Patents by Inventor Hans G. W. Leuenberger

Hans G. W. Leuenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process to produce alpha-substituted derivatives of 3-hydroxypropionic acid
    Patent number: 4734367
    Abstract: The manufacture of optically active compounds of the formula ##STR1## wherein R.sup.1 signifies alkyl, phenyl or benzyl and R.sup.2 signifies hydrogen or a customary ester residue,by the fermentative reduction of compounds of the formula ##STR2## wherein R.sup.1 and R.sup.2 have the above significance. The compounds obtained are valuable intermediates in organic syntheses.
    Type: Grant
    Filed: November 23, 1984
    Date of Patent: March 29, 1988
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans G. W. Leuenberger, Peter K. Matzinger, Dieter Seebach, Max F. Zuger
  • Process for the manufacture of tertiary, optically active aliphatic compounds
    Patent number: 4305876
    Abstract: A process for asymmetrically hydrogenating through the use of microorganisms a double bond connected to tertiary carbon atom in an olefinic aliphatic compound to produce a tertiary, optically active aliphatic compound useful as an intermediate for optically active Vitamins E and K.
    Type: Grant
    Filed: November 24, 1978
    Date of Patent: December 15, 1981
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Richard Barner, Walter Boguth, Hans G. W. Leuenberger, Max Schmid, Reinhard Zell
  • Process for the manufacture of cyclohexene derivatives
    Patent number: 4283559
    Abstract: The compound 6-hydroxy-3-(5-hydroxy-3-methyl-1,3-pentadienyl)-2,4,4-trimethyl-2-cyclohe xen-1-one useful as intermediate for producing the natural coloring agent astaxanthin as well as a method for synthesizing astaxanthin from this compound and synthesizing the compound from 2-hydroxyketo isophorone.
    Type: Grant
    Filed: May 21, 1979
    Date of Patent: August 11, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Emil A. Broger, Yvo Crameri, Hans G. W. Leuenberger, Erich Widmer, Reinhard Zell
  • Optically active cyclohexane derivatives
    Patent number: 4156100
    Abstract: A process for fermentatively hydrogenating and reducing ketoisophorone to produce optically active [4R,6R]-4-hydroxy-2,6,6-trimethyl-cyclohexanone useful as an intermediate in the production of optically active carotenoids and intermediates in the production of these carotenoids.
    Type: Grant
    Filed: November 7, 1977
    Date of Patent: May 22, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Walter Boguth, Hans G. W. Leuenberger, Hans J. Mayer, Erich Widmer, Reinhard Zell
  • Process for the manufacture of tertiary, optically active aliphatic compounds
    Patent number: 4138289
    Abstract: A process for asymmetrically hydrogenating through the use of microorganisms a double bond connected to tertiary carbon atom in an olefinic aliphatic compound to produce a tertiary, optically active aliphatic compound useful as an intermediate for optically active Vitamins E and K.
    Type: Grant
    Filed: May 2, 1977
    Date of Patent: February 6, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Richard Barner, Walter Boguth, Hans G. W. Leuenberger, Max Schmid, Reinhard Zell
  • Optically active cyclohexane derivatives
    Patent number: 4072715
    Abstract: A process for fermentatively hydrogenating and reducing ketoisophorone to produce optically active [4R,6R]-4-hydroxy-2,6,6-trimethyl-cyclohexanone useful as an intermediate in the production of optically active carotenoids and intermediates in the production of these carotenoids.
    Type: Grant
    Filed: July 20, 1976
    Date of Patent: February 7, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Walter Boguth, Hans G. W. Leuenberger, Hans J. Mayer, Erich Widmer, Reinhard Zell