagnostic agents. In particular, it relates to an antibody which specifically binds to the acid box domain of FGFR4 and to specific portions thereof. Nucleic acids coding for said antibody, vectors and host cells for their expression and production, antibody-drug conjugates and pharmaceutical compositions comprising said antibody are also within the scope of the present disclosure. The present disclosure also relates to antibodies anti-FGFR4 for use for detecting, killing, affecting or inhibiting development and/or differentiation of colon cancer stem cells.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: May 9, 2023
    Assignee: EXIRIS S.R.L.
    Inventors: Paola Gallinari, Chantal Paolini, Gessica Filocamo, Mirko Brunetti, Armin Lahm, Hans-Friedrich Grunert, John Thompson, Lucia Ricci-Vitiani, Mauro Biffoni
  • MONOCLONAL ANTIBODY ANTI-FGFR4
    Publication number: 20210230280
    Abstract: The present disclosure relates to monoclonal antibodies anti-FGFR4 and their use as medicaments and diagnostic agents. In particular, it relates to an antibody which specifically binds to the acid box domain of FGFR4 and to specific portions thereof. Nucleic acids coding for said antibody, vectors and host cells for their expression and production, antibody-drug conjugates and pharmaceutical compositions comprising said antibody are also within the scope of the present disclosure. The present disclosure also relates to antibodies anti-FGFR4 for use for detecting, killing, affecting or inhibiting development and/or differentiation of colon cancer stem cells.
    Type: Application
    Filed: August 1, 2018
    Publication date: July 29, 2021
    Inventors: Paola GALLINARI, Chantal PAOLINI, Gessica FILOCAMO, Mirko BRUNETTI, Armin LAHM, Hans-Friedrich GRUNERT, John THOMPSON, Lucia RICCI-VITIANI, Mauro BIFFONI