Abstract: A reconfigurable capillary liquid chromatography system includes a solvent delivery manager including a first solvent pump assembly including a first pump housing or mount. A base module is further provided including a base module housing which is user accessible, or a base module bracket, and an injection valve for sample injection to a liquid chromatography column. The injection valve has an inlet port for receiving a sample and the injection valve is mounted in or on the base module housing or the base module bracket. The solvent delivery manager is configured to deliver solvent to the injection valve. A reconfigurable control system is also provided for controlling the reconfigurable capillary liquid chromatography system.

Abstract: A solid phase microextraction substrate is disclosed. The solid phase microextraction substrate has a sorbent coating on at least part of a surface thereof. The coating is adapted for extracting at least one analyte component from a fluid matrix. The coating includes sorbent particles in a polymeric adhesive matrix. A majority of pores in each sorbent particle in the coating do not contain substantially any of the polymeric adhesive matrices.