Patents by Inventor Hans-Hermann Lau

Hans-Hermann Lau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6303792
    Abstract: The invention relates to a process for obtaining N-(4-trifluoromethylphenyl)-5-methyl-isoxazole-4-carboxamide in crystalline form, which is essentially free of byproducts. For this purpose, N-(4-trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide is transferred into an organic solvent or into mixtures of organic solvents and water, the amount of byproduct in the solution is determined by quantitative analysis and an equimolar amount of a base is added. N-(4-Trifluoromethylphenyl)-5-methyl-isoxazole-4-carboxamide is isolated from the resulting solution by crystallization.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: October 16, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Hans-Hermann Lau, Udo Hedtmann, Holger Faasch, Andreas Gappisch
  • Patent number: 4914127
    Abstract: 3-Demethylmevalonic acid derivatives of the formula I (.delta.-lactone) and Ia (corresponding dihydroxycarboxylic acid derivative) ##STR1## in which A-B, Z, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the indicated meanings, a process for the preparation of these compounds, their use as medicaments and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I and Ia are described.
    Type: Grant
    Filed: March 8, 1989
    Date of Patent: April 3, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Beck, Bela Kerekjarto, Hans-Hermann Lau, Gunther Wess
  • Patent number: 4898868
    Abstract: 3-Demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on these compounds, the use thereof, and intermediates3-Demethyl-4-fluoromevalonic acid derivatives of the formula I, and the corresponding dihydroxy carboxylic acid derivatives of the formula II ##STR1## in which R, X and Y have the stated meanings, processes for the preparation of these compounds, the use thereof as medicaments, and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I and formula II are described.
    Type: Grant
    Filed: July 8, 1988
    Date of Patent: February 6, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Andreas Bergmann, Wilhelm Bartmann, Gerhard Beck, Hans-Hermann Lau
  • Patent number: 4778817
    Abstract: Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2 and Y have the indicated meanings, their physiologically tolerated acid addition salts, and a process for the preparation of these compounds are described. The compounds inhibit thromboxane synthetase and can thus be used as medicaments.
    Type: Grant
    Filed: March 11, 1986
    Date of Patent: October 18, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Hermann Lau, Wilhelm Bartmann, Gerhard Beck, Gunther Wess
  • Patent number: 4745120
    Abstract: The present invention relates to new pyridines substituted in the 3-position, of the formula ##STR1## and to a process for their preparation. The compounds bring about specific inhibition of thromboxane synthetase and can thus be used as medicaments.
    Type: Grant
    Filed: August 21, 1985
    Date of Patent: May 17, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gunther Wess, Wilhelm Bartmann, Gerhard Beck, Hans-Hermann Lau
  • Patent number: 4734406
    Abstract: Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and Y have the indicated meanings, their physiologically tolerated acid addition salts, and a process for the preparation of these compounds, are described. The compounds inhibit thromboxane synthetase and can thus be used as medicaments.
    Type: Grant
    Filed: March 11, 1986
    Date of Patent: March 29, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Hermann Lau, Wilhelm Bartmann, Gerhard Beck, Gunther Wess
  • Patent number: 4665080
    Abstract: The present invention relates to new ortho-, meta- and para-substituted imidazolylmethylstyrenes of the formula I ##STR1## and to a process for their preparation. The compounds according to the invention are distinguished by having a specific inhibitory effect on the synthesis of thromboxane, and hence they can be used as medicaments.
    Type: Grant
    Filed: July 3, 1985
    Date of Patent: May 12, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gunther Wess, Wilhelm Bartmann, Gerhard Beck, Hans-Hermann Lau
  • Patent number: 4611000
    Abstract: The present invention relates to 5-substituted .DELTA.2-imidazolinyl-thioethers and to intermediates and processes for their preparation. The components according to the invention are distinguished in particular by their platelet aggregation-inhibiting and hypotensive action.
    Type: Grant
    Filed: October 11, 1984
    Date of Patent: September 9, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Beck, Wilhelm Bartmann, Hans-Hermann Lau, Gunther Wess
  • Patent number: 4610999
    Abstract: The present invention relates to 4-substituted .DELTA.2-imidazolinyl-thioethers and to intermediates and processes for their preparation. The components according to the invention are distinguished in particular by their platelet aggregation-inhibiting and hypotensive action.
    Type: Grant
    Filed: October 11, 1984
    Date of Patent: September 9, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Beck, Wilhelm Bartmann, Hans-Hermann Lau, Gunther Wess