Abstract: A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.

Abstract: A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.

Abstract: Nucleoside-5′-triphosphates and phosphoramidites which carry a residue absorbing in the long wavelength region, preferably a carbocyanine group of the general formula (I), on the base portion or on the phosphorus atom in which R1 and R2 each denote hydrogen or together form a phenyl residue; R3 denotes hydrogen if linkage with the nucleotide is via the R4 position or it denotes a —NHCS— group if linkage with the nucleotide is via the R3 position; both R4 and R5, or R5, alone denote an alkylsulfonyl group with n being a number from 3 to 5 or R4 represents a —NHCS— group with n being a number from 3 to 8, as well as the use of the compounds to label, detect and sequence nucleic acids.

Abstract: Image recording system for the evaluation of analytical test elements with a holding unit (8) into which the test elements are placed or onto which they are placed as well as a lens system (5) which records an image of the test elements on a CCD chip (3) and an evaluation unit that evaluates the image on the CCD chip or displays it on a monitor. The image recording system enables numerous test elements of different sizes to be evaluated at different wavelengths without requiring focussing by the user. The lens system used for this is a reducing optical system with an aperture on the side of the image of at least 0.7 and a distance between the CCD chip and the nearest lens of the lens system of less than 15 mm. In addition the distance between the nearest lens of the lens system and the CCD chip is kept constant to at least 10 &mgr;m in order to ensure an adequate sharpness. A compensator is described for keeping this distance constant.

Abstract: Stable enzyme compositions are provided in a liquid form for the enzymatic radioactive and non-radioactive labelling of nucleic acids and oligonucleotides. The mixtures preferably contain 30-60% (v/v) glycerin. At a storage temperature between -20 .degree. C. and +4 .degree. C. over a period of at least 12 months, the mixtures do not exhibit any loss of activity.