Abstract: The invention relates to an active substance-containing plaster for the controlled administration of active substances to the skin, which has a back and a skin side, with a back layer, an active substance reservoir divided substantially perpendicularly to the skin contact surface of the plaster and having one or more active substances, a contact adhesive device on the skin side and optionally a cover layer detachable prior to the application of the plaster, whereas at least one active substance reservoir part (12) is detachable from the skin, while leaving behind one or more active substance reservoir parts (13) on the skin. For this object there is provided that the part of the active substance reservoir remaining on the skin is having a better adhesion to the skin than to the back layer (11).

Abstract: The present invention relates to a transdermal therapeutic system with tulobuterol or one of the pharmaceutically acceptable salts thereof as active substance, comprising a backing layer which is substantially impermeable to active substances and at least one matrix layer which contains the active substance, which matrix layer comprises at least one styrene-1,3-diene-styrene block copolymer. The present invention is further directed to a process for the production of said transdermal therapeutic system.

Abstract: A transdermal therapeutic system is disclosed which comprises an optional flexible backing layer, one or more drug reservoir(s), one or more adhesive layer(s) and optionally a detachable protective layer for the skin contact surface of the flat therapeutical system. The skin contact area of the therapeutical system is a skin contact layer which has one or more non-adhesive drug-releasing section(s) and one or more skin-adhesion section(s), which optionally contain a further drug. A process is disclosed for the production of the system, as well as the use thereof for local or systemic, transdermal administration of drugs in human or veterinary medicine or in cosmetics.

Abstract: The present invention is related to a pharmaceutical product preferably in medical bandage form, for the controlled release of a therapeutically active agent or several such agents to the skin.

Abstract: The present invention is related to a flat laminate part consisting of a substrate layer and a cover layer the adhesive compounding between said substrate layer and said cover layer being such that both layers are securely held together, but a pull-off of said cover layer from said substrate layer is readily possible by hand or mechanically, said flat laminate part having additionally an auxiliary pull-off means to so pull-off said cover layer or parts of said cover layer by hand or mechanically along preset cuts or, respectively, preset breaking lines in said cover layer, wherein said preset cuts or preset breaking lines in said cover layer are positioned and formed such that there is at least one part of the cover layer which can be grasped per each part of said cover layer to be pulled off, said grasp part is, getting exposed by bending the flat laminate part getting exposed by bending the flat laminate part to form a concave curvature of the surface of said cover layer opposite to the surface of said cove