Abstract: A teeth cleaning system that measures and analyzes analytes in a user's saliva. The system includes an actuated tray comprising brushing elements. At least one integrated sensor may be housed in a tray of said teeth cleaning system that can detect one or more analytes within said user's saliva. In operation, said integrated sensor is exposed to said user's saliva for measuring a concentration of said analyte in said user's saliva. An electrochemical analyzer and/or a processor may also be housed in a handle assembly for analyzing a signal related to at least one measuring of said concentration of said analyte. Said concentration readings and analysis may be sent to an external network, including a network that interfaces a mobile app for further analysis, presentation, or personalized advice and products sent to said user through said mobile app.