Patents by Inventor Hans Stettler

Hans Stettler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9493512
    Abstract: The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: November 15, 2016
    Assignee: NOVARTIS AG
    Inventors: Murat Acemoglu, Heribert Hellstern, Felix Kollmer, Robert Schreiber, Hans Stettler
  • Publication number: 20160324766
    Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.
    Type: Application
    Filed: December 27, 2013
    Publication date: November 10, 2016
    Inventors: Hans STETTLER, Wim TEUGHELS, Marc QUIRYNEN, Nico BOON
  • Publication number: 20160317414
    Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myoinositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.
    Type: Application
    Filed: December 27, 2013
    Publication date: November 3, 2016
    Applicants: COLGATE-PALMOLIVE COMPANY, KATHOLIEKE UNIVERSITEIT LEUVEN, UNIVERSITEIT GENT
    Inventors: Hans Stettler, Wim TEUGHELS, Marc QUIRYNEN, Nico Boon
  • Patent number: 9278997
    Abstract: The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: March 8, 2016
    Assignee: NOVARTIS AG
    Inventors: Murat Acemoglu, Heribert Hellstern, Felix Kollmer, John Lopez, Robert Schreiber, Christian Sprecher, Hans Stettler
  • Publication number: 20150246897
    Abstract: The invention discloses improved processes for manufacturing a compound, 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-trifluoromethylpyridin-2-amine, its monohydrochloride salt and intermediates thereof.
    Type: Application
    Filed: October 21, 2013
    Publication date: September 3, 2015
    Inventors: Dietmar FLUBACHER, Nicole BIERI, Murat ACEMOGLU, Pascal MICHEL, Rasmus MOSE, Hans STETTLER, Caterina Maria TESTA, Jörg BROZIO, Frank SCHAEFER
  • Publication number: 20150218224
    Abstract: The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Application
    Filed: April 15, 2015
    Publication date: August 6, 2015
    Applicant: NOVARTIS AG
    Inventors: Murat ACEMOGLU, Heribert HELLSTERN, Felix KOLLMER, Robert SCHREIBER, Hans STETTLER
  • Patent number: 9067978
    Abstract: The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: June 30, 2015
    Assignee: NOVARTIS AG
    Inventors: Murat Acemoglu, Heribert Hellstern, Felix Kollmer, Robert Schreiber, Hans Stettler
  • Publication number: 20140100355
    Abstract: The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 10, 2014
    Applicant: NOVARTIS AG
    Inventors: Murat ACEMOGLU, Heribert HELLSTERN, Felix KOLLMER, Robert SCHREIBER, Hans STETTLER
  • Publication number: 20140080995
    Abstract: The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Applicant: NOVARTIS AG
    Inventors: Murat Acemoglu, Heribert Hellstern, Felix Kollmer, John Lopez, Robert Schreiber, Christian Sprecher, Hans Stettler
  • Patent number: 8614289
    Abstract: The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: December 24, 2013
    Assignee: Novartis AG
    Inventors: Murat Acemoglu, Heribert Hellstern, Felix Kollmer, John Lopez, Robert Schreiber, Christian Sprecher, Hans Stettler
  • Publication number: 20120277406
    Abstract: The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Application
    Filed: April 18, 2012
    Publication date: November 1, 2012
    Applicant: NOVARTIS AG
    Inventors: Murat ACEMOGLU, Heribert HELLSTERN, Felix KOLLMER, John LOPEZ, Robert SCHREIBER, Christian SPRECHER, Hans STETTLER
  • Patent number: 4465516
    Abstract: Asymmetrical phosphate esters of formula I ##STR1## in which R is C.sub.1-20 alkyl,R.sub.1 is C.sub.1-20 alkyl,R.sub.2 is hydrogen or methylx is 1-15and M is hydrogen, an alkali metal ion or an equivalent of an alkali earth metal or zinc ionare effective inhibitors of oxidative corrosion of metals in the presence of electrolytes. They may be used alone or in conjunction with further additives, and are preferably dissolved in the electrolyte with which the metal is to come in contact.
    Type: Grant
    Filed: March 10, 1983
    Date of Patent: August 14, 1984
    Assignee: Sandoz Ltd.
    Inventors: Bernard Danner, Hartmut Mau, Hans Stettler
  • Patent number: 4389259
    Abstract: Asymmetrical phosphate esters of formula I ##STR1## in which R is C.sub.1-20 alkyl,R.sub.1 is C.sub.1-20 alkyl,R.sub.2 is hydrogen or methylx is 1-15 andM is hydrogen, an alkali metal ion or an equivalent of an alkali earth metal or zinc ionare effective inhibitors of oxidative corrosion of metals in the presence of electrolytes. They may be used alone or in conjunction with further additives, and are preferably dissolved in the electrolyte with which the metal is to come in contact.
    Type: Grant
    Filed: April 24, 1981
    Date of Patent: June 21, 1983
    Assignee: Sandoz Ltd.
    Inventors: Bernard Danner, Hartmut Mau, Hans Stettler
  • Patent number: 4388205
    Abstract: A liquid phosphate-free wash additive composition comprises an aqueous solution of the following active compounds:(A) 100 parts by weight of a polycarboxylic acid in the salt form(B) 2 to 400 parts by weight of an alkali metal gluconate or glucoheptonate(C) 20 to 700 parts by weight of an alkali metal metasilicate, and(D) 10 to 150 parts by weight of an alkali metal hydroxide.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: June 14, 1983
    Assignee: Sandoz Ltd.
    Inventors: Hans Stettler, Karl Buser, Jean-Pierre Chavannes