Abstract: An optical device for controlling a light beam includes a beam shaping unit for increasing the uniformity of the spatial intensity profile of the light beam; —a lens system; and —a focusing unit. The lens system comprises a first lens and a second lens, and each of the first lens and the second lens comprises a stepped optical surface formed by active sections and reset sections alternating with each other. The active sections stepwise form a surface profile, which is aspheric, and the stepped optical surface of the first lens faces the stepped optical surface of the second lens.

Abstract: The present application relates to devices and methods for generating light sheets and thin light beams with high Rayleigh lengths by using at least two interconnected meso-optical elements.

Abstract: In a device for the optical imaging of a sample, having at least one light source for excitation light in order to excite a fluorescent dye in a sample, which is held by a sample holder, for spontaneous emission of fluorescent light over a limited period of time in a spatial region having increased resolution, and for de-excitation light in order to de-excite the fluorescent dye again except for a residual zone that is reduced in size relative to the spatial region, wherein light from the sample having wavelengths other than those of the excitation light and of the de-excitation light is assignable to the spontaneous emission of fluorescent light from the residual zone of the spatial region (STED, GSD, etc.), the de-excitation light (3) is arranged to be transmitted in two parallel planes which are separated by a gap (2).

Abstract: The present application relates to devices and methods for generating light sheets and thin light beams with high Rayleigh lengths by using at least two interconnected meso-optical elements.

Abstract: The invention relates to the technical field of the histological preparation of biological tissue comprising a method and means for preparing transparent biological specimens for examination under a light microscope.

Abstract: The invention relates to the technical field of the histological preparation of biological tissue comprising a method and means for preparing transparent biological specimens for examination under a light microscope.

Abstract: In a device for the optical imaging of a sample, having at least one light source for excitation light in order to excite a fluorescent dye in a sample, which is held by a sample holder, for spontaneous emission of fluorescent light over a limited period of time in a spatial region having increased resolution, and for de-excitation light in order to de-excite the fluorescent dye again except for a residual zone that is reduced in size relative to the spatial region, wherein light from the sample having wavelengths other than those of the excitation light and of the de-excitation light is assignable to the spontaneous emission of fluorescent light from the residual zone of the spatial region (STED, GSD, etc.), the de-excitation light (3) is arranged to be transmitted in two parallel planes which are separated by a gap (2).

Abstract: A monitoring device for monitoring an individual under investigation comprises a recording device for recording a neuronal signal from the individual, and a calculating device for calculating a parameter representing a quantitative measure of an anaesthesia or coma condition of the individual and being derived from the neuronal signal, wherein the calculating device is adapted for calculating a complexity parameter representing the quantitative measure of the anaesthesia or coma condition, and the calculating device includes a buffer circuit for storing at least one time series of the neuronal signal and an analysis circuit for subjecting the time series to a recurrence quantification analysis (RQA) providing the complexity parameter. Furthermore, a method includes estimating a parameter representing a quantitative measure of an anaesthesia or coma condition of an individual.