Abstract: Solid drug formulations for oral administration containing one or more dihydropyridines in doses of between 10 and 240 mg and suitable to be administered as a single dose per day for the treatment of circulatory disorders and high blood pressure.

Abstract: An improved form of administration of 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridine-dicarboxylic acid-dimethylester (i.e., Nifedipine) is provided in which the Nifedipine is molecularly dispersed wihtin a solidified melt of polyethylene glycols which are liquid, semi-solid and solid at room temperature. The weight ratio of liquid to non-liquid polyethylene glycols in the solidified melt ranges from about 7:23 to 23:7, the solidification temperature of the mixture ranges from about 25.degree. C. to 62.degree. C. and the mixture has a viscosity of from about 1 to 180,000 poise when measured at 20.degree. C. in admixture with up to about 40 percent by weight of water.

Abstract: A pharmaceutical combination preparation and method for the treatment of circulatory disturbances comprising a dihydropyridine of the formula ##STR1## in which --R.sub.1, is a CH.sub.3 --O--CH.sub.2 --CH.sub.2 -- or CH.sub.3 group; R.sub.2 is a ##STR2## or CH.sub.3 --CH.sub.2 -- group; R.sub.3 is 4, NO.sub.2 or CL; and R.sub.2 is NO.sub.2, H or CL; and pharmaceutically suitable salts thereof; as active substance A and Pentoxifylline as active substance B, the quantity ratios of A:B being from about 1:150 to about 1:2.