Patents by Inventor Hans Tscherter

Hans Tscherter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pipecolic acid-containing peptolides, their preparation and pharmaceutical compositions containing them
    Patent number: 5643869
    Abstract: Pipecolic acid-containing peptolides wherein the peptidic backbone is of at least 9 .alpha.-amino acid residues joined together by peptide bonds, particularly the compounds of formula I ##STR1## wherein the substituents have various significances, are disclosed. They can be prepared by isolation or derivation from an appropriate microorganism strain such as S 42508/F (NRRL 15761).They have interesting pharmacological, e.g. antifungal, chemotherapeutic drug resistance reversing and to some extent immunosuppressant and antiinflammatory properties.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: July 1, 1997
    Assignee: Sandoz Ltd.
    Inventors: Michael Morris Dreyfuss, Gerhard Emmer, Maximilian Grassberger, Klaus Ruedi, Hans Tscherter
  • Cyclosporin peptolides having an .alpha.-hydroxycarboxylic acid at position 8
    Patent number: 5116816
    Abstract: Cyclic peptolides having the structure of a cyclosporin in which one amide linkage is replaced by an ester linkage are obtained by fermentation of fungal strains of the genus Cylindrotrichum Bonorden, or by cyclization of a hydroxy-undecapeptide. The cyclic peptolides have immunosuppressive, anti-inflammatory and anti-parasitic properties.
    Type: Grant
    Filed: June 20, 1988
    Date of Patent: May 26, 1992
    Assignee: Sandoz Ltd.
    Inventors: Michael M. Dreyfuss, Max H. Schreier, Hans Tscherter
  • Ergot cyclic peptide alkaloids having a venotonizing effect, useful for treating orthostatic hypotension
    Patent number: 4804660
    Abstract: 9-thia ergot cyclic peptide alkaloids produced by fermentation or synthetic methods have interesting anti-parkinson and other pharmacological activities.
    Type: Grant
    Filed: May 5, 1987
    Date of Patent: February 14, 1989
    Assignee: Sandoz Ltd.
    Inventors: Hans Kobel, Jean-Jacques Sanglier, Hans Tscherter, Georg Bolliger
  • Antibiotic lactone compound
    Patent number: 4753959
    Abstract: The compound of formula I ##STR1## known as S 39163/F-I which is effective e.g. as an antimicrobial and against herpes viruses.
    Type: Grant
    Filed: December 1, 1986
    Date of Patent: June 28, 1988
    Assignee: Sandoz Ltd.
    Inventors: Hans Tscherter, Hans Hofmann, Roy Ewald, Michael M. Dreyfuss
  • Use of thio isosteres of ergot peptide alkaloids as vasaconstrictors
    Patent number: 4681880
    Abstract: 9-thia ergot cyclic peptide alkaloids produced by fermentation or synthetic methods have interesting anti-parkinson and other pharmacological activities.
    Type: Grant
    Filed: July 2, 1985
    Date of Patent: July 21, 1987
    Assignee: Sandoz Ltd.
    Inventors: Hans Kobel, Jean-Jacques Sanglier, Hans Tscherter, Georg Bolliger
  • 9'Thia-ergots
    Patent number: 4542135
    Abstract: 9-Thia ergot cyclic peptide alkaloids produced by fermentation or synthetic methods have interesting anti-parkinson and other pharmacological activities.
    Type: Grant
    Filed: August 3, 1982
    Date of Patent: September 17, 1985
    Assignee: Sandoz Ltd.
    Inventors: Hans Kobel, Jean-Jacques Sanglier, Hans Tscherter, Georg Bolliger
  • Antibiotic S 31794/F-1
    Patent number: 4173629
    Abstract: This invention provides S 31794/F-1 which is a useful anti-mycotic for combatting Candida albicans infections.
    Type: Grant
    Filed: June 28, 1978
    Date of Patent: November 6, 1979
    Assignee: Sandoz Ltd.
    Inventors: Michael M. Dreyfuss, Hans Tscherter
  • 3-Pyridylamine substituted ergolines
    Patent number: 4004011
    Abstract: This invention provides new compounds of formula I, ##STR1## wherein R is 3-pyridyl or 3-pyridyl mono- or polysubstituted BY LOWER ALKYL, LOWER ALKOXY, LOWER ALKYLTHIO, PHENOXY, HALOGEN, HYDROXY, OR THE GROUP ##STR2## wherein each of R.sub.1 and R.sub.2 is, independently, hydrogen or lower alkyl,Useful as prolactin secretion inhibitors for the treatment of galactorrhea.
    Type: Grant
    Filed: April 9, 1975
    Date of Patent: January 18, 1977
    Assignee: Sandoz Ltd.
    Inventors: Hartmut Hauth, Hans Tscherter