Abstract: A hand drive assembly for a wheelchair is disclosed. The assembly comprises a main axle adapted to be installed on each side of a regular wheelchair for rotatably mounting the wheel of the chair, a main gear rotatably mounted on the main axle and adapted to be coupled to the wheel, an elongated plate mounted upwardly at one end on the main axle and at a predetermined angular position with respect to the vertical ahead of the wheel, a driving axle rotatably mounted at the other end of the gear plate, a driving gear secured to the driving axle, a hand drive ring coupled to the driving axle for driving such driving gear, and an intermediate gear rotatably mounted on the gear plate and coupling the driving gear to the main gear to transmit motion of the hand drive ring to the regular wheel of the wheelchair.