Abstract: A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.

Abstract: A filter for filtering debris out of a fluid flowing along a fluid flow direction in a fluidic member of a sample separation device, the filter comprising a plurality of filter structures stacked along the fluid flow direction and each having pores with defined pore size, wherein the defined pore size of the stacked filter structures decreases along the fluid flow direction.

Abstract: A fluid supply system (150) adapted for metering two or more fluids in controlled proportions and for supplying a resultant mixture, the fluid supply system (150) comprising a plurality of solvent supply lines (104 to 107), each fluidically connected with a fluid source (100 to 103) providing a respective fluid, a pumping unit (110) comprising a reciprocating element (115) adapted for intaking fluid supplied at an inlet of the pumping unit (110) and for supplying the pressurized fluid at an outlet of the pumping unit (110), wherein the pumping unit (110) is adapted for taking in fluids from selected solvent supply lines (104 to 107) and for supplying a pressurized mixture of the fluids at its outlet, a proportioning valve (108) interposed between the solvent supply lines (104 to 107) and the inlet of the pumping unit (110), the proportioning valve (108) adapted for modulating solvent composition by sequentially coupling selected ones of the solvent supply lines (104 to 107) with the inlet of the pumping unit

Abstract: A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.

Abstract: A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.

Abstract: A filter for filtering debris out of a fluid flowing along a fluid flow direction in a fluidic member of a sample separation device, the filter comprising a plurality of filter structures stacked along the fluid flow direction and each having pores with defined pore size, wherein the defined pore size of the stacked filter structures decreases along the fluid flow direction.

Abstract: A fluid supply system (150) adapted for metering two or more fluids in controlled proportions and for supplying a resultant mixture, the fluid supply system (150) comprising a plurality of solvent supply lines (104 to 107), each fluidically connected with a fluid source (100 to 103) providing a respective fluid, a pumping unit (110) comprising a reciprocating element (115) adapted for intaking fluid supplied at an inlet of the pumping unit (110) and for supplying the pressurized fluid at an outlet of the pumping unit (110), wherein the pumping unit (110) is adapted for taking in fluids from selected solvent supply lines (104 to 107) and for supplying a pressurized mixture of the fluids at its outlet, a proportioning valve (108) interposed between the solvent supply lines (104 to 107) and the inlet of the pumping unit (110), the proportioning valve (108) adapted for modulating solvent composition by sequentially coupling selected ones of the solvent supply lines (104 to 107) with the inlet of the pumping unit

Abstract: A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.

Abstract: A pump control for controlling a fluid pump for pumping a fluid, the pump control comprising a pump oil path comprising an oil pump and at least one valve, the oil pump being adapted for pumping pump oil to the fluid pump, the at least one valve being arranged downstream of the oil pump, and a control unit adapted for controlling a pump oil pressure in the fluid pump by switching the at least one valve so that the fluid can be pumped in response to the pump oil pressure.

Abstract: A pumping apparatus for a high performance liquid chromatography system (350) is disclosed. The pumping apparatus comprises a piston (1) for reciprocation in a pump working chamber (3) to compress liquid in the pump working chamber (3) to a high pressure at which compressibility of the liquid becomes noticeable. At least one of the piston (1) and the pump working chamber (3) is at least partially coated with or comprised of silicon carbide.

Abstract: A pumping apparatus (10), for delivering liquid at a high pressure at which compressibility of the liquid becomes noticeable, comprises a piston (20) adapted for reciprocation in a pump working chamber (30), wherein a movement of the piston (20) into a first direction (40) decreases a first volume (V1) in the pump working chamber (30) and increases a second volume (V2) in the pump working chamber (30), and a movement of the piston (20) into a second direction (50) opposite to the first direction (40) increases the first volume (V1) and decreases the second volume (V2). A coupling (70, 80, 90, 100) is provided for coupling the first volume (V1) with the second volume (V2) as long as a pressure (Psup) in the first volume (V1) exceeds a pressure in the second volume (V2). An outlet valve (120) is provided for coupling the second volume (V2) with an outlet (110) of the pumping apparatus (10) as long as a pressure in the second volume (V2) exceeds a pressure (Psys) at the outlet (110).

Abstract: A pumping apparatus is provided, which comprises a piston (1) for reciprocation in a pump working chamber (3), a valve, coupled to said pump working chamber (3) in order to permit liquid flow only unidirectional and a drive unit for reciprocating said piston (1). The liquid in said pump working chamber (3) is compressed to a high pressure, at which compressibility of the liquid becomes noticeable. The piston (1) is at least partially coated with a diamond-like carbon coating (2), adapted to provide a reduced abrasion of said piston (1).

Abstract: An intermediate piece for connection between a column tube, adapted for containing a fluid separation material for separating different compounds of a fluid, and a fitting element adapted for fitting the column tube to another element within a fluid path, the intermediate piece comprising a tapered section adapted for spatially distributing the fluid between the fitting element and the column tube, a flow-through element having an open channel through which the fluid is transportable, and a sleeve element adapted to be put as a cap onto an end portion of the column tube and having a through hole. The flow-through element is insertable or inserted in the through hole, and the hardness of the flow-through element is higher than the hardness of the sleeve element.

Abstract: A conduit for drawing off and/or supplying a fluid, for use in microfluidic analytical equipment, includes an elongated first tube having a first channel that is open to the outside in the area of a free end of the conduit and a second tube having a second channel arranged along the first channel that is also open to the outside in the area of the free end of the conduit, where the second channel is spiral-wound.

Abstract: The volumetric flow rate of a fluid is determined essentially independently of the properties of the fluid by guiding the volumetric fluid flow to be measured through an essentially linear flow resistor. An alternating flow of the fluid is superimposed on the volumetric fluid flow to be measured. Steady and alternating components of a pressure drop across the flow resistor are detected. A quantity representative of a property of the fluid is determined in response to the determined alternating component. The volumetric flow rate is calculated on the basis of the determined steady component and the quantity representing fluid property.

Abstract: A pumping system for pumping fluids at sub-ambient temperatures where the pumping fluid, after it has been used for its analytical application, is expanded such that the energy of expansion of the pumping fluid can be employed for cooling the pump head or pumping fluid prior to pumping.

Abstract: A new mechanism for pulsation damping in a reciprocating diaphragm pump system is disclosed which is especially suitable for solvent delivery in modern high pressure liquid chromatography requiring a wide range of solvent flow rates and pressures. The disclosed damper has good overall performance over the full range of liquid chromatographic conditions, a dead volume independent of solvent pressure, and largely eliminates the necessity for continuously pumping the working oil of the diaphragm pump to a maximum operating pressure.