Patents by Inventor Hans J. Enenkel

Hans J. Enenkel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-arylimidazopyridines
    Patent number: 5104881
    Abstract: New 2-arylimidazopyridines of the general formula I ##STR1## wherein --A.dbd.B-- is (a) --CH.dbd.N-- or (b) N.dbd.CH--,Ar is a phenyl radical, which, in case (a), is substituted by one or two alkynyloxy, cyanomethoxy, carboxymethoxy, and/or alkyloxycarbonylmethoxy groups, and can be substituted by one or two additional hydroxyl, alkyloxy, alkenyloxy and/or alkynyloxy groups, or which in case (b), is substituted by one to three hydroxyl, mercapto, and/or --Z--R groups, Z is --O--, --S-- or --SO-- andR is alkyl, alkenyl, alkynyl, hydroxyalkyl, cyanomethyl, carboxymethyl or alkyloxycarbonylmethyl, the alkyl, alkenyl, alkynyl and hydroxyalkyl groups each having up to 5 C atoms, but wherein in case (b), the phenyl radical is only substituted by hydroxyl or methoxy groups if it has at the same time at least one other substituent differing from these,and their physiologically acceptable salts show positive inotropic effects.
    Type: Grant
    Filed: March 29, 1984
    Date of Patent: April 14, 1992
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rochus Jonas, Klaus Minck, Hans J. Enenkel, Hans-Jochen Schliep
  • Pharmaceutical compositions for treating ulcers containing 2-aryltetraazaindenes
    Patent number: 4654344
    Abstract: 2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CN.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or tri-substituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologically acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: March 31, 1987
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Rochus Jonas, Michael Kloft, Hanns Wurziger, Juergen Harting, Hans J. Enenkel, Klaus-Otto Minck, Hans-Jochen Schliep
  • Pharmaceutical compositions containing 2-aryltetraazaindenes for treating ulcers or cardiac insufficiency or blood pressure abnormalities
    Patent number: 4575505
    Abstract: 2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CH.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or trisubstituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologially acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.
    Type: Grant
    Filed: July 26, 1984
    Date of Patent: March 11, 1986
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rochus Jonas, Michael Kloft, Hanns Wurziger, Jurgen Harting, Hans J. Enenkel, Klaus-Otto Minck, Hans-Jochen Schliep
  • 2-Aryltetraazaindenes for treating cardiac insufficiency
    Patent number: 4477454
    Abstract: 2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CH.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or tri-substituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologically acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.
    Type: Grant
    Filed: May 9, 1983
    Date of Patent: October 16, 1984
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Rochus Jonas, Michael Kloft, Hanns Wurziger, Juergen Harting, Hans J. Enenkel, Klaus-Otto Minck, Hans-Jochen Schliep