Patents by Inventor Hans-Joerg Warnatz

Hans-Joerg Warnatz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for linking and characterising linked nucleic acids, E.G. antibody encoding nucleic acids, in a composition
    Patent number: 9631214
    Abstract: The invention relates to a method for linking at least two target nucleic acid molecules from a single biological compartment, comprising the steps of isolating a fraction from a sample, wherein the fraction comprises the compartment comprising at least two nucleic acid molecules, diluting the fraction and aliquoting the dilution in multiple separate reaction vessels such that each reaction vessel comprises preferably one compartment, or encapsulating the compartment in emulsion droplets such that each droplet comprises preferably one compartment; linking the at least two target nucleic acid molecules, preferably by overlap extension PCR. The method may be employed in the analysis of mutations present in a single cell and in the production of antibodies which are present in a single hybridoma.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: April 25, 2017
    Assignees: Max-Planck Gesellschaft Zur Foerderung Der Wissenschaften E.V., Alaeris Theranostics GmbH
    Inventors: Hans-Joerg Warnatz, Joern Gloekler, Hans Lehrach
  • METHOD FOR LINKING AND CHARACTERISING LINKED NUCLEIC ACIDS, E.G. ANTIBODY ENCODING NUCLEIC ACIDS, IN A COMPOSITION
    Publication number: 20150004618
    Abstract: The invention relates to a method for linking at least two target nucleic acid molecules from a single biological compartment, comprising the steps of isolating a fraction from a sample, wherein the fraction comprises the compartment comprising at least two nucleic acid molecules; diluting said fraction and aliquoting the dilution in multiple separate reaction vessels such that each reaction vessel comprises preferably one compartment, or encapsulating said compartment in emulsion droplets such that each droplet comprises preferably one compartment; linking said at least two target nucleic acid molecules, preferably by overlap extension PCR. The method may be employed in the analysis of mutations present in a single cell and in the production of antibodies which are present in a single hybridoma.
    Type: Application
    Filed: February 6, 2013
    Publication date: January 1, 2015
    Applicant: MAX-PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Hans-Joerg Warnatz, Joern Gloekler, Hans Lehrach