Patents by Inventor HANS P. I. CLAESSON

HANS P. I. CLAESSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR USE OF A DOUBLE-STRUCTURED TISSUE IMPLANT FOR TREATMENT OF TISSUE DEFECTS
    Publication number: 20230277291
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Application
    Filed: May 15, 2023
    Publication date: September 7, 2023
    Applicant: Ocugen, Inc.
    Inventors: Sonya Shortkroff, Laurence J.B. Tarrant, Eric J. Roos, Hans P.I. Claesson
  • Method for use of a double-structured tissue implant for treatment of tissue
    Patent number: 11648102
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: May 16, 2023
    Assignee: Ocugen, Inc.
    Inventors: Sonya Shortkroff, Laurence J. B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P. I. Claesson
  • CELL-SUPPORT MATRIX HAVING NARROWLY DEFINED UNIFORMLY VERTICALLY AND NON-RANDOMLY ORGANIZED POROSITY AND PORE DENSITY AND A METHOD FOR PREPARATION THEREOF
    Publication number: 20210246418
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 12, 2021
    Applicant: Histogenics Corporation
    Inventors: Robert Lane Smith, Laurence J.B. Tarrant, Akihiko Kusanagi, Hans P.I. Claesson
  • METHOD FOR USE OF A DOUBLE-STRUCTURED TISSUE IMPLANT FOR TREATMENT OF TISSUE DEFECTS
    Publication number: 20210059805
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Application
    Filed: November 16, 2020
    Publication date: March 4, 2021
    Applicant: HISTOGENICS CORPORATION
    Inventors: Sonya Shortkroff, Laurence J.B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P.I. Claesson
  • Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
    Patent number: 10900017
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: January 26, 2021
    Assignee: HISTOGENICS CORPORATION
    Inventors: Robert Lane Smith, Laurence J. B. Tarrant, Akihiko Kusanagi, Hans P. I. Claesson
  • Method for use of a double-structured tissue implant for treatment of tissue defects
    Patent number: 10842610
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: November 24, 2020
    Assignee: Histogenics Corporation
    Inventors: Sonya Shortkroff, Laurence J. B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P. I. Claesson
  • CELL-SUPPORT MATRIX HAVING NARROWLY DEFINED UNIFORMLY VERTICALLY AND NON-RANDOMLY ORGANIZED POROSITY AND PORE DENSITY AND A METHOD FOR PREPARATION THEREOF
    Publication number: 20200224155
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Application
    Filed: December 6, 2019
    Publication date: July 16, 2020
    Applicant: HISTOGENICS CORPORATION
    Inventors: Robert Lane Smith, Laurence J.B. Tarrant, Akihiko Kusanagi, Hans P.I. Claesson
  • COLLAGEN BASED MATERIALS AND METHODS OF USING THEM
    Publication number: 20190001020
    Abstract: Certain configurations of adhesive materials are described which comprise a crosslinked derivatized atelocollagen. In some configurations, the crosslinked, derivatized atelocollagen is cured to provide a burst strength of at least 55 kPa or 60 kPa (or more) as tested by ASTM F2392-04. In some instances, the crosslinked derivatized atelocollagen comprises a methylated atelocollagen that is crosslinked using one or more functionalized crosslinking agents.
    Type: Application
    Filed: January 22, 2018
    Publication date: January 3, 2019
    Inventors: Hans P.I. Claesson, Laurence J. Berlowitz, Matthew Fullana, Gary E. Wnek
  • METHOD FOR USE OF A DOUBLE-STRUCTURED TISSUE IMPLANT FOR TREATMENT OF TISSUE DEFECTS
    Publication number: 20180256309
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Applicant: Histogenics Corporation
    Inventors: Sonya Shortkroff, Laurence J.B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P.I. Claesson
  • Method for use of a double-structured tissue implant for treatment of tissue defects
    Patent number: 9993326
    Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand alone secondary scaffold implant or unit for treatment of tissue defects.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: June 12, 2018
    Assignee: Histogenics Corporation
    Inventors: Sonya Shortkroff, Laurence J. B. Tarrant, Eric J. Roos, Robert Lane Smith, Hans P. I. Claesson
  • Cohesive materials including derivatized collagens and methods of making and using them
    Patent number: 9919075
    Abstract: Certain embodiments described herein are directed to cohesive materials comprising treated, derivatized collagen molecules. In some embodiments, the cohesive material can function as a putty or defect filler that can be used in a tissue repair. Methods of using the cohesive materials are also described.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: March 20, 2018
    Assignee: Anexis, LLC
    Inventors: Laurence J Berlowitz, Hans P. I. Claesson, Matthew Fullana, Gary E Wnek
  • ADHESIVE MATERIALS AND SEQUESTERED CURING AGENTS USED TO PRODUCE THEM
    Publication number: 20180021237
    Abstract: Certain configurations of adhesive materials are described which comprise a crosslinked derivatized atelocollagen that can be cured with a sequestered curing agent. In some configurations, the crosslinked, derivatized atelocollagen is used to provide an adhesive that can be used to hold two or more tissues to each other for some period and permit a tissue repair process to occur.
    Type: Application
    Filed: July 16, 2017
    Publication date: January 25, 2018
    Inventors: Hans P.I. Claesson, Laurence J Berlowitz, Matthew Fullana, Gary E Wnek
  • CELL-SUPPORT MATRIX HAVING NARROWLY DEFINED UNIFORMLY VERTICALLY AND NON-RANDOMLY ORGANIZED POROSITY AND PORE DENSITY AND A METHOD FOR PREPARATION THEREOF
    Publication number: 20170298320
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Application
    Filed: July 5, 2017
    Publication date: October 19, 2017
    Inventors: Robert Lane Smith, Laurence J.B. Tarrant, Akihiko Kusanagi, Hans P.I. Claesson
  • Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
    Patent number: 9701940
    Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: July 11, 2017
    Assignee: Histogenics Corporation
    Inventors: R. Lane Smith, Laurence J. B. Tarrant, Akihiko Kusanagi, Hans P. I. Claesson
  • COLLAGEN BASED MATERIALS AND METHODS OF USING THEM
    Publication number: 20170087272
    Abstract: Certain configurations of adhesive materials are described which comprise a crosslinked derivatized atelocollagen. In some configurations, the crosslinked, derivatized atelocollagen is cured to provide a burst strength of at least 55 kPa or 60 kPa (or more) as tested by ASTM F2392-04. In some instances, the crosslinked derivatized atelocollagen comprises a methylated atelocollagen that is crosslinked using one or more functionalized crosslinking agents.
    Type: Application
    Filed: July 20, 2016
    Publication date: March 30, 2017
    Inventors: Hans P.I. Claesson, Laurence J Berlowitz, Matthew Fullana, Gary E Wnek
  • METHOD FOR IMPROVEMENT OF DIFFERENTIATION OF MESENCHYMAL STEM CELLS USING A DOUBLE-STRUCTURED TISSUE IMPLANT
    Publication number: 20160331507
    Abstract: A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
    Type: Application
    Filed: July 28, 2016
    Publication date: November 17, 2016
    Inventors: Sonya Shortkroff, Joseph Khoury, Laurence J.B. Tarrant, Hans P.I. Claesson, Robert Lane Smith
  • Method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant
    Patent number: 9421304
    Abstract: A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: August 23, 2016
    Assignee: Histogenics Corporation
    Inventors: Sonya Shortkroff, Joseph Khoury, Laurence J. B. Tarrant, Hans P. I. Claesson, Robert Lane Smith
  • COHESIVE MATERIALS INCLUDING DERIVATIZED COLLAGENS AND METHODS OF MAKING AND USING THEM
    Publication number: 20160213814
    Abstract: Certain embodiments described herein are directed to cohesive materials comprising treated, derivatized collagen molecules. In some embodiments, the cohesive material can function as a putty or defect filler that can be used in a tissue repair. Methods of using the cohesive materials are also described.
    Type: Application
    Filed: March 19, 2015
    Publication date: July 28, 2016
    Inventors: Laurence J. Berlowitz, Hans P.I. Claesson, Matthew Fullana, Gary E. Wnek
  • Method For Improvement Of Differentiation Of Mesenchymal Stem Cells Using A Double-Structured Tissue Implant
    Publication number: 20160206787
    Abstract: A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
    Type: Application
    Filed: August 20, 2008
    Publication date: July 21, 2016
    Applicant: HISTOGENICS CORPORATION
    Inventors: Sonya Shortkroff, Joseph Khoury, Laurence J.B. Tarrant, Hans P.I. Claesson, Robert Lane Smith
  • Double-structured tissue implant and a method for preparation and use thereof
    Patent number: 9393347
    Abstract: A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold comprised of collagen and a secondary scaffold comprising a soluble collagen solution in combination with a surfactant generated and positioned within the primary scaffold. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: July 19, 2016
    Assignee: Histogenics Corporation
    Inventors: Hans P. i. Claesson, Laurence J. B. Tarrant, R. Lane Smith, Sonya Shortkroff