Patents by Inventor Hans-G. Klingemann

Hans-G. Klingemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10517895
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: December 31, 2019
    Assignee: NANTKWEST, INC.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20190365816
    Abstract: This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.
    Type: Application
    Filed: August 15, 2019
    Publication date: December 5, 2019
    Inventors: Tien Lee, Hans G. Klingemann, Barry J. Simon, Laurent Boissel
  • Patent number: 10456420
    Abstract: This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: October 29, 2019
    Assignee: NantKwest, Inc.
    Inventors: Tien Lee, Hans G. Klingemann, Barry J. Simon, Laurent Boissel
  • Publication number: 20190192570
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Applicant: NantKwest, Inc.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20190192569
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Applicant: NantKwest, Inc.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20190192568
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Applicant: NantKwest, Inc.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20190125801
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Application
    Filed: December 6, 2018
    Publication date: May 2, 2019
    Applicant: NantKwest, Inc.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Patent number: 10258649
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: April 16, 2019
    Assignee: NANTKWEST, INC.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20180193383
    Abstract: This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.
    Type: Application
    Filed: March 25, 2016
    Publication date: July 12, 2018
    Applicant: NantKwest, Inc.
    Inventors: Tien Lee, Hans G. Klingemann, Barry J. Simon, Laurent Boissel
  • Publication number: 20170304364
    Abstract: This disclosure is directed to compositions and methods for treating cancer using combination therapies of NK-92 cells with cancer drugs (e.g. thalidomide, cisplatin, and paclitaxel).
    Type: Application
    Filed: March 25, 2016
    Publication date: October 26, 2017
    Applicant: NantKwest, Inc.
    Inventors: Tien Lee, Hans G. Klingemann, Barry J. Simon
  • Publication number: 20170182292
    Abstract: Disclosed herein are methods for treating solid mass tumors with direct delivery of an anti-tumor immunotherapeutic agent to the tumor site. In one aspect, this invention encompasses methods of treating solid mass tumors by direct microinjection via a microcatheter of an anti-tumor immunotherapeutic agent into the microvasculature leading into tumor thereby providing high levels of contact with the tumor while minimizing the degree of systemic buildup of the immunotherapeutic agent.
    Type: Application
    Filed: May 21, 2015
    Publication date: June 29, 2017
    Applicant: NANTKWEST, INC.
    Inventor: Hans G. Klingemann
  • Publication number: 20160250256
    Abstract: Provided herein are pharmaceutical compositions comprising tumoricidal and/or antimicrobial components isolated from the supernatant of NK-92 cell medium and methods of using the compositions for killing cancer cells.
    Type: Application
    Filed: October 28, 2014
    Publication date: September 1, 2016
    Applicant: NantKwest, Inc.
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Publication number: 20160244716
    Abstract: Described herein is a storage medium for transport of NK-92 cells comprising human serum, about 200 IU/mL and a density of non-irradiated NK-92 cells sufficient to provide a therapeutic amount of NK-92 cells at the time of delivery to a treatment facility, wherein the temperature of the medium is maintained within +/?5° C. of a selected temperature between 20° C. and 40° C., such that the NK-92 cells remain viable for administration to a patient for up to a period of at least 24 hours after placement into the storage medium. Also described are methods of transporting NK-92 cells such that the NK-92 cells remain viable for administration to a patient for up to a period of at least 24 hours after placement into the storage medium.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 25, 2016
    Inventors: Hans G. Klingemann, Barry J. Simon
  • Patent number: 8124069
    Abstract: The invention provides relatively short immunogenic peptides, and biologically active variants thereof, associated with leukemia which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: February 28, 2012
    Assignee: Rush University Medical Center
    Inventors: Joo-Eun Bae, Hans-G. Klingemann
  • Publication number: 20090227020
    Abstract: The invention provides relatively short immunogenic peptides, and biologically active variants thereof, associated with leukemia which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.
    Type: Application
    Filed: March 20, 2009
    Publication date: September 10, 2009
    Inventors: Joo-eun BAE, Hans-G. KLINGEMANN
  • Patent number: 7527793
    Abstract: The invention provides relatively short immunogenic peptides, and biologically active variants thereof, associated with leukemia which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: May 5, 2009
    Assignee: Rush University Medical Center
    Inventors: Joo-eun Bae, Hans-G. Klingemann
  • Publication number: 20040009186
    Abstract: The invention provides relatively short immunogenic peptides, and biologically active variants thereof, associated with leukemia which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.
    Type: Application
    Filed: May 2, 2003
    Publication date: January 15, 2004
    Applicant: Rush-Presbyterian-St. Luke's Medical Center
    Inventors: Joo-Eun Bae, Hans-G. Klingemann
  • Publication number: 20030206916
    Abstract: The invention provides relatively short immunogenic peptides, and biologically active variants thereof, associated with leukemia which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.
    Type: Application
    Filed: May 3, 2002
    Publication date: November 6, 2003
    Applicant: Rush-Presbyterian-St. Luke's Medical Center
    Inventors: Joo-Eun Bae, Hans-G. Klingemann