Abstract: The invention relates to a multilayer adhesive strip comprising a carrier layer and at least one adhesive layer arranged on the carrier layer, wherein the carrier layer comprises a syntactically foamed plastic; the adhesive layer comprises a syntactically foamed adhesive compound; the adhesive compound comprises one or more polymers selected from the group consisting of poly(meth)acrylates and synthetic rubbers; and the syntactically foamed plastic and the syntactically foamed adhesive compounds comprise a plurality of expanded microballoons.

Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: The present invention relates to a method of immobilizing a cell on a support, the method comprising a) providing a compound or salt thereof comprising, preferably consisting of, one or more hydrophobic domains attached to a hydrophilic domain, wherein the one or more hydrophobic domains are covalently bound to said hydrophilic domain, and wherein the one or more hydrophobic domains each comprise a linear lipid, a steroid or a hydrophobic vitamin, and wherein the hydrophilic domain comprises a polyethylene glycol (PEG) moiety, and wherein the compound comprises a linking group; b) contacting a cell with the compound under conditions allowing the interaction of the compound with the membrane of the cell, thereby immobilizing the linking group on the surface of the cell; and c) contacting the linking group immobilized on the cell with a support capable of binding the linking group, thereby immobilizing the cell on the support.

Abstract: The present disclosure provides improved compositions for the homology directed repair of the human globin locus for the prevention, treatment, or amelioration of at least one symptom of a hemoglobinopathy.

Abstract: The invention relates to an adhesive tape for jacketing elongated items such as more particularly leads or cable sets, comprising a tapelike carrier provided on at least one side with a curable adhesive, characterized in that the adhesive tape is further provided on one side of the tapelike carrier with a release layer of carbamate.

Abstract: A method for generating a copy of a database using a data streaming protocol is disclosed. The method comprises setting up a structure of a secondary database, prioritizing data objects to be copied from a primary database to the secondary database, copying data objects from the primary database to the secondary database using a data streaming protocol, restoring data corresponding to the data object in the secondary database in parallel to copying data objects from the primary database to the secondary database, applying changes made to the data corresponding to the data object in the primary database during the time of copying, after the data object has been copied, and making available the secondary database for usage once all data objects have been copied from the primary database to the secondary database so that a usable copy of the primary database is created.

Abstract: The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and\or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content.

Abstract: Exemplary embodiments are directed to wireless charging and wireless power alignment of wireless power antennas associated with a vehicle. A wireless power charging apparatus includes an antenna including first and second orthogonal magnetic elements for detecting a horizontal component of a magnetic field generated from a second charging base antenna. A processor determines a directional vector between the antennas.

Abstract: Two-component paint system comprising a binding agent component and a curing agent component which are separated from one another prior to application of the paint system and are brought into contact with one another for application, so that the binding agent in the binder component crosslinks by contact with the curing agent component, with the binder component containing, in addition to the binding agent, at least one solvent which is unreactive with the curing agent component, a crosslinking catalyst and a propellant agent, characterized in that the curing agent component is obtainable by pre-reaction of a deficient amount of a bi- or trifunctional low-molecular-weight active hydrogen-carrying compound with an isocyanate-based crosslinker having a residual content of monomeric or dimeric isocyanates of ?1% w/w, said paint system being contained in a 2K aerosol spray can provided with an inner casing.

Abstract: In certain aspects, an enclosure for a wireless power transfer pad is disclosed. The enclosure includes a cover shell configured to be positioned over a portion of the wireless power transfer pad configured to face a wireless power receiver when wirelessly transferring power, wherein at least a portion of the cover shell is made of a heat resistant material.

Abstract: A method for determining a temperature compensation parameter for compensation of temperature effects on measured values of a sensor system having a sensor unit for acquiring measured values of a sensor measuring variable.

Abstract: The present invention relates to a method for producing a protein hydrolysate using a polypeptide having endopeptidase activity and a polypeptide having carboxypeptidase activity and the use of these enzymes for hydrolysing a protein substrate. In addition, the present invention relates to polypeptides having carboxypeptidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

Abstract: A means of transport, in particular a pedelec, which can be driven by means of drive energy produced electromotively and by human muscular power, comprising a drive unit in which an electric drive motor and a harmonic drive transmission are nested one inside the other, thereby saving space.

Abstract: A field effect transistor (FET) is proposed. The FET includes a transistor cell area in a silicon carbide (SiC) semiconductor body. An edge termination area surrounds the transistor cell area. A source contact is arranged over a first surface of the SiC semiconductor body. A drain contact is arranged on a second surface of the SiC semiconductor body. The FET further includes a drift region of a first conductivity type between the first surface and the second surface. Along a lateral direction, a net doping concentration in the drift region is larger in the transistor cell area than in the edge termination area.

Abstract: Embodiments relate to a test method for testing an unpopulated printed circuit board. The method can involve the steps of: exposing the unpopulated printed circuit board to temperatures of a reflow soldering process in a first step; and testing the electrical connections of the unpopulated printed circuit board. Embodiments also relate to a test device and a method for producing populated printed circuit boards.

Abstract: Exemplary embodiments are directed to wireless charging and wireless power alignment of wireless power antennas associated with a vehicle. A wireless power charging apparatus includes an antenna including first and second orthogonal magnetic elements for detecting a horizontal component of a magnetic field generated from a second charging base antenna. A processor determines a directional vector between the antennas.

Abstract: A valve for a packaging container is proposed, wherein the valve comprises at least one base film (10) with an opening (11), at least one frame film (13) encompassing a free region (17), and at least one membrane (12) which is arranged on the base film (10) and covers the opening (11), wherein a fluid is provided between the membrane (12) and the base film (10), wherein the membrane (12) is connected to a surrounding film (20) via at least one connection region (22), the surrounding film (20) being connected on one side to the base film (10) and on its other side to the frame film (13) and the membrane (12) being arranged movably within the free region (17), wherein the surrounding film (20) is open at least in one point, such that a channel (18) is formed.

Abstract: The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.

Abstract: Provided herein are compositions and methods for treating and/or ameliorating the FOXG1 syndromes or the symptoms associated therewith. The compositions and methods disclosed herein utilize antisense oligonucleotides that target long non-coding RNAs (lncRNAs) to increase FOXG1 expression in a cell, thereby restoring FOXG1 function.

Abstract: The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC.