Abstract: The disclosure concerns an isolation apparatus useful for medical, biological, chemical, physical, or the like experiments and treatments. A flexible envelope in the form of an elongated sack is divided lengthwise into a plurality of sealed sections. The envelope is a transparent material and also includes a viewing window into the interior. At least one glove is formed in the envelope. Exit and entrance tubes for liquids and gases enable pressurizing of the sections and inlet and outlet of fluids from the sections. There is a sealable lock at one end of the envelope. Sealable openings along the length of the envelope allow an object within the envelope to have portions thereof, e.g. arms of a body, project out of the envelope.