Patents by Inventor Hans-Ludwig Schäfer

Hans-Ludwig Schäfer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cycloalkyl-substituted amino acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20050215596
    Abstract: Provided herein are cycloalkyl-substituted amino acid derivatives, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: September 29, 2005
    Applicant: Aventis Pharma Deutschland GMBH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Method of treatment with combinations of statin and aryl-substituted propanolamine derivatives
    Patent number: 6897198
    Abstract: Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which the radicals have the abovementioned meanings, and their physiologically tolerated salts, physiologically functional derivates and processes for their preparation. The compounds are suitable as, for example, hypolipidemics.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: May 24, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Reinhard Kirsch, Heiner Glombik, Werner Kramer, Hans-Ludwig Schäfer
  • Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20050101637
    Abstract: Provided herein are novel compounds of formula I below: in which the radicals are as defined, their physiologically acceptable salts, processes for their preparation, as well as methods of treating and/or preventing disorders of disorders of fatty acid metabolism and glucose utilization disorders, and also of disorders in which insulin resistance is involved, in a patient.
    Type: Application
    Filed: February 27, 2004
    Publication date: May 12, 2005
    Applicant: Aventis Pharma Deutschland GMBH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
    Patent number: 6884812
    Abstract: Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed. The compounds include those of formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds typically have lipid- and/or triglyceride-lowering properties and are suitable, for example, for the treatment of disorders of lipid metabolism, of type II diabetes, and of syndrome X.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: April 26, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Eugen Falk, Wendelin Frick, Stefanie Keil, Hans-Ludwig Schäfer, Lothar Schwink, Wolfgang Wendler
  • Nover diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use
    Publication number: 20050020563
    Abstract: The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 27, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Wendelin Frick, Andreas Lindenschmidt, Stefanie Flohr, Hubert Heuer, Hans-Ludwig Schaefer, Werner Kramer, Eric Galia, Heiner Glombik
  • Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040220261
    Abstract: The invention relates to arylcycloalkyl-substituted derivatives and to their physiologically acceptable salts and physiologically functional derivatives.
    Type: Application
    Filed: February 27, 2004
    Publication date: November 4, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Heiner Glombik, Eugen Falk, Dirk Gretzke, Jochen Goerlitzer, Stefanie Keil, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209920
    Abstract: Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • 1,3-substitued cycloalkyl derivatives having acidic, mostly heterocyclic groups; processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209932
    Abstract: The invention relates to 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups and to their physiologically acceptable salts and physiologically functional derivatives.
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Goerlitzer, Heiner Glombik, Eugen Falk, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209873
    Abstract: Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
    Publication number: 20040204462
    Abstract: Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 14, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Goerlitzer, Heiner Glombik, Eugen Falk, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040198786
    Abstract: Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Dirk Gretzke, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Application of intestinal biliary acid reuptake inhibitors for the prevention and treatment of alzheimer's disease
    Publication number: 20040138145
    Abstract: The subject of the invention is the application of intestinal biliary acid reuptake inhibitors for the prevention and treatment of Alzheimer's disease, where appropriate, in combination with an HMG-CoA reductase inhibitor, a cholesterol uptake inhibitor, a cholesterol synthesis inhibitor or an APP secretase inhibitor.
    Type: Application
    Filed: December 12, 2003
    Publication date: July 15, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Thierry Canton, Laurent Pradier, Jesus Benavides, Hubert Heuer, Hans-Ludwig Schaefer
  • Combination product of a 1,4-benzothiepine 1,1-dioxide compound with at least one other active ingredient and the use of the product
    Publication number: 20040097424
    Abstract: The present invention is directed to a 1,4-benzothiepine 1,1-dioxide compound of formula I 1
    Type: Application
    Filed: November 3, 2003
    Publication date: May 20, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Heiner Glombik, Wendelin Frick, Hans-Ludwig Schaefer, Werner Kramer
  • Ring -substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040082561
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 29, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040077623
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 22, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040067913
    Abstract: One embodiment of the invention relates to compounds of the formula I: 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 8, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Patent number: 6703386
    Abstract: Compounds of the formula I, for example, are disclosed, in which R1, R2, R3, R4, R5, and R6 independently of one another are (C0-C30)-alkylene-L or are the meanings given in the description, and where L is shown connected to (C0-C30)-alkylene as follows: where Rx, Ry, Rz have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: March 9, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schaefer
  • Use of bissulfonamides for producing medicines for the treatment of hyperlipidemia
    Patent number: 6632838
    Abstract: The use of bissulfonamides for producing medicines for the treatment of hyperlipidemia. The invention relates to the use of bissulfonamides and their salts for producing medicines for the treatment of hyperlipidemia. The use of compounds of formula I in which the radicals have the stated meanings, and of their salts for producing a medicine for the treatment of hyperlipidemia is described.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: October 14, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Reinhard Kirsch, Hans-Ludwig Schaefer, Eugen Falk, Norbert Krass
  • Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
    Patent number: 6624185
    Abstract: Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed. The compounds include those of formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds typically have lipid- and/or triglyceride-lowering properties and are suitable, for example, for the treatment of disorders of lipid metabolism, of type II diabetes, and of syndrome X.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: September 23, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Eugen Falk, Wendelin Frick, Stefanie Keil, Hans-Ludwig Schäfer, Lothar Schwink, Wolfgang Wendler
  • Combinations with statin and aryl-substituted propanolamine derivatives, their preparation pharmaceuticals comprising them, and their use
    Patent number: 6569835
    Abstract: Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which the radicals have the abovementioned meanings, and their physiologically tolerated salts, physiologically functional derivates and processes for their preparation. The compounds are suitable as, for example, hypolipidemics.
    Type: Grant
    Filed: November 1, 2001
    Date of Patent: May 27, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Reinhard Kirsch, Heiner Glombik, Werner Kramer, Hans-Ludwig Schäfer