Abstract: An endoscopy device and a method of manufacturing an endoscopy device are disclosed. The endoscopy device comprises: a body having a handle portion and a housing portion, the housing portion having an outlet; a switching mechanism disposed in the housing portion; a rigid outer tube detachably coupled to the housing portion at the outlet, and a flexible inner tube extendable from the outer tube, wherein the switching mechanism is configured to retract or extend the inner tube outwardly through the outer tube.

Abstract: Certain exemplary aspects of the present disclosure are directed towards apparatuses and methods which autonomously decontaminate parts. Parts to be cleaned are identified, and based on the identification of the part, a part specific cleaning program is initiated. During the cleaning, the part is manipulated about a gas supply in such a way that the drag force on the contamination particles attached to the part exceeds the contamination particles' surface adhesion force and accordingly is removed from the surface of the part. The removed contamination is then evacuated from the atmospheric environment near the part by a low pressure zone of a second gaseous material near the part.

Abstract: Certain exemplary aspects of the present disclosure are directed towards apparatuses and methods which autonomously decontaminate parts. Parts to be cleaned are identified, and based on the identification of the part, a part specific cleaning program is initiated. During the cleaning, the part is manipulated about a gas supply in such a way that the drag force on the contamination particles attached to the part exceeds the contamination particles' surface adhesion force and accordingly is removed from the surface of the part. The removed contamination is then evacuated from the atmospheric environment near the part by a low pressure zone of a second gaseous material near the part.

Abstract: Certain exemplary aspects of the present disclosure are directed towards apparatuses and methods which autonomously decontaminate parts. Parts to be cleaned are identified, and based on the identification of the part, a part specific cleaning program is initiated. During the cleaning, the part is manipulated about a gas supply in such a way that the drag force on the contamination particles attached to the part exceeds the contamination particles' surface adhesion force and accordingly is removed from the surface of the part. The removed contamination is then evacuated from the atmospheric environment near the part by a low pressure zone of a second gaseous material near the part.

Abstract: Certain exemplary aspects of the present disclosure are directed towards apparatuses and methods which autonomously decontaminate parts. Parts to be cleaned are identified, and based on the identification of the part, a part specific cleaning program is initiated. During the cleaning, the part is manipulated about a gas supply in such a way that the drag force on the contamination particles attached to the part exceeds the contamination particles' surface adhesion force and accordingly is removed from the surface of the part. The removed contamination is then evacuated from the atmospheric environment near the part by a low pressure zone of a second gaseous material near the part.

Abstract: A method for targeting a therapeutic agent to a target site in a patient is provided.

Abstract: The targeting capability of an antibody is enhanced using an antibody-enzyme conjugate and a separate soluble substrate-agent conjugate, wherein the targeted enzyme catalyzes the conversion of a soluble substrate, bearing at least one therapeutic or diagnostic agent, to a product comprising the agent, which accumulates at the target site for effective treatment or diagnosis. This method is useful for targeting any type of agent to a site to which an antibody can selectively bind, including use for imaging, e.g., tumors, infectious lesions, fibrin clots, myocardial infarctions, non-cancerous cells, damaged normal cells, atherosclerotic plaque, lymphocyte autoreactive clones, and for therapy, e.g., with drugs, toxins, immune modulators, radioisotopes or antibiotics.

Abstract: A polyspecific anti-leukocyte antibody conjugate for targeting foci of leukocyte accretion comprises an immunoreactive polyspecific composite of at least two different substantially monospecific antibodies or antibody fragments, conjugated to at least one imaging agent, wherein at least two of said antibodies or antibody fragments specifically bind to different leukocyte cell types.A method for targeting an imaging agent to an inflammatory or infectious lesion comprises injecting a mammal parenterally with an effective amount for targeting of the above anti-leukocyte imaging conjugate.A therapeutic anti-leukocyte antibody-agent conjugate for targeting foci of leukocyte accretion comprises at least one immunoreactive substantially monospecific antibody or antibody fragment which specifically binds to at least one leukocyte cell type, conjugated to at least one therapeutic antimicrobial agent.

Abstract: A printing mechanism and a distributing roller unit thereof has an inking roller, a dampening roller, a distributing roller located between the inking roller and dampening roller and movable between at least two positions in which it becomes alternately associated with the inking roller and the dampening roller and axially displaceable relative to the inking roller and the dampening roller, respectively, and elements for moving the distributing roller between the two positions and axially displacing the same.

Abstract: To guarantee an exact engagement of toothed flanks in the driving gear train of a multi-color sheet-fed rotary printing machine, the gears in the train pertaining to the first printing unit of the machine are power supplied from a driving member which transmits a two-fold power portion in comparison to power portions transmitted by driving elements assigned to the remaining printing units.

Abstract: To guarantee an exact engagement of toothed flanks in the driving gear train of a multi-color sheet-fed rotary printing machine, the gears in the train pertaining to an intermediate printing unit of the machine are power supplied from a driving member which transmit a three-fold power portion in comparison to uniform power portions transmitted by driving elements assigned to the remaining printing units.

Abstract: In the ink dosage adjusting device comprising at least one motor-driven ink zone adjusting screw for adjusting the position of the doctor blade relative to the doctor roller wear of the blade is compensated for by an additional adjusting device without an electrical readjustment of an electrical measure value receiver. The additional adjusting device includes a rotatable sleeve through which the ink zone adjusting screw extends.

Abstract: Method and device for positioning application rollers and printing cylinders in the printing machine during the operation with reduced machine numbers of revolutions occuring during the slow-down operation, tipping operation or hand operation, in which a precise transmission of the torque to printing units and thus accurate development of predetermined angular rotation steps is possible due to the fact that a portion of the torque of the whole initial breakaway torque is applied directly to each individual printing unit and the remaining portion of the torque required for positioning of printing cylinders and application rollers is produced by an auxiliary drive.

Abstract: In a control system for a plurality of ink zone adjusters in a printing machine each adjuster is connected via a main control circuit and a first bidirectional address and data bus to an input and output unit where the measured data are stored on specific addresses to be retrieved for later use. An additional storage control circuit is connected to the first bidirectional data bus to provide an intermediate storage of the measured or retrieved data. The addtional storage control circuit includes an addressing circuit controlled by a program control circuit to apply addresses pertaining to individual printing units to corresponding storing circuits.

Abstract: A moistening system for a printing machine, which can be suitable for application to a printing roller either of a wetting agent or alcohol, comprises a fountain roller partially immersed in a reservoir containing an agent to be applied to the printing roller, a slip roller in contact with the fountain roller, a rubbing cylinder rotated with the speed of the printing machine and applying the agent to the impression roller through distributing rollers, and a vibrating roller interpositioned between the rubbing roller and the slip roller to transmit the agent from the slip roller to the rubbing roller. The slip roller is connected to the rubbing roller so that they rotate with the same velocity.

Abstract: A printing press is provided with a safety device mounted in the vicinity of a gap formed between two counter printing rollers for preventing the gap from intrusion by foreign elements, such as a mop or the hand of an operator. The device includes a four-link transmission unit operatively interconnected between pivotable guard plates and a cam switch adapted to actuate an end switch of the printing press to shut the latter off. The guard plates are swung away from the rollers so that the gap is enlarged.

Abstract: Disclosed is a control system for an ink blade of a printing machine provided with a series of key setting units each having a key position sensor and a key drive controlled by an adjusting device described in patent application Ser. No. 252,126. In order to achieve proper adjustment of marginal key setting units, there is provided a switching unit with a plurality of contacts assigned to respective key position measuring sensors and including additional switching contacts assigned to imaginary key position setting units adjoining the real setting units at each end of the ink zone. The additional marginal switching contacts are connected to the output of assigned sample-and-hold members which apply thereto the measured value from the extreme actual position sensors so that comparing differential transducer comparing the measured values of consecutive pairs of position sensors always produces a starting difference which does not exceed a predetermined limit value.

Abstract: A device for adjusting an ink knife relative to a ductor roller in an ink-applicator of a printing machine is disclosed. The device includes an number of adjusting arrangements arranged lengthwise of the ductor roller to control a plurality of ink zones along the length of the roller, each arrangement including a pivotable lever actuated to move a stripped edge of the ink knife to and from the ductor roller, and a tension spring extended somewhat normally to the ink knife and between the ink knife and a supporting element rigidly connected to the housing of the ink applicator, the tension spring locking the lever in its selected adjusted position. The device substantially reduces mutual influence of adjacent ink zones on each other during the adjusting operation.