Abstract: A strapping apparatus (10) for packages, has a packing table (11) on which the package (13) to be strapped lies. The apparatus has vertically oriented supports (17) which are arranged laterally on the packing table (11), a horizontally oriented pressing plate (18) which is arranged on the vertical supports (11) and which is movable in a vertical direction, and a device, situated on the pressing plate (18), for the arrangement of an edge protection means on the package (13) lying on the packing table (11). The device for the arrangement of the edge protection means can be moved from an initial position remote from the package into an arrangement position close to the package (13). The device includes at least one magazine (19), arranged on the pressing plate (18), for the supply of edge protection means and has a first clearance outline profile which is delimited by the packing table (11), the vertical supports (17), the pressing plate (18) and the at least one magazine (19).

Abstract: A device arranges an edge protector on a package. The device includes a drive wheel for moving the device along a guiding rail from a point of departure to the package and from the package to the point of departure. A motor is carried by the device and drives the drive wheel. A clamp mount includes a movable clamping jaw and a counter bearing for taking up the edge protector in an open position of the clamping jaw and to hold it in a closed position of the clamping jaw. The motor drives the drive wheel and acts on a power transmission assembly to induce opening and closing of the clamping jaw. A device for strapping packages having the edge protector applicator includes a frame carrying a press plate above a vertically movable packing table. The press plate has running rails on which the edge protector applicator is movably mounted. The applicator device is mounted below the press plate.

Abstract: A measuring device in which a non-electrical variable is converted into an electrical measurement signal via an electrical alternating current having a frequency, wherein the measurement signal contains a signal portion dependent on the non-electrical variable and is double the frequency, and a fault signal portion dependent on the alternating current and is at the frequency, where the measurement signal is pre-processed and digitized to generate a digital signal that is detected and processed to generate a measured value proportional to the non-electrical variable and to generate a fault signal value, wherein the fault signal value is utilized to normalize the measured value that is normalized in a normalizing stage, by forming the quotient using the square of the fault signal value, and is output as a normalized measured value.

Abstract: The present invention relates to chemical compounds that can in particular be used as structural mimetics of proline-rich peptides. The compounds of the present invention are capable of selectively inhibiting ena/VASP-EVH1-mediated protein-protein interactions. The invention further relates to the use of said compounds as pharmaceutical agents and to the use of the pharmaceutical agents to treat tumor diseases. The chemical compounds of the present invention can significantly inhibit the chemotaxis and motility of invasive tumor cells and can therefore be used in the treatment and/or prevention of tumor metastases.

Abstract: A method of manufacturing a transfer assembly for transferring articles from a first moving carrier to a second moving carrier is provided. The method comprises providing a programmable motor and a motor control system. The motor control system and the programmable motor define an excitation frequency. The method comprises providing a carrier member comprising a housing comprising a wall and shifting a natural frequency of the carrier member by forming the wall with a first carbon fiber layer having a first fiber orientation extending in a first direction and with a second carbon fiber layer having a second fiber orientation extending in a second direction that is different than the first direction. The shifting the natural frequency establishes the natural frequency of the carrier member to be at least 1.1 times greater than or at least 1.1 times less than the excitation frequency.

Abstract: The invention relates to the use of polyolefins modified with one or more silanes as adhesion promoters for the production of flat glass/glass, glass/plastic, or plastic/plastic laminates, to corresponding laminates, and to displays containing the laminates according to the invention.

Abstract: An apparatus for transferring one or more articles from a first carrier moving at a first speed to a second carrier moving at a second speed that is different than the first speed is provided. The apparatus comprises a programmable motor and a carrier member operably engaged with the programmable motor. The carrier member comprises a housing comprising a wall and an outer surface configured to receive the one or more articles from the first moving carrier in a receiving zone and configured to deposit the one or more articles onto the second moving carrier in an application zone. The wall comprises carbon fiber. The programmable motor is configured to move the outer surface of the housing at a third speed through the receiving zone and at a fourth speed through the application zone.

Abstract: A method of manufacturing a transfer assembly for transferring articles from a first moving carrier to a second moving carrier is provided. The method comprises providing a programmable motor and a motor control system. The motor control system and the programmable motor define an excitation frequency. The method comprises providing a carrier member comprising a housing comprising a wall and shifting a natural frequency of the carrier member by forming the wall with a first carbon fiber layer having a first fiber orientation extending in a first direction and with a second carbon fiber layer having a second fiber orientation extending in a second direction that is different than the first direction. The shifting the natural frequency establishes the natural frequency of the carrier member to be at least 1.1 times greater than or at least 1.1 times less than the excitation frequency.

Abstract: An apparatus for transferring one or more articles from a first carrier moving at a first speed to a second carrier moving at a second speed that is different than the first speed is provided. The apparatus comprises a programmable motor and a carrier member operably engaged with the programmable motor. The carrier member comprises a housing comprising a wall and an outer surface configured to receive the one or more articles from the first moving carrier in a receiving zone and configured to deposit the one or more articles onto the second moving carrier in an application zone. The wall comprises carbon fiber. The programmable motor is configured to move the outer surface of the housing at a third speed through the receiving zone and at a fourth speed through the application zone.

Abstract: The invention relates to suppressors of endogenous human interferon-gamma (INF-?) applicable in treatment of diseases associated with impaired activity of endogenous IFN-?. The suppressors of the invention are useful in treating autoimmune diseases and for prevention of graft arteriosclerosis and rejection of organs in allograft transplanted patients. The invention includes inactive analogues or variants of IFN-? having preserved affinity to the IFN-? receptor, genetically modified in the domain responsible for triggering the signal transduction pathway.

Abstract: A device arranges an edge protector on a package. The device includes a drive wheel for moving the device along a guiding rail from a point of departure to the package and from the package to the point of departure. A motor is carried by the device and drives the drive wheel. A clamp mount includes a movable clamping jaw and a counter bearing for taking up the edge protector in an open position of the clamping jaw and to hold it in a closed position of the clamping jaw. The motor drives the drive wheel and acts on a power transmission assembly to induce opening and closing of the clamping jaw. A device for strapping packages having the edge protector applicator includes a frame carrying a press plate above a vertically movable packing table. The press plate has running rails on which the edge protector applicator is movably mounted. The applicator device is mounted below the press plate.

Abstract: The invention relates to compounds that can be used, in particular, as structural mimetics of proline-rich peptides and are correspondingly able to bond with proline-rich-motif binding domains (PRM domains) of proteins. The invention further relates to the use of these compounds as pharmaceutically active agents, as well as the use of the pharmaceutically active agents for the treatment of bacterial, neurodegenerative and tumor diseases.

Abstract: A lifting apparatus having a tool, which is vertically displaceable by means of a motor and to which at least a first toothed wheel is coupled in terms of movement. The toothed wheel engages over the vertical path of displacement in a stationary toothed rack. The lifting gear includes a safety device having a blocking element which, in a locked position, stops the tool from moving in the direction of gravity, at least when the lifting apparatus is deenergized, wherein the blocking element stops the tool over the vertical path of displacement, at basically any level in any vertical position, and is held against a restoring force in an unblocking position with vertical movement of the tool, and the restoring force pushes the blocking element into its locked position, at least when the lifting apparatus is deenergized.

Abstract: A rotor arm for an electrical machine having a support pot, which includes a hub for the mounting of a drive shaft, for mounting at least one magnetic element is provided. The rotor arm includes a supporting disk arranged on a support pot at a distance axially from the hub. The supporting element has a passage aligned with the hub for mounting the drive shaft.

Abstract: A rotor arm for an electrical machine includes a support pot for mounting a magnetic element. The support pot has a hub bearing a drive shaft. An inner peripheral surface of the rotor arm has, in an axial direction from the hub, an end stop for a supporting element of the rotor arm for the further bearing of the drive shaft.

Abstract: The present invention relates to an in vitro or ex vivo method of preparing a cell-free composition, said method comprising or consisting of (a) subjecting cells to stress; and (b) collecting factors produced, preferably secreted by said cells when subjected to said stress, thereby obtaining said cell-free composition; wherein said cells are comprised in or form at least one first carrier and said collecting is effected by means of at least one second carrier which second carrier(s) is/are cell-free and concomitantly present with and spatially distinct from said first carrier; and said collecting is effected using a device comprising or consisting of (i) said first carrier(s) which first carrier(s) comprise(s) said cells or is/are suitable to hold said cells; (ii) said second carrier(s) which is cell-free; and (iii) means of subjecting said cells in said first carrier to stress; wherein first carrier(s) and second carrier(s) are positioned such that factors secreted by said cells when subjected to stress are

Abstract: The invention relates to compounds that can be used, in particular, as structural mimetics of proline-rich peptides and are correspondingly able to bond with proline-rich-motif binding domains (PRM domains) of proteins. The invention further relates to the use of these compounds as pharmaceutically active agents, as well as the use of the pharmaceutically active agents for the treatment of bacterial, neurodegenerative and tumor diseases.

Abstract: The present invention provides acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes which can deliver carbon monoxide to a physiological target, wherein release of carbon monoxide can be enzymatically-triggered. The present invention also provides for methods of manufacturing the enzymatically-triggered carbon monoxide releasing molecules and methods for their use.

Abstract: In the heat utilization installation (1) according to the invention several heat sources (2) are included which are provided each with a jet pump (16), (17), (18), (19). The heat sources (2) are connected to a heat carrier circuit system (7) which includes a single, central circulating pump or circulating pump unit (20). The individual jet pumps (16) to (19) are so controlled for the respective heat sources (2), the required operating temperatures with respect to temperature difference between the outlet and inlet and the flow volume are maintained or achieved. With the possibility of independent control of the flow volumes at the various heat sources (2), uniform fluid temperatures as required for a buffer store (22) or heat consumers can be maintained.

Abstract: Substituted tricyclic diproline analogues of the formula (I): wherein the variables are as defined herein. Also disclosed are methods for the production thereof, the use thereof for the induction of an alpha-helix conformation in peptides and/or proteins, pharmaceuticals containing said compounds, methods for the production of a peptide library containing said compounds, and peptide libraries containing said compounds.