Patents by Inventor Hans Jakob Kristoffer FAMM
Hans Jakob Kristoffer FAMM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240066299Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.Type: ApplicationFiled: February 1, 2023Publication date: February 29, 2024Inventors: Silvia Margarida Vilares Santos Conde, Daniel John Chew, Hans Jakob Kristoffer Famm, Maria Pedro Sucena Guarino, Brad Holinski, Sonal Patel
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Patent number: 11577080Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.Type: GrantFiled: November 3, 2015Date of Patent: February 14, 2023Assignees: Presidio Medical, Inc., Faculdade De Ciências Médicas Da Universidade Nova De LisboaInventors: Silvia Margarida Vilares Santos Conde, Daniel John Chew, Hans Jakob Kristoffer Famm, Maria Pedro Sucena Guarino, Brad Holinski, Sonal Patel
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Patent number: 11571574Abstract: Modulation of neural activity in the superior laryngeal nerve (SLN) or cervical sympathetic trunk (CST) is effective in treating diseases and conditions mediated by thyroid and parathyroid hormones, in particular diseases associated with calcitonin secretion (e.g. osteoporosis) or diseases associated with thyroxine secretion (e.g. hypothyroid syndrome).Type: GrantFiled: November 10, 2017Date of Patent: February 7, 2023Assignees: GALVANI BIOELECTRONICS LIMITED, TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGYInventors: Hans Jakob Kristoffer Famm, Harumi Hotta, Arun Sridhar
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Publication number: 20210393949Abstract: The invention provides devices, apparatuses, systems and methods for treating and ameliorating inflammation of the gut. In particular, the invention provides devices, apparatuses and methods in which a neuromodulatory signal is delivered a splenic nerve and/or superior mesenteric plexus (SMP). The signal is able to treat inflammatory disorders, e.g., colitis, for example in Inflammatory Bowel Disease.Type: ApplicationFiled: February 26, 2021Publication date: December 23, 2021Applicants: GALVANI BIOELECTRONICS LIMITED, ACADEMISCH MEDISCH CENTRUMInventors: Daniel John CHEW, Wouter Jacob DE JONGE, Hans Jakob Kristoffer FAMM, Sonal PATEL, Olaf WELTING
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Patent number: 10974041Abstract: The invention provides devices, apparatuses, systems and methods for treating and ameliorating inflammation of the gut. In particular, the invention provides devices, apparatuses and methods in which a neuromodulatory signal is delivered a splenic nerve and/or superior mesenteric plexus (SMP). The signal is able to treat inflammatory disorders, e.g., colitis, for example in Inflammatory Bowel Disease.Type: GrantFiled: April 22, 2016Date of Patent: April 13, 2021Assignees: GALVANI BIOELECTRONICS LIMITED, ACADEMISCH MEDISCH CENTRUMInventors: Daniel John Chew, Wouter Jacob De Jonge, Hans Jakob Kristoffer Famm, Sonal Patel, Olaf Welting
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Patent number: 10406362Abstract: Methods for treating polycystic ovarian syndrome with a neuromodulation device that modulates sympathetic neural activity are described herein. The neuromodulation device is an apparatus for the treatment of polycystic ovarian syndrome. In one aspect, the apparatus decreases the neural activity of a postganglionic ovary-innervating sympathetic nerve. Modulation in neural activity may be achieved using an apparatus comprising one or more stimulators each configured to apply a signal to a postganglionic ovary-innervating sympathetic nerve of the patient, a controller coupled to the one or more stimulators, the controller controlling the signal to be applied by each of the one or more stimulators, such that the signal decreases the neural activity of the nerve to produce a physiological and/or biochemical response in the patient, wherein the physiological and/or biochemical response comprises an improvement in one or more symptoms of polycystic ovarian syndrome.Type: GrantFiled: February 19, 2016Date of Patent: September 10, 2019Assignee: Galvani Bioeletronics LimitedInventors: Hans Jakob Kristoffer Famm, Hernan E. Lara, Victor Eugene Pikov, Arun Sridhar
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Publication number: 20190262613Abstract: Modulation of neural activity in the superior laryngeal nerve (SLN) or cervical sympathetic trunk (CST) is effective in treating diseases and conditions mediated by thyroid and parathyroid hormones, in particular diseases associated with calcitonin secretion (e.g. osteoporosis) or diseases associated with thyroxine secretion (e.g. hypothyroid syndrome).Type: ApplicationFiled: November 10, 2017Publication date: August 29, 2019Applicants: Galvani Bioelectronics Limited, Tokyo Metropolitan Institute of GerontologyInventors: Hans Jakob Kristoffer FAMM, Harumi HOTTA, Arun SRIDHAR
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Publication number: 20180214691Abstract: The present invention provides improved devices, systems and methods to provide for control of bladder function. Aspects of the present disclosure relate to an apparatus, system and/or a method for modulating the neural activity of afferent fibres of the pelvic nerve to bladder function. In one aspect, the disclosure relates to the use of pharmaceutical compositions in patients undergoing neuromodulation therapy.Type: ApplicationFiled: August 3, 2016Publication date: August 2, 2018Applicants: GALVANI BIOELECTRONICS LIMITED, DUKE UNIVERSITYInventors: Hans Jakob Kristoffer FAMM, Warren Murray GRILL, James Arthur HOKANSON, Christopher Lawrence LANGDALE, Arun SRIDHAR
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Publication number: 20180117319Abstract: The invention provides devices, apparatuses, systems and methods for treating and ameliorating inflammation of the gut. In particular, the invention provides devices, apparatuses and methods in which a neuromodulatory signal is delivered a splenic nerve and/or superior mesenteric plexus (SMP). The signal is able to treat inflammatory disorders, e.g., colitis, for example in Inflammatory Bowel Disease.Type: ApplicationFiled: April 22, 2016Publication date: May 3, 2018Applicants: GALVANI BIOELECTRONICS LIMITED, ACADEMISCH MEDISCH CENTRUMInventors: Daniel John CHEW, Wouter Jacob DE JONGE, Hans Jakob Kristoffer FAMM, Sonal PATEL, Olaf WELTING
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Publication number: 20180043155Abstract: The present invention relates to medical devices and, more particularly, to medical devices that deliver neuromodulating therapy.Type: ApplicationFiled: February 19, 2016Publication date: February 15, 2018Applicants: GALVANI BIOELECTRONICS LIMITED, HUNTINGTON MEDICAL RESEARCH INSTITUTES, UNIVERSITY OF CHILIInventors: Hans Jakob Kristoffer FAMM, Hernan E. LARA, Victor Eugene PIKOV, Arun SRIDHAR
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Publication number: 20170333708Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.Type: ApplicationFiled: November 3, 2015Publication date: November 23, 2017Applicants: GALVANI BIOELECTRONICS LIMITED, FACULDADE DE CIÊNCIAS MÉDICAS DA UNIVERSIDADA NOVA DE LISBOAInventors: Silvia Margarida Vilares Santos CONDE, Daniel John CHEW, Hans Jakob Kristoffer FAMM, Maria Pedro Sucena GUARINO, Brad HOLINSKI, Sonal PATEL