Abstract: A mobile disinfection apparatus for hospital waste has a worm conveyor leading from the bottom of the charging shaft at the back of a trailer bed to the mouth of a rotary tube reactor or rotary kiln enclosed in a heated hood which can be subdivided into separately heated zones. The reactor is formed with scoops which lift the waste comminuted in the charging shaft and cause it to cascade to contact the sterilizing medium and the sterilized waste passes into a discharge housing in which the waste is separated from the sterilizing medium which is recycled. The waste can be discharged and compacted by a worm conveyor which can be swung laterally outwardly from its transport position to discharge the waste for further handling like household or municipal waste.