Patents by Inventor Hans-Heinrich Hoffmann

Hans-Heinrich Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds and uses thereof
    Patent number: 9096585
    Abstract: Described herein are Compounds, compositions comprising such Compounds, and the use of such Compounds and compositions as anti-viral agents. In one aspect, provided herein are methods of inhibiting viral replication using Compounds described herein or compositions thereof. In another aspect, provided herein are methods for preventing a symptom of a viral infection using a Compound, or a composition thereof. In another aspect, provided herein are methods of treating and/or managing viral infection using a compound or a composition thereof.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: August 4, 2015
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Megan Shaw, Hans-Heinrich Hoffmann, Adolfo Garcia-Sastre, Peter Palese
  • Compounds that modulate negative-sense, single-stranded RNA virus replication and uses thereof
    Patent number: 8629283
    Abstract: The present invention relates to compounds that modulate the replication of negative-sense, single-stranded RNA viruses, such as influenza virus, and the use of such compounds. The invention relates to methods for increasing the titer of negative-sense, single-stranded RNA viruses, such as influenza virus, in substrates for virus propagation (e.g., tissue culture). The invention also relates to the use of compounds that decrease virus replication as antiviral agents. The invention further relates to methods for identifying compounds that modulate the replication of negative-sense, single-stranded RNA viruses, in particular, influenza virus.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: January 14, 2014
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Megan L. Shaw, Hans-Heinrich Hoffmann, Adolfo Garcia-Sastre, Peter Palese
  • Antiviral Compounds and Uses Thereof
    Publication number: 20130137678
    Abstract: Described herein are Compounds, compositions comprising such Compounds, and the use of such Compounds and compositions as anti-viral agents. In one aspect, provided herein are methods of inhibiting viral replication using Compounds described herein or compositions thereof. In another aspect, provided herein are methods for preventing a symptom of a viral infection using a Compound, or a composition thereof. In another aspect, provided herein are methods of treating and/or managing viral infection using a compound or a composition thereof.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 30, 2013
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: Megan Shaw, Hans-Heinrich Hoffmann, Adolfo Garcia-Sastre, Peter Palese
  • COMPOUNDS THAT MODULATE NEGATIVE-SENSE, SINGLE-STRANDED RNA VIRUS REPLICATION AND USES THEREOF
    Publication number: 20110105423
    Abstract: The present invention relates to compounds that modulate the replication of negative-sense, single-stranded RNA viruses, such as influenza virus, and the use of such compounds. The invention relates to methods for increasing the titer of negative-sense, single-stranded RNA viruses, such as influenza virus, in substrates for virus propagation (e.g., tissue culture). The invention also relates to the use of compounds that decrease virus replication as antiviral agents. The invention further relates to methods for identifying compounds that modulate the replication of negative-sense, single-stranded RNA viruses, in particular, influenza virus.
    Type: Application
    Filed: March 6, 2009
    Publication date: May 5, 2011
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
    Inventors: Megan L Shaw, Hans-Heinrich Hoffmann, Adolfo Garcia-Sastre, Peter Palese