Patents by Inventor Hans Michael Bürger

Hans Michael Bürger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-phenyl-2-pyrimidine-amine derivatives
    Patent number: 9573928
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: February 21, 2017
    Assignee: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • N-Phenyl-2-pyrimidine-amine Derivatives
    Publication number: 20150018552
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Application
    Filed: September 30, 2014
    Publication date: January 15, 2015
    Applicant: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • Salt forms of 4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide
    Publication number: 20140051853
    Abstract: The present invention relates to acid addition salts of 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide, which are selected from the group consisting of a tartrate salt, such as a (D)(?) tartrate salt or a (L)(+) tartrate salt, a hydrochloride salt, a citrate salt, a malate salt, a fumarate salt, a succinate salt, a benzoate salt, a benzenesulfonate salt, a pamoate salt, a formate salt, a malonate salt, a 1,5-naphthalenedisulfonate salt, a salicylate salt, a cyclohexanesulfamate salt, a lactate salt, a mandelate salt, aq glutarate salt, an adipate salt, a squarate salt, a vanillate salt, an oxaloacetate salt, an ascorbate salt and a sulfate salt.
    Type: Application
    Filed: July 19, 2013
    Publication date: February 20, 2014
    Applicant: Novartis AG
    Inventors: Hans Michael Bürger, Paul William Manley, Michael Mutz
  • Salt forms of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide
    Patent number: 8513256
    Abstract: The present invention relates to acid addition salts of 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide, which are selected from the group consisting of a tartrate salt, such as a (D)(?) tartrate salt or a (L)(+) tartrate salt, a hydrochloride salt, a citrate salt, a malate salt, a fumarate salt, a succinate salt, a benzoate salt, a benzenesulfonate salt, a pamoate salt, a formate salt, a malonate salt, a 1,5-naphthalenedisulfonate salt, a salicylate salt, a cyclohexanesulfamate salt, a lactate salt, a mandelate salt, aq glutarate salt, an adipate salt, a squarate salt, a vanillate salt, an oxaloacetate salt, an ascorbate salt and a sulfate salt.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: August 20, 2013
    Assignee: Novartis AG
    Inventors: Hans Michael Bürger, Paul William Manley, Michael Mutz
  • N-Phenyl-2-pyrimidine-amine Derivatives
    Publication number: 20120226039
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 6, 2012
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • Salt forms of 4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino)phenyl]-benzamide
    Publication number: 20120142697
    Abstract: The present invention relates to acid addition salts of 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide, which are selected from the group consisting of a tartrate salt, such as a (D)(?) tartrate salt or a (L)(+) tartrate salt, a hydrochloride salt, a citrate salt, a malate salt, a fumarate salt, a succinate salt, a benzoate salt, a benzenesulfonate salt, a pamoate salt, a formate salt, a malonate salt, a 1,5-naphthalenedisulfonate salt, a salicylate salt, a cyclohexanesulfamate salt, a lactate salt, a mandelate salt, aq glutarate salt, an adipate salt, a squarate salt, a vanillate salt, an oxaloacetate salt, an ascorbate salt and a sulfate salt.
    Type: Application
    Filed: February 8, 2012
    Publication date: June 7, 2012
    Inventors: Hans Michael Bürger, Paul William Manley, Michael Mutz
  • N-phenyl-2-pyrimidine-amine derivatives
    Patent number: 7825247
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: November 2, 2010
    Assignee: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • N-phenyl-2-pyrimidine-amine derivatives
    Patent number: 7816359
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: October 19, 2010
    Assignee: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • -phenyl-2-pyrimidine-amine derivatives
    Patent number: 7579467
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: August 25, 2009
    Assignee: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • N-phenyl-2-pyrimidine-amine derivatives
    Patent number: 7456283
    Abstract: The present invention relates to novel amides and a process for preparing these amides.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: November 25, 2008
    Assignee: Novartis AG
    Inventors: Olivier Loiseleur, Daniel Kaufmann, Stephan Abel, Hans Michael Bürger, Mark Meisenbach, Beat Schmitz, Gottfried Sedelmeier
  • N-phenyl-3-pyrimidine-amine derivatives
    Patent number: 7329661
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula I wherein the substituents are defined as indicated in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Grant
    Filed: July 26, 2007
    Date of Patent: February 12, 2008
    Assignee: Novartis AG
    Inventors: Hans Michael Buerger, Giorgio Caravatti, Juerg Zimmerman, Paul William Manley, Werner Breitenstein, Margaret Amelia Cudd
  • Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
    Patent number: 6894051
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]benzamide of formula 1, which may be used for example for tumor therapy.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: May 17, 2005
    Assignee: Novartis AG
    Inventors: Jürg Zimmermann, Bertrand Sutter, Hans Michael Bürger
  • N-phenyl-2-pyrimidine-amine derivatives
    Publication number: 20040102453
    Abstract: The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula (I) wherein the substituents are defined as indicated in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.
    Type: Application
    Filed: March 10, 2003
    Publication date: May 27, 2004
    Inventors: Hans Michael Buerger, Giorgio Caravatti, Juerg Zimmerman, Paul William Manley, Werner Breitenstein, Margaret Amelia Cudd
  • Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
    Patent number: RE43932
    Abstract: The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-yl-methyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of formula I, which may be used for example for tumour therapy.
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: January 15, 2013
    Assignee: Novartis AG
    Inventors: Juerg Zimmermann, Bertrand Sutter, Hans Michael Buerger