Patents by Inventor Hans P. Schwarz

Hans P. Schwarz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioassay for thrombogenesis and rabbit model
    Patent number: 5675058
    Abstract: An in vivo assay for determining the potential thrombogenic activity of a test compound entails pre-treating an animal with both a hepatoxin and either a bacterial agent (whole bacteria or bacterial toxins, including endotoxins) or a bacterial agent-induced cytokine, which pre-treatment enhances sensitivity to thrombogenic substances. The sensitized animal can be used in identifying a thrombogenic substance even when it is a weak potentiator of thrombogenesis, and in detecting smaller amounts of a strong potentiator.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: October 7, 1997
    Assignee: Immuno AG
    Inventors: Johann J. Eibl, Hans P. Schwarz, Ludwig Pichler
  • Parenterally administrable drug having thrombolytic activity and containing protein C
    Patent number: 5580962
    Abstract: A thrombolytic, parenterally administrable drug containing activated protein C is provided for. The drug is free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and activated protein C.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: December 3, 1996
    Assignee: Immuno Aktiengesellschaft
    Inventors: Johann Eibl, Yendra Linnau, Anton Philapitsch, Hans P. Schwarz
  • Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
    Patent number: 5571786
    Abstract: There is disclosed the use of protein C and/or the activation peptide of protein C for preparing a pharmaceutical preparation having anti-nociceptive activity. This pharmaceutical preparation is useful in the treatment of painful conditions caused by acute or chronic inflammatory processes (such as rheumatoid arthritis, myositis, gastritis, colitis, inflammations in the urogenital tract).
    Type: Grant
    Filed: January 20, 1995
    Date of Patent: November 5, 1996
    Assignee: Immuno Aktiengesellschaft
    Inventors: Johann Eibl, Ludwig Pichler, Hans P. Schwarz, Peter Turecek
  • Use of protein C in the treatment of purpura fulminans
    Patent number: 5549893
    Abstract: There is disclosed the use of protein C or activated protein C for preparing a drug useful for the maintenance and improvement of the microcirculation in patients suffering from circulatory disturbances, in particular with the proviso that the drug does not contain any immunoglobulin G.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: August 27, 1996
    Assignee: Immuno Aktiengesellschaft
    Inventors: Johann Eibl, Ludwig Pichler, Hans P. Schwarz
  • Method of dissolving venous Thrombi using drug containing activated Protein C
    Patent number: 5478558
    Abstract: A method of dissolving venous thrombi using a thrombolytic, parenterally administrable drug containing activated protein C is described. The drug can be free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and activated protein C.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: December 26, 1995
    Assignee: Immuno AG
    Inventors: Johann Eibl, Yendra Linnau, Anton Philapitsch, Hans P. Schwarz
  • Method of preparing activated protein C
    Patent number: 5330907
    Abstract: To produce activated protein C, protein C is treated with plasmin. Activation is effected in a quick and simple manner. Contamination of the activated protein C with thrombin is avoided.
    Type: Grant
    Filed: June 17, 1992
    Date of Patent: July 19, 1994
    Assignee: Immuno Aktiengesellschaft
    Inventors: Anton Philapitsch, Hans P. Schwarz
  • Pharmaceutical preparation based on Lys-plasminogen
    Patent number: 5304383
    Abstract: There is disclosed a pharmaceutical preparation based on Lys-plasminogen and available in the lyophilized form. This preparation contains a serine-protease inhibitor and optionally an inhibitor co-factor, preferably in an amount of 0.5 to 30 nmol per mg Lys-plasminogen. This preparation is free of side-effects and may be used for the treatment and prophylaxis of plasminogen deficiency syndromes and thromboses as well as for the production of thromboresistant artificial organs.
    Type: Grant
    Filed: October 8, 1991
    Date of Patent: April 19, 1994
    Assignee: Immuno Aktiengesellschaft
    Inventors: Johann Eibl, Anton Philapitsch, Hans P. Schwarz
  • Preparation for treating and preventing thromboses and thromboembolic complications, use of such a preparation and a method of producing the same
    Patent number: 5254532
    Abstract: A preparation for the treatment and prevention of thromboses and thromboembolic complications is disclosed, which preparation has a content of protein S at a concentration at least 50 times that present in native plasma and is free from C4b-binding protein, optionally in combination with a content of activated protein C.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: October 19, 1993
    Assignee: Immuno Aktiengesellschaft fur chemisch-medizinische Produkte
    Inventors: Hans P. Schwarz, Ewald Molinari, Yendra Linnau, Susanne Pfeiler
  • Preparation for treating and preventing thromboses and thromboembolic complications, use of such a preparation and a method of producing the same
    Patent number: 5143901
    Abstract: A preparation for the treatment and prevention of thromboses and thromboembolic complications is disclosed, which preparation has a content of protein S at a concentration at least 50 times that present in native plasma and is free from C4b-binding protein, optionally in combination with a content of activated protein C.
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: September 1, 1992
    Assignee: Immuno Aktiengesellschaft
    Inventors: Hans P. Schwarz, Ewald Molinari, Yendra Linnau, Susanne Pfeiler