Abstract: The invention relates to a control system for controlling optical coherence tomography imaging means for imaging a subject, the control system being configured to perform the following steps of an imaging process: receiving (212) a scan data set from the subject being acquired by means of optical coherence tomography, the scan data set including one or several spectra (270), performing (214) data processing on the spectrum or on each of the several spectra of the scan data set (122), including per spectrum: determining (216) a scaling factor (274) for the spectrum (270, 370, 372, 374), scaling (218) a baseline spectrum (272) with a scaling factor (274), and removing (220) the scaled baseline spectrum (276) from the spectrum (270); and providing (224) a baseline corrected image data set of the subject for an image of the subject to be displayed, to an optical coherence tomography imaging system and to a corresponding method.

Abstract: The invention relates to a control system (130) for controlling optical coherence tomography imaging means for imaging a subject (190), the control system being configured to perform the following steps: receiving scan data (122) from the subject (190) being acquired by means of optical coherence tomography, performing data processing on the scan data (122), and obtaining image data (142) for an image (144) of the subject, and the processing system (130) further being configured to adapting, based on a change of a value, the value characterizing an axial position (z) of the subject (190) with respect to the OCT imaging means, between two sets of image data, at least one parameter of the OCT imaging means, to a processing system, to an OCT imaging system (100) and a corresponding method.

Abstract: The invention relates to a processing system for use with optical coherence tomography imaging means for imaging a subject, the processing system being configured to repeatedly perform an image processing process (300), comprising the following steps: receiving (312) a scan data set from the subject (190) being acquired by means of optical coherence tomography, performing (314) data processing on the scan data set, including applying (316) dispersion correction based on a current set (370) of dispersion coefficients, and providing (318) a dispersion corrected image data set of the subject for an image of the subject to be displayed; and the processing system further being configured to repeatedly perform a dispersion coefficient adapting process (340), at least in part, in parallel to the image processing process (300), comprising the following steps: receiving (342) a scan data set from the subject being acquired by means of optical coherence tomography, adapting (344) dispersion coefficients by means of an

Abstract: A system for identifying presence of a conjugate in an image comprising one or more processors and one or more storage devices is provided. The system is configured to acquire spectral data associated with a sample to be imaged. Dispersion coefficients are optimized for acquired spectral data. A corrective phase function is calculated using the optimized dispersion coefficients. A negative corrective phase function is applied to a signal to provide a resulting image. It is determined if the resulting image has degraded signal strength or an enhanced signal strength relative to an original image. A reference arm shift is calculated if it is determined that the resulting image has enhanced signal strength. A position of a reference arm of the system is adjusted based on the calculated reference arm shift to move a conjugate image out of view.

Abstract: A system for optimizing optics is provided. The system is configured to calibrate a position of a reference arm of an interferometric imaging system such that an image of a sample is visible when the sample is positioned at a working distance of an objective lens to provide an initial calibrated position. An image is obtained using the initial calibrated position. Image quality of the obtained image is assessed to determine if the obtained image is a valid image. A path length of the reference arm is adjusted if it is determined that the obtained image is not a valid image. A difference between the calibrated position of the reference arm and the adjusted position of the reference arm is calculated. System elements are adjusted based on the calculated difference such that the ample is visible when the sample is positioned at the working distance at the adjusted position.

Abstract: In accordance with this disclosure, methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography are provided. Synthetic wavelength phase unwrapping can be applied to OCT data and can correctly resolve sample motions that are larger than ?o/2. A method for phase unwrapping of an OCT signal can include acquiring raw OCT signal data, interpolating and processing the OCT signal data to obtain a DC spectrum, comparing the raw OCT signal data to the DC spectrum to generate an interference signal, applying Gaussian windows to the interference signal to generate a two separate signals, extracting phase information from the two signals, and comparing the phase information of the two signals to produce unwrapped phase data. A value of 2? can be added to the phase data if the difference between the phase information of the two signals is less than zero.

Abstract: In accordance with this disclosure, methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography are provided. Synthetic wavelength phase unwrapping can be applied to OCT data and can correctly resolve sample motions that are larger than ?o/2. A method for phase unwrapping of an OCT signal can include acquiring raw OCT signal data, interpolating and processing the OCT signal data to obtain a DC spectrum, comparing the raw OCT signal data to the DC spectrum to generate an interference signal, applying Gaussian windows to the interference signal to generate a two separate signals, extracting phase information from the two signals, and comparing the phase information of the two signals to produce unwrapped phase data. A value of 2? can be added to the phase data if the difference between the phase information of the two signals is less than zero.