Patents by Inventor Hans Kalkman

Hans Kalkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BENZISOXAZOLES
    Publication number: 20200131166
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: December 26, 2019
    Publication date: April 30, 2020
    Inventors: Joachim Nozulak, Hans Kalkman
  • BENZISOXAZOLES
    Publication number: 20190276444
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: May 28, 2019
    Publication date: September 12, 2019
    Inventors: Joachim Nozulak, Hans Kalkman
  • BENZISOXAZOLES
    Publication number: 20190055228
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 21, 2019
    Inventors: Joachim Nozulak, Hans Kalkman
  • Hematological analyzer, method for analyzing body fluid and computer program product
    Patent number: 10168320
    Abstract: A hematological analyzer for measuring blood, sets a body fluid measurement mode; receives a measurement start instruction; irradiates a measurement sample with light and obtains optical information from cells contained in the measurement sample; and classifies at least white blood cells and nucleated cells other than white blood cells contained in the measurement sample, and counts the white blood cells and nucleated cells other than white blood cells based on the optical information obtained from the cells in the measurement sample prepared from a body fluid sample and white blood cell measuring reagent when the body fluid measurement mode has been set and the measurement start instruction has been selected, is disclosed. A method for analyzing body fluid and a computer program product are also disclosed.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: January 1, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Takaaki Nagai, Noriyuki Narisada, Hans Kalkman
  • BENZISOXAZOLES
    Publication number: 20180118729
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: November 24, 2017
    Publication date: May 3, 2018
    Inventors: Joachim Nozulak, Hans Kalkman
  • BENZISOXAZOLES
    Publication number: 20170129878
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: January 20, 2017
    Publication date: May 11, 2017
    Inventors: Joachim Nozulak, Hans Kalkman
  • HEMATOLOGICAL ANALYZER, METHOD FOR ANALYZING BODY FLUID AND COMPUTER PROGRAM PRODUCT
    Publication number: 20140356903
    Abstract: A hematological analyzer for measuring blood, sets a body fluid measurement mode; receives a measurement start instruction; irradiates a measurement sample with light and obtains optical information from cells contained in the measurement sample; and classifies at least white blood cells and nucleated cells other than white blood cells contained in the measurement sample, and counts the white blood cells and nucleated cells other than white blood cells based on the optical information obtained from the cells in the measurement sample prepared from a body fluid sample and white blood cell measuring reagent when the body fluid measurement mode has been set and the measurement start instruction has been selected, is disclosed. A method for analyzing body fluid and a computer program product are also disclosed.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Applicant: SYSMEX CORPORATION
    Inventors: Takaaki NAGAI, Noriyuki NARISADA, Hans KALKMAN
  • Hematological analyzer, method for analyzing body fluid and computer program product
    Patent number: 8841117
    Abstract: A hematological analyzer for measuring blood, sets a body fluid measurement mode; receives a measurement start instruction; irradiates a measurement sample with light and obtains optical information from cells contained in the measurement sample; and classifies at least white blood cells and nucleated cells other than white blood cells contained in the measurement sample, and counts the white blood cells and nucleated cells other than white blood cells based on the optical information obtained from the cells in the measurement sample prepared from a body fluid sample and white blood cell measuring reagent when the body fluid measurement mode has been set and the measurement start instruction has been selected, is disclosed. A method for analyzing body fluid and a computer program product are also disclosed.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: September 23, 2014
    Assignee: Sysmex Corporation
    Inventors: Takaaki Nagai, Noriyuki Narisada, Hans Kalkman
  • Blood cell analyzer, blood cell analyzing method, and computer program product
    Patent number: 8017078
    Abstract: A blood cell analyzer is provided with a first detection unit for electrically detecting blood cells in blood sample; a second detection unit for optically detecting blood cells in blood sample; a volume information obtainer for obtaining volume information of red blood cells based on the electrically detected blood cells; a scattered light intensity information obtainer for obtaining a scattered light intensity of red blood cells based on the optically detected blood cells; a first histogram preparer for preparing a first histogram of the volume information of each of red blood cells; a second histogram preparer for preparing a second histogram of the scattered light intensity information of each of red blood cells; a display unit; and a data processor for preparing a screen for displaying on the display unit, the screen including the first and second histograms.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: September 13, 2011
    Assignee: Sysmex Corporation
    Inventors: Jo Linssen, Hans Kalkman
  • Blood cell analyzer, blood cell analyzing method, and computer program product
    Publication number: 20080199947
    Abstract: A blood cell analyzer is provided with a first detection unit for electrically detecting blood cells in blood sample; a second detection unit for optically detecting blood cells in blood sample; a volume information obtainer for obtaining volume information of red blood cells based on the electrically detected blood cells; a scattered light intensity information obtainer for obtaining a scattered light intensity of red blood cells based on the optically detected blood cells; a first histogram preparer for preparing a first histogram of the volume information of each of red blood cells; a second histogram preparer for preparing a second histogram of the scattered light intensity information of each of red blood cells; a display unit; and a data processor for preparing a screen for displaying on the display unit, the screen including the first and second histograms.
    Type: Application
    Filed: December 19, 2007
    Publication date: August 21, 2008
    Inventors: Jo Linssen, Hans Kalkman
  • HEMATOLOGICAL ANALYZER, METHOD FOR ANALYZING BODY FLUID AND COMPUTER PROGRAM PRODUCT
    Publication number: 20080187951
    Abstract: A hematological analyzer for measuring blood, sets a body fluid measurement mode; receives a measurement start instruction; irradiates a measurement sample with light and obtains optical information from cells contained in the measurement sample; and classifies at least white blood cells and nucleated cells other than white blood cells contained in the measurement sample, and counts the white blood cells and nucleated cells other than white blood cells based on the optical information obtained from the cells in the measurement sample prepared from a body fluid sample and white blood cell measuring reagent when the body fluid measurement mode has been set and the measurement start instruction has been selected, is disclosed. A method for analyzing body fluid and a computer program product are also disclosed.
    Type: Application
    Filed: January 31, 2008
    Publication date: August 7, 2008
    Applicant: SYSMEX CORPORATION
    Inventors: Takaaki NAGAI, Noriyuki Narisada, Hans Kalkman
  • NEW USE OF ILOPERIDONE
    Publication number: 20080103177
    Abstract: The invention relates to the use of iloperidone in the treatment of affective disorders, including bipolar mood disorders.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 1, 2008
    Inventor: Hans Kalkman
  • Benzisoxazoles
    Publication number: 20070197595
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: September 30, 2004
    Publication date: August 23, 2007
    Inventors: Joachim Nozulak, Hans Kalkman
  • Combinations comprising ampa receptor antagonists for the treatment of schizophrenia
    Publication number: 20070082873
    Abstract: The present invention relates to combinations suitable for the treatment of psychiatric/neurological disorders, in particular schizophrenia. The combinations comprise at least one AMPA receptor antagonist and at least one compound selected from the group consisting of (a) anti-epileptic drugs selected from barbiturates and derivatives thereof, benzodiazepines, carboxamides, hydantoins, succinimides, valproic acid and other fatty acid derivates and other anti-epileptic drugs, (b) conventional antipsychotics and (c) atypical antipsychotics.
    Type: Application
    Filed: October 27, 2004
    Publication date: April 12, 2007
    Inventors: Kurt Lingenhöhl, Ference Martenyi, Silvio Ofner, Mary Karolchyk, Hans Kalkman
  • Substituted aminoalkanephosphonic acids
    Publication number: 20060293282
    Abstract: The present invention relates the use of substituted aminoalkanephosphonic acids in treating neuropathic pain, affective and attention disorders, schizophrenia, tinnitus, myopia and other ocular disorders.
    Type: Application
    Filed: April 29, 2003
    Publication date: December 28, 2006
    Inventors: Kurt Lingenhohl, Yves Auberson, Alyson Fox, Hans Neijt, Hans Kalkman
  • New use of iloperidone
    Publication number: 20060205786
    Abstract: The invention provides the use of iloperidone in the treatment of affective disorders including bipolar mood disorders.
    Type: Application
    Filed: May 4, 2006
    Publication date: September 14, 2006
    Inventor: Hans Kalkman
  • Optical isomers of an iloperidone metabolite
    Publication number: 20050020632
    Abstract: The invention provides compounds of formulae (I) and (II), their preparation and their use as pharmaceuticals.
    Type: Application
    Filed: August 30, 2002
    Publication date: January 27, 2005
    Inventors: Dominique Grimler, Hans Kalkman, Hegun Yin