Patents by Inventor Hans Georg Ihlenfeldt

Hans Georg Ihlenfeldt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7625735
    Abstract: A recombinant Drosophila melanogaster deoxynucleoside kinase that remains stable during the synthesis of nucleoside monophosphate without the addition of stabilizing SH reagents or stabilizing proteins, and that accepts all four natural deoxynucleotides is provided. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: December 1, 2009
    Assignee: Roche Diagnostic Operations, Inc.
    Inventors: Hans-Georg Ihlenfeldt, Brigitte Munch-Petersen, Jure Piskur, Leif Sondergaard
  • Publication number: 20080280329
    Abstract: The present invention relates to a method for the in vitro synthesis of deoxyribonucleosides and enzymes suitable for this method.
    Type: Application
    Filed: May 3, 2007
    Publication date: November 13, 2008
    Inventors: Wilhelm Tischer, Hans-Georg Ihlenfeldt, Octavian Barzu, Hiroshi Sakamoto, Elisabeth Pistotnik, Philippe Marliere, Sylvie Pochet
  • Patent number: 7229797
    Abstract: The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: June 12, 2007
    Assignee: Institut Pasteur
    Inventors: Wilhelm Tischer, Hans-Georg Ihlenfeldt, Octavian Barzu, Hiroshi Sakamoto, Elisabeth Pistotnik, Philippe Marlière, Sylvie Pochet
  • Publication number: 20060252131
    Abstract: Recombinant kinase remaining stable during the synthesis of necleoside monophosphate without the addition of stabilizing SH reagents, without stabilizing proteins and accepting all four natural deoxynucleotides, obtainable from insect cells such as e.g. Drosophila Melanogaster. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.
    Type: Application
    Filed: October 7, 2003
    Publication date: November 9, 2006
    Inventors: Hans-Georg Ihlenfeldt, Brigitte Munch-Petersen, Jure Piskur, Leif Sondergaard
  • Patent number: 6916616
    Abstract: The invention concerns stable aqueous solutions containing one or several nucleoside triphosphates wherein the respective solution has a pH value of more than 7.5 and contains no additional substances with a stabilizing effect. The nucleoside triphosphate solutions are used in particular for DNA synthesizing reactions such as e.g. RT-PCR, cycle sequencing, random priming and nick translation. One of the most important applications of such solutions containing deoxy-nucleoside triphosphates (d-NTP) is their use in the polymerase chain reaction (PCR).
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: July 12, 2005
    Assignee: Roche Diagnostics GmbH
    Inventors: Hans-Georg Ihlenfeldt, Axel Schmidt, Klaus Muhlegger, Volker Leitenberger
  • Publication number: 20030198644
    Abstract: Novel HCV peptide antigens are described representing partial sequences of the C-100-3 and env/core with C-regions. These peptide antigens are suitable for the determination of HCV antibodies as immunogens for the production of antibodies against HCV and as vaccines for the production of vaccines against HCV.
    Type: Application
    Filed: February 21, 2003
    Publication date: October 23, 2003
    Applicant: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Gertraud Ehrlich-Weinreich, Hubert Bayer, Ursula Henrike Wienhues, Gunther Gerhard Jung, Hans Georg Ihlenfeldt
  • Patent number: 6592871
    Abstract: Novel HCV peptide antigens are described representing partial sequences of the C-100-3 and env/core with C-regions. These peptide antigens are suitable for the determination of HCV antibodies as immunogens for the production of antibodies against HCV and as vaccines for the production of vaccines against HCV.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: July 15, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Gertraud Ehrlich-Weinreich, Hubert Bayer, Ursula Henrike Wienhues, Günther Gerhard Jung, Hans Georg Ihlenfeldt
  • Publication number: 20030108974
    Abstract: The invention concerns a method for typing antibodies in a sample liquid by means of type-specific antigens and in particular a method for typing antibodies to the hepatitis C virus and peptide antigens suitable for this.
    Type: Application
    Filed: July 17, 2002
    Publication date: June 12, 2003
    Applicant: Roche Diagnostics GmbH
    Inventors: Cristoph Seidel, Ursula-Henrike Wienhues-Thelen, Urban Schmitt, Gunther-Gerhard Jung, Hans-Georg Ihlenfeldt, Wolfgang Kraas
  • Publication number: 20020192788
    Abstract: Recombinant kinase remaining stable during the synthesis of nucleoside monophosphate without the addition of stabilizing SH reagents, without stabilizing proteins and accepting all four natural deoxynucleotides, obtainable from insect cells such as e.g. Drosophila Melanogaster. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.
    Type: Application
    Filed: October 12, 1999
    Publication date: December 19, 2002
    Inventors: HANS-GEORG IHLENFELDT, BRIGITTE MUNCH-PETERSEN, JURE PISKUR, LEIF SONDERGAARD
  • Patent number: 6447992
    Abstract: The invention concerns a method for typing antibodies in a sample liquid by means of type-specific antigens and in particular a method for typing antibodies to the hepatitis C virus and peptide antigens suitable for this.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: September 10, 2002
    Assignee: Roche Diagnostics Gmbh
    Inventors: Cristoph Seidel, Ursula-Henrike Wienhues-Thelen, Urban Schmitt, Günther-Gerhard Jung, Hans-Georg Ihlenfeldt, Wolfgang Kraas
  • Publication number: 20020119534
    Abstract: The invention concerns stable aqueous solutions containing one or several nucleoside triphosphates wherein the respective solution has a pH value of more than 7.5 and contains no additional substances with a stabilizing effect. The nucleoside triphosphate solutions are used in particular for DNA synthesizing reactions such as e.g. RT-PCR, cycle sequencing, random priming and nick translation. One of the most important applications of such solutions containing deoxy-nucleoside triphosphates (d-NTP) is their use in the polymerase chain reaction (PCR).
    Type: Application
    Filed: December 19, 2001
    Publication date: August 29, 2002
    Inventors: Hans-Georg Ihlenfeldt, Axel Schmidt, Klaus Muhlegger, Volker Leitenberger
  • Publication number: 20020004230
    Abstract: The invention concerns stable aqueous solutions containing one or several nucleoside triphosphates wherein the respective solution has a pH value of more than 7.5 and contains no additional substances with a stabilizing effect. The nucleoside triphosphate solutions are used in particular for DNA synthesizing reactions such as e.g. RT-PCR, cycle sequencing, random priming and nick translation. One of the most important applications of such solutions containing deoxynucleoside triphosphates (d-NTP) is their use in the polymerase chain reaction (PCR).
    Type: Application
    Filed: November 19, 1999
    Publication date: January 10, 2002
    Inventors: HANS-GEORG IHLENFELDT, AXEL SCHMIDT, KLAUS MUHLEGGER, VOLKER LEITENBERGER
  • Patent number: 6183949
    Abstract: Novel HCV peptide antigens are described representing partial sequences of the C-100-3 and env/core with C-regions. These peptide antigens are suitable for the determination of HCV antibodies as immunogens for the production of antibodies against HCV and as vaccines for the production of vaccines against HCV.
    Type: Grant
    Filed: February 21, 1996
    Date of Patent: February 6, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Christoph Seidel, Gertraud Ehrlich-Weinreich, Hubert Bayer, Ursula H Wienhues, Günther Gerhard Jung, Hans Georg Ihlenfeldt
  • Patent number: 5935778
    Abstract: The invention concerns a method for typing antibodies in a sample liquid by means of type-specific antigens and in particular a method for typing antibodies to the hepatitis C virus and peptide antigens suitable for this.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: August 10, 1999
    Assignee: Boehringer Mannheim GmbH
    Inventors: Cristoph Seidel, Ursula-Henrike Wienhues-Thelen, Urban Schmitt, Gunther-Gerhard Jung, Hans-Georg Ihlenfeldt, Wolfgang Kraas
  • Patent number: 5674676
    Abstract: New HCV peptide antigens are described. These peptide antigens are suitable for the determination of HCV antibodies as immunogens for the preparation of antibodies to HCV and as immunogens for the preparation of vaccines to HCV.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: October 7, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Christoph Seidel, Ursula-Henrike Wienhues, Hubert Bayer, Guenther-Gerhard Jung, Hans Georg Ihlenfeldt