Patents by Inventor Hans O. Kalkman

Hans O. Kalkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 1H-Quinazoline-2,4-Diones
    Publication number: 20140018376
    Abstract: The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of Rasmussen's encephalitis and/or certain forms of epilepsy.
    Type: Application
    Filed: October 20, 2010
    Publication date: January 16, 2014
    Inventors: Hans Allgeier, Yves Auberson, Thomas Blaettler, David Carcache, Philipp Floersheim, Wolfgang Froestl, Christel Guibourdenche, Hans o Kalkman, Joerg Kallen, Manuel Koller, Kurt Lingenhohl, Henri Mattes, Joachim Nozulak, David Orain, Johanne Renaud, Christine Strohmaier
  • OPTICAL ISOMERS OF AN ILOPERIDONE METABOLITE
    Publication number: 20130296366
    Abstract: The present invention relates to novel isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: October 26, 2012
    Publication date: November 7, 2013
    Inventors: Dominique Grimler, Hans O. Kalkman, Hequn Yin
  • Use of 1H-quinazoline-2,4-diones
    Publication number: 20130096145
    Abstract: The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of spasticity.
    Type: Application
    Filed: June 24, 2011
    Publication date: April 18, 2013
    Applicant: Novartis AG
    Inventor: Hans O. Kalkman
  • Optical isomers of an iloperidone metabolite
    Patent number: 8314129
    Abstract: The present invention relates to novel isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: November 20, 2012
    Assignee: Novartis AG
    Inventors: Dominique Grimler, Hans O. Kalkman, Hequn Yin
  • 1-H-QUINAZOLINE-2, 4-DIONES FOR USE IN THE TREATMENT OF NEURONAL CEROID LIPOFUSCINOSIS
    Publication number: 20120122903
    Abstract: The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of neuronal ceroid lipofuscinosis.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 17, 2012
    Inventors: Hans O Kalkman, Henri Mattes
  • COMBINATIONS FOR THE TREATMENT OF MIGRAINE
    Publication number: 20110212980
    Abstract: The present invention relates to novel combinations suitable for the treatment of migraine of various genesis or aetiology, which comprise, as active ingredients, at least one 5-HT1 B/1 D receptor agonist and at least one selective, competitive AMPA receptor antagonist being a 1 H-quinazoline-2,4-dione of formula (I) as defined in the claims; to their preparation; to their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: October 21, 2009
    Publication date: September 1, 2011
    Inventors: Graeme Bilbe, Baltazar Gomez-Mancilla, Daniel Hoyer, Donald Johns, Hans O. Kalkman, Kevin Hall Mcallister
  • OPTICAL ISOMERS OF AN ILOPERIDONE METABOLITE
    Publication number: 20110201646
    Abstract: The present invention relates to novel isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: April 28, 2011
    Publication date: August 18, 2011
    Inventors: Dominique Grimler, Hans O. Kalkman, Hequn Yin
  • BENZISOXAZOLES
    Publication number: 20110172272
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: March 14, 2011
    Publication date: July 14, 2011
    Inventors: Joachim Nozulak, Hans O. Kalkman
  • Optical isomers of an Iloperidone metabolite
    Patent number: 7977356
    Abstract: The present invention relates to novel isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: July 12, 2011
    Assignee: Novartis AG
    Inventors: Dominique Grimler, Hans O. Kalkman, Hequn Yin
  • COMBINATIONS OF NICOTINIC ACETYLCHOLINE ALPHA 7 RECEPTOR AGONISTS
    Publication number: 20100125063
    Abstract: Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders.
    Type: Application
    Filed: January 20, 2010
    Publication date: May 20, 2010
    Inventors: Hans O. KALKMAN, Joachim NOZULAK, Annick VASSOUT, Konstanze HURTH, Dominik FEUERBACH, Conrad GENTSCH, Graeme BILBE
  • OPTICAL ISOMERS OF AN ILOPERIDONE METABOLITE
    Publication number: 20090176739
    Abstract: The present invention relates to novel isomers of a metabolite of Iloperidone, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: March 13, 2009
    Publication date: July 9, 2009
    Inventors: Dominique Grimler, Hans O. Kalkman, Hequn Yin
  • NEW USE OF ILOPERIDONE
    Publication number: 20090131477
    Abstract: The invention relates to the use of iloperidone in the treatment of affective disorders, including bipolar mood disorders.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 21, 2009
    Inventor: Hans O. Kalkman
  • Combinations of Nicotinic Acetylcholine Alpha 7 Receptor Antagonists
    Publication number: 20080306081
    Abstract: Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders.
    Type: Application
    Filed: November 3, 2005
    Publication date: December 11, 2008
    Applicant: NOVARTIS AG
    Inventors: Hans O. Kalkman, Joachim Nozulak, Annick Vassout, Konstanze Hurth, Dominik Feuerbach, Conrad Gentsch, Graeme Bilbe
  • Use of iloperidone
    Publication number: 20040072869
    Abstract: The invention relates to the use of iloperidone in the treatment of affective disorders, including bipolar mood disorders.
    Type: Application
    Filed: July 29, 2003
    Publication date: April 15, 2004
    Inventor: Hans O. Kalkman