Abstract: A device is for measuring a body parameter for a subject. The device comprises a sensor for measuring the body parameter, a housing element for positioning the sensor on a body part of the subject and an actuator system within the housing element for applying a pressure to the body part. The actuator system comprises two states, a first state based on the actuator system applying a first pressure to a first area of the body part and a second state based on the actuator system applying a second pressure to a second area of the body part. The device also comprises a controller configured to apply the first and second states at different times.

Abstract: The invention refers to a patch cable for connecting a respiratory module (103) to a breathing adapter (101) being, e.g., part of a capnography system. The patch cable (110) comprises a) a module connector (113), b) an adapter connector (114) comprising a light detector, c) a light guide, and d) an electric cable for directing an electric detection signal generated by the light detector from the adapter connector to the module connector. The adapter connector is configured such that an end of the light guide is positioned to provide the light into a gas cavity of the breathing adapter. The adapter connector is adapted such that the light detector detects light provided by the end of the light guide that has interacted with the gas provided in the gas cavity, when the adapter connector is connected to the breathing adapter. This, allows to improve the accuracy of respiratory gas detection.

Abstract: The invention provides a method for obtaining a filtered capnography signal by suppressing a spectral background signal within an optical absorption signal. An optical absorption signal is obtained from a subject across a range of wavelengths, wherein the optical absorption signal represents a proportion of a light signal that is absorbed as the light signal passes through a respiratory air sample undergoing investigation, and wherein the optical absorption signal comprises a spectral background signal. A second harmonic signal is isolated from the optical absorption signal and the period of the spectral background signal is identified. The second harmonic signal is sampled at a central wavelength of the second harmonic signal, wherein the central wavelength represents a maximum Carbon Dioxide absorption, an at an off-center wavelength of the second harmonic signal, wherein the off-center wavelength and the central wavelength are separated by a multiple of the period of the spectral background signal.

Abstract: The present invention provides an optical sensor unit (10) for measuring gas concentration, comprising: sensor means (12, 13) and first thermal insulation means (14, 16) at least partially surrounding said sensor means (12, 13). The sensor means (12,13) includes at least one sensing layer (12) adapted to be irradiated with a predetermined radiation (100), and at least one gas-permeable layer (13) adjacent to one side of the at least one sensing layer (12) and adapted to pass gas, which concentration is to measured, through the gas-permeable layer (13) towards the at least one sensing layer (12). The optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (12), which optical response depends on the gas concentration.

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a first compound other than water; wherein said chemo-optical sensor unit is characterized in that said at least one gas-permeable layer and said at least one sensing layer are permeable to said first compound; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: A fiber assembly (60) for capnography or oxygraphy employing an housing (61), a collimator (64), a retroreflector (67) and a single mode optical fiber (63). Housing (61) including a respiratory gas detection chamber (62). Collimator (64) is rigidly disposed within or detachably attached to housing (61), and retroreflector (67) is rigidly disposed within or detachably attached to housing (61). Collimator (64) and retroreflector (67) are optically aligned within housing (61) across respiratory gas detection chamber (62). Optical fiber (63) is optically aligned with collimator (64) within or external to the housing (61). In operation, optical fiber (63) emits a gas sensing light beam through collimator (64) across respiratory gas detection chamber (62) to retroreflector (67), and optical fiber (63) receives a gas detection light beam reflected from retroreflector (67) across respiratory gas detection chamber (62) through collimator (64) to optical fiber (63).

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a barrier layer which is gas-permeable and impermeable to water and ions; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one gas-permeable sensing layer adapted to be irradiated with a predetermined radiation; and at least a first gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; at least one volatile acid and/or base binding layer in the gas-pathway from the skin to the sensing layer; adapted to pass gas whose concentration is to be measured through the volatile acid and/or base binding layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the chemo-optical sensor unit and the skin and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: The present invention relates to a method for optically determining the concentration of a gas. The method includes using at least two luminescent dyes, the first being in-sensitive to the concentration of a gas with respect to the luminescence response (reference dye) and the second being sensitive to the concentration of a gas with respect to the luminescence response (indicator dye) the dyes show different luminescence decay times so that the resultant phase angle is indicative for the concentration of a gas, wherein the detected luminescent amplitude of the reference dye at a first moment in time is utilized to correct for sensitivity changes after the first moment.

Abstract: There is provided a method of determining at least one parameter value relating to nitric oxide, NO, production in the lower respiratory tract of a subject, the method comprising obtaining a plurality of measurements of NO levels in exhaled air and air flow rate during multiple exhalations of a subject performing tidal breathing; analyzing the plurality of measurements to identify exhalations where the NO produced in the lower respiratory tract dominates the NO contribution from other sources; determining at least one parameter value relating to NO in the lower respiratory tract of the subject from the measurements of NO levels and/or air flow rate obtained during the identified exhalations.

Abstract: For measuring concentrations of fluid-soluble gases with improved drift stability and low production costs, thus dispensing with tedious calibration and/or drift correction routines and re-membraning procedures, a sensor and a system are provided, comprising at least two electrodes, which are covered by sensor fluid at at least one detection site; and an ion-balancing means (50), for example a mixed-bed ion-exchange resin, in contact with the sensor fluid for removing polluting ions.

Abstract: There is provided an apparatus for measuring levels of a specified gas in exhaled breath, the apparatus comprising a photoacoustic sensor for providing a measurement representative of the level of the specified gas in the exhaled air, wherein the photoacoustic sensor comprises a light source that is modulated at a first frequency; a sound speed measurement module for measuring the sound speed of the exhaled breath, wherein the sound speed measurement module operates either at a second frequency that is substantially different to the first frequency or in a pulsed mode; wherein the first frequency of the modulated light source is adjusted during exhalation in accordance with the measured speed of sound of the exhaled breath.

Abstract: An optical sensor unit (10) for measuring a concentration of a gas is provided, comprising at least one sensing layer (122) adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer (121) adjacent to one side of the at least one sensing layer (122) and adapted to pass gas which concentration is to be measured through the gas-permeable layer (121) towards the sensing layer (122); a removable protective layer (150) covering at least the gas-permeable layer (121) and adapted to be removed before use of the optical sensor unit (10), wherein the optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (122), which optical response depends on the concentration of the gas.

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one gas-permeable sensing layer adapted to be irradiated with a predetermined radiation; and at least a first gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; at least one volatile acid and/or base binding layer in the gas-pathway from the skin to the sensing layer; adapted to pass gas whose concentration is to be measured through the volatile acid and/or base binding layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the chemo-optical sensor unit and the skin and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a first compound other than water; wherein said chemo-optical sensor unit is characterized in that said at least one gas-permeable layer and said at least one sensing layer are permeable to said first compound; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: The present invention relates to a method for optically determining the concentration of a gas, using at least two luminescent dyes, the first being in-sensitive to the concentration of a gas with respect to the luminescence response (reference dye) and the second being sensitive to the concentration of a gas with respect to the luminescence response (indicator dye), wherein said dyes show different luminescence decay times so that the resultant phase angle is indicative for the concentration of a gas, characterized in that the detected luminescent amplitude of the reference dye at a first moment in time is utilized to correct for sensitivity changes after said moment. The present invention also relates to a corresponding method for quality assessment of the measurement of an optical sensor for determining the concentration of a gas.

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a barrier layer which is gas- permeable and impermeable to water and ions; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas.

Abstract: The present invention provides an optical sensor unit (10) for measuring gas concentration, comprising: sensor means (12, 13) and first thermal insulation means (14, 16) at least partially surrounding said sensor means (12, 13). The sensor means (12,13) includes at least one sensing layer (12) adapted to be irradiated with a predetermined radiation (100), and at least one gas-permeable layer (13) adjacent to one side of the at least one sensing layer (12) and adapted to pass gas, which concentration is to measured, through the gas-permeable layer (13) towards the at least one sensing layer (12). The optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (12), which optical response depends on the gas concentration.

Abstract: An optical sensor unit (10) for measuring a concentration of a gas is provided, comprising at least one sensing layer (122) adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer (121) adjacent to one side of the at least one sensing layer (122) and adapted to pass gas which concentration is to be measured through the gas-permeable layer (121) towards the sensing layer (122); a removable protective layer (150) covering at least the gas-permeable layer (121) and adapted to be removed before use of the optical sensor unit (10), wherein the optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (122), which optical response depends on the concentration of the gas.

Abstract: For measuring concentrations of fluid-soluble gases with improved drift stability and low production costs, thus dispensing with tedious calibration and/or drift correction routines and re-membraning procedures, a sensor and a system are provided, comprising at least two electrodes, which are covered by sensor fluid at at least one detection site; and an ion-balancing means (50), for example a mixed-bed ion-exchange resin, in contact with the sensor fluid for removing polluting ions.