Patents by Inventor Hans Lennernas

Hans Lennernas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110222366
    Abstract: An injector device is disclosed, the injector device comprising an elongated mixing container extending along a first axis, and a piston member slidably positioned in the mixing container. The injector device comprises a mixing device comprising a mixing member, an elongated member parallel to the first axis and a handle member. The piston member comprises a piston head and a first locking arm flexibly connected to the piston head, such that the first locking arm in a first position extends substantially parallel to the elongated member and engages with the mixing device in such a way that the piston member moves in a first direction along the first axis with the mixing device. In a second position, the first locking arm may allow the mixing device to move relative to the mixing container independently of the piston member.
    Type: Application
    Filed: September 22, 2009
    Publication date: September 15, 2011
    Inventors: Niklas Axén, Hans Lennernäs, Johan Yngve, Lars Ake Malmsten, Gunilla Eketorp, Ake G. Pilbrant
  • Publication number: 20090118215
    Abstract: A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably for controlled-release of one or more therapeutically, prophylactically and/or diagnostically active substance. The method involves a concomitant step of hydrating and densifying a bioresorbable and hydratable ceramic such as calcium sulphate. The invention also relates to compositions comprising such a highly densified ceramic. The pharmaceutical composition is useful for targeted and controlled local prolonged release of active substances, e.g. anti-cancer agents, whereby the spectrum and severity of side effects are minimized due to an optimized local concentration-time profile.
    Type: Application
    Filed: March 14, 2007
    Publication date: May 7, 2009
    Applicant: Lidds AB
    Inventors: Hans Lennernas, Niklas Axen
  • Publication number: 20090036392
    Abstract: The present invention relates to a drug carrier composition comprising i) one or more biodegradable hydrating ceramics ii) one or more expandable agents, and iii) sorbed aqueous medium which in solid form has a ruptured structure. The function of the expandable agent is to create a ruptured structure in the solidified composition, either a foam-like structure or a disintegrated structure where it is split into a large number of parts, particles, units, granules or pieces, so as to obtain an enlarged apparent surface area that is exposed to degradation or erosion upon administration. Suitable substances to obtain this surface enlarging effect are gas-forming agents or swelling agents, gelling agents or disintegrants, here referred to as expandable agents. The expandable agents may be bioresorbable or non-bioresorbable.
    Type: Application
    Filed: October 21, 2004
    Publication date: February 5, 2009
    Applicant: LIDDS AB
    Inventors: Hans Lennernas, Bo Lennernas, Jonas Hugosson, Niklas Axen
  • Publication number: 20090035375
    Abstract: The present invention relates to glucocorticoid-containing pharmaceutical compositions or kits for use in acute emergency situations where acute glucocorticoid therapy is required. Notably, the invention relates to pharmaceutical compositions and kits that are designed to be administered by non-medically trained persons outside a hospital or another medical or clinical setting.
    Type: Application
    Filed: April 21, 2005
    Publication date: February 5, 2009
    Inventors: Stanko Skrtic, Jorgen Johnsson, Hans Lennernas, Thomas Hedner, Gudmundur Johannsson
  • Publication number: 20080286205
    Abstract: A method for treating prostate related diseases in a subject, the method comprising i) optionally administering to subject an initial boost dose of one or more active substances and/or prodrugs, and ii) administering locally into the prostate a controlled release pharmaceutical composition comprising one or more active substances in a biodegradable ceramic carrier. The biodegradable hydrating ceramic may be selected from the group consisting of non-hydrated or hydrated calcium sulphate, calcium phosphate, calcium carbonate, calcium fluoride, calcium silicate, magnesium sulphate, magnesium phosphate, magnesium carbonate, magnesium fluoride, magnesium silicate, barium sulphate, barium phosphate, barium carbonate, barium fluoride, barium silicate, or mixtures thereof. In a specific embodiment, the biodegradable hydrating ceramic is non-hydrated or hydrated calcium sulphate.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 20, 2008
    Applicant: Lidds Ab
    Inventors: Hans Lennernas, Bo Lennernas, Jonas Hugosson, Niklas Axen
  • Publication number: 20080187586
    Abstract: The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to deliver one or more glucocorticoids to a subject in need thereof in a manner that results in serum levels of the glucocorticoid that essentially mimic that of a healthy subject for a clinically relevant period of time. The pharmaceutical composition comprises one or more glucocorticoids, wherein a first part of one or more glucocorticoids is substantially immediately released and a second part of one or more glucocorticoids is released over an extended period of time of at least about 8 hours, and the amount of the one or more glucocorticoids of the first part, expressed as hydrocortisone equivalents, is in a range of from about 15 to about 50% of the total hydrocortisone equivalents.
    Type: Application
    Filed: April 21, 2005
    Publication date: August 7, 2008
    Applicant: DUOCORT AB
    Inventors: Stanko Skrtic, Jorgen Johnsson, Hans Lennernas, Thomas Hedner, Gudmundur Johannsson
  • Patent number: 6759059
    Abstract: A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which are adhered to the surface of carrier particles which are substantially larger than the particles of fentanyl, and are essentially water-soluble. In a preferred embodiment, the composition also contains a bioadhesion and/or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and to the use of the composition for the treatment of acute pain.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: July 6, 2004
    Assignee: Diabact AB
    Inventors: Anders Pettersson, Christer Nystrom, Hans Lennernas, Bo Lennernas, Thomas Hedner