Patents by Inventor Hans-Reinhard Zerkowski

Hans-Reinhard Zerkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240074859
    Abstract: An annuloplasty implant is disclosed comprising first and second support members having a coiled configuration in which the first and second support members are arranged as a coil, with two free ends, around a central axis, wherein, in said coiled configuration, said two free ends are displaced from each other with a peripheral off-set distance extending in a coil plane, said coil plane being substantially parallel to an annular periphery of said coil and perpendicular to said central axis, wherein the first and second support members and the respective free ends are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve. A method of implanting an annuloplasty implant at a target site in the heart is also disclosed.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 7, 2024
    Inventors: Hans-Reinhard ZERKOWSKI, Olli KERANEN, Ger O'CARROL, Mark PUGH, Jake O'REGAN, Stuart DEANE
  • Publication number: 20240041604
    Abstract: An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS, and wherein the distal anchoring portion comprises an inflatable unit.
    Type: Application
    Filed: August 18, 2023
    Publication date: February 8, 2024
    Inventors: Olli KERANEN, Hans-Reinhard ZERKOWSKI, Jouko VALLIKARI
  • Patent number: 11813163
    Abstract: A method for connecting an annuloplasty implant with a delivery and retrieval device includes retracting the annuloplasty implant towards a locking structure of the delivery and retrieval device with a retrieval element. The retrieval element connects the annuloplasty implant with the delivery and retrieval device when the annuloplasty implant is disconnected from the delivery and retrieval device. A complementary mating surface at an end portion of the annuloplasty implant is interlocked with a locking structure of the delivery and retrieval device. The complementary mating surface has a recess for locking longitudinal movement of the annuloplasty implant when it is received in the locking structure. The complementary mating surface has a first locking surface aligned in a first radial direction (R) to lock rotational movement of the annuloplasty implant, when received in the locking structure, around the longitudinal direction.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: November 14, 2023
    Assignee: HVR Canlio Oy
    Inventors: Hans-Reinhard Zerkowski, Ger O'Carroll, Mark Pugh
  • Patent number: 11793641
    Abstract: An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: October 24, 2023
    Inventors: Olli Keränen, Jouko Vallikari, Hans-Reinhard Zerkowski
  • Publication number: 20230310154
    Abstract: A method of repairing a defective heart valve is disclosed comprising directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.
    Type: Application
    Filed: June 12, 2023
    Publication date: October 5, 2023
    Inventors: Hans-Reinhard Zerkowski, Olli Keranen, Jani Virtanen
  • Patent number: 11730599
    Abstract: An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS, and wherein the distal anchoring portion comprises an inflatable unit.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: August 22, 2023
    Assignee: HVR Cardio Oy
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski, Jouko Vallikari
  • Patent number: 11696829
    Abstract: A method of repairing a defective heart valve is disclosed including directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: July 11, 2023
    Assignee: Medtentia International Ltd Oy
    Inventors: Hans-Reinhard Zerkowski, Olli Keränen, Jani Virtanen
  • Publication number: 20230157822
    Abstract: A method of repairing a defective heart valve involves positioning first and second support rings of an annuloplasty device in a first configuration on opposite sides of native heart valve leaflets and activating a contracted state of the annuloplasty device so that a first pitch distance between the first and second support rings in the first configuration is reduced to a second pitch distance that is shorter than the first pitch distance to move the first and second support rings toward each other to pinch the native heart valve leaflets.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: Olli KERANEN, Hans-Reinhard ZERKOWSKI, Johannes JUNG
  • Publication number: 20230105943
    Abstract: An annuloplasty device is disclosed comprising first and second support rings having a coiled configuration, and respective first and second retention units, the first support ring transitions to the second support ring over a transition section, the transition section is adapted to be arranged at a commissure of the heart valve leaflets, the first and second support rings extend in respective first and second coil planes being essentially perpendicular to the central axis, the transition section bends at least partly along the central axis so that the first coil plane is separated a distance from the second coil plane along the central axis at the transition section.
    Type: Application
    Filed: October 13, 2022
    Publication date: April 6, 2023
    Inventors: Olli Keranen, Hans-Reinhard Zerkowski, Johannes Jung, Jani Virtanen
  • Publication number: 20230086853
    Abstract: A method of making an annuloplasty implant includes forming first and second support rings arranged in a coiled configuration around an axial direction and forming at least part of the first and second support ring from a carbon fiber material. The first and second support rings can be formed by 3-D printing according to dimensions of a 3-D reconstruction of a heart valve.
    Type: Application
    Filed: November 27, 2022
    Publication date: March 23, 2023
    Inventors: Hans-Reinhard ZERKOWSKI, Olli KERANEN
  • Patent number: 11547563
    Abstract: An annuloplasty device is disclosed comprising first and second support rings being configured to be arranged as a coil in a first configuration around an axial direction, wherein the first and second support rings are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve, wherein the first and second support rings are separated with a first pitch distance in the axial direction, in the first configuration, wherein the first and second support rings are configured to assume a contracted state having a second pitch distance in the axial direction being shorter than the first pitch distance, and wherein the first and second support rings are configured to be transferable between the first configuration and the contracted state to pinch the heart valve leaflets. A method of repairing a defective heart valve is also disclosed.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: January 10, 2023
    Assignee: Medtentia International Ltd. Oy
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski, Johannes Jung
  • Patent number: 11510781
    Abstract: An annuloplasty implant is disclosed comprising first and second support rings arranged in a coiled configuration around an axial direction, and being adapted to be arranged on opposite sides of native heart valve leaflets to pinch said leaflets. At least part of said first and second support ring is formed from a carbon fiber material. The first and second support rings are resiliently movable with respect to each other in opposite directions along said axial direction. A method of manufacturing an annuloplasty implant is also disclosed.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: November 29, 2022
    Inventors: Hans-Reinhard Zerkowski, Olli Keränen
  • Patent number: 11491008
    Abstract: An annuloplasty device is disclosed comprising first and second support rings having a coiled configuration, and respective first and second retention units, the first support ring transitions to the second support ring over a transition section, the transition section is adapted to be arranged at a commissure of the heart valve leaflets, the first and second support rings extend in respective first and second coil planes being essentially perpendicular to the central axis, the transition section bends at least partly along the central axis so that the first coil plane is separated a distance from the second coil plane along the central axis at the transition section.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: November 8, 2022
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski, Johannes Jung, Jani Virtanen
  • Publication number: 20220346953
    Abstract: An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS.
    Type: Application
    Filed: March 30, 2020
    Publication date: November 3, 2022
    Inventors: Olli Keränen, Jouko Vallikari, Hans-Reinhard Zerkowski
  • Publication number: 20220323218
    Abstract: A method for connecting an annuloplasty implant with a delivery and retrieval device includes retracting the annuloplasty implant towards a locking structure of the delivery and retrieval device with a retrieval element. The retrieval element connects the annuloplasty implant with the delivery and retrieval device when the annuloplasty implant is disconnected from the delivery and retrieval device. A complementary mating surface at an end portion of the annuloplasty implant is interlocked with a locking structure of the delivery and retrieval device. The complementary mating surface has a recess for locking longitudinal movement of the annuloplasty implant when it is received in the locking structure. The complementary mating surface has a first locking surface aligned in a first radial direction (R) to lock rotational movement of the annuloplasty implant, when received in the locking structure, around the longitudinal direction.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 13, 2022
    Inventors: Hans-Reinhard Zerkowski, Ger O'Carroll, Mark Pugh
  • Publication number: 20220218480
    Abstract: An annuloplasty system is disclosed comprising an annuloplasty implant and a delivery device, the annuloplasty implant comprising first and second supports being adapted to be arranged on opposite sides of native heart valve leaflets. The delivery device comprising a locking structure to interlock with a correspondingly mating first locking structure of a delivery device connector of the annuloplasty implant, the locking structure comprising a first locking side to lock rotational movement of the annuloplasty implant, when interlocked with the delivery device, around an axial direction of the annuloplasty implant, and a second locking side to lock movement of the annuloplasty implant along said axial direction, when interlocked with the delivery device. A method of repairing a defective heart valve is also disclosed.
    Type: Application
    Filed: April 30, 2020
    Publication date: July 14, 2022
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski, Rainer Trapp, Jani Vertanen, Johannes Jung
  • Patent number: 11382748
    Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve. A first flange unit is may be configured as a fabric sleeve covering the loop-shaped support. A portion of the fabric sleeve forms a flange that is attached to the annulus when said first loop-shaped support is abutting said heart valve. The flange is provideable by folding at least a portion of said sleeve over itself for forming a double layer of opposing fabrics thereof, such that said sleeve comprises a flange portion extending from said first loop-shaped support configured to overlap a surface of and form a collar around, at least a portion of said annulus.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: July 12, 2022
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski
  • Publication number: 20220211499
    Abstract: A method for repairing a defective heart valve includes directing a delivery catheter to form a first curve around the heart valve at a first side of the heart valve leaflets and forming a second curve of the delivery catheter around the heart valve on a second side of the heart valve leaflets. The first and second curves are connected through a commissure of the heart valve and an annuloplasty implant is ejected from the delivery catheter while the delivery catheter is retracted such that the annuloplasty implant is arranged along the first and second curve.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 7, 2022
    Inventors: Hans-Reinhard ZERKOWSKI, Olli KERÄNEN
  • Publication number: 20220202570
    Abstract: An annuloplasty device is disclosed comprising first and second support rings having a coiled configuration, and respective first and second retention units, the first support ring transitions to the second support ring over a transition section, the transition section is adapted to be arranged at a commissure of the heart valve leaflets, the first and second support rings extend in respective first and second coil planes being essentially perpendicular to the central axis, the transition section bends at least partly along the central axis so that the first coil plane is separated a distance from the second coil plane along the central axis at the transition section.
    Type: Application
    Filed: July 13, 2020
    Publication date: June 30, 2022
    Inventors: Olli Keränen, Hans-Reinhard Zerkowski, Johannes Jung, Jani Virtanen
  • Patent number: 11369471
    Abstract: A medical device for delivering and retrieving a medical implant is disclosed comprising a sheath, a wire having a distal end and being movable in a lumen of the sheath in a longitudinal direction of the sheath. The distal end comprises a locking structure for receiving and interlock with a complementary mating surface of a medical implant, wherein the locking structure comprises a first locking surface aligned in a first radial direction to lock rotational movement of the implant, when received in the locking structure, around the longitudinal direction. The wire comprises a pivotable locking portion having an open and a closed position, the locking portion has a locking structure with a recess locking movement of the implant, when received in the locking structure, in the longitudinal direction, when the locking portion is in the closed position.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: June 28, 2022
    Inventors: Hans-Reinhard Zerkowski, Ger O'Carroll, Mark Pugh