Patents by Inventor Hansjorg Kruse

Hansjorg Kruse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4696913
    Abstract: The invention relates to peptides of the formula IR.sup.4 -A.sup.5 -A.sup.6 -A.sup.7 (I)in which R.sup.4 denotes an acyl group, R.sup.5 denotes D-Lys or Lys, A.sup.6 denotes the radical of phenylalanine, N-methylphenylalanine, 4-alkoxyphenylalanine or 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, and R.sup.7 denotes a basic radical, processes for their preparation and their use.
    Type: Grant
    Filed: September 2, 1986
    Date of Patent: September 29, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rolf Geiger, Hermann Gerhards, Hansjorg Kruse
  • Patent number: 4624963
    Abstract: Oxindole compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.1', R.sup.2', R.sup.3', R.sup.4, R.sup.5 and R.sup.6 have the meanings given, and physiologically acceptable salts thereof, for the treatment of epilepsy and their use for the preparation of a medicament for the treatment of epilepsy are described.
    Type: Grant
    Filed: April 9, 1985
    Date of Patent: November 25, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hansjorg Kruse, Heinz Kuch
  • Patent number: 4623715
    Abstract: The invention relates to peptides of the formula IR.sup.4 --A.sup.5 --A.sup.6 --A.sup.7 (I)in which R.sup.4 denotes an acyl group, R.sup.5 denotes D-Lys or Lys, A.sup.6 denotes the radical of phenylalanine, N-methylphenylalanine, 4- alkoxyphenylalanine or 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, and R.sup.7 denotes a basic radical, processes for their preparation and their use.
    Type: Grant
    Filed: October 22, 1984
    Date of Patent: November 18, 1986
    Assignee: Hoechst Aktiengeselleschaft
    Inventors: Rolf Geiger, Hermann Gerhards, Hansjorg Kruse
  • Patent number: 4614739
    Abstract: Oxindole derivatives of the general formula I ##STR1## are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.
    Type: Grant
    Filed: June 18, 1985
    Date of Patent: September 30, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Kuch, Hansjorg Kruse
  • Patent number: 4590273
    Abstract: New isoquinoline derivatives of the general formula ##STR1## and their physiologically acceptable salts, which exert pharmacological actions on the central nervous system and the heart circulation system, a process for the preparation of these compounds, medicaments containing them, and their use as neuroleptic, antihypertonic and antiarrhythmic agents, are described.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: May 20, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Elmar Konz, Franz Hock, Joachim Kaiser, Hansjorg Kruse
  • Patent number: 4547508
    Abstract: 1-Phenylisoquinoline derivatives of the general formula I ##STR1## and a process for their preparation are described. They act on the central nervous system, in particular as antidepressants.
    Type: Grant
    Filed: November 30, 1983
    Date of Patent: October 15, 1985
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Elmar Konz, Hansjorg Kruse
  • Patent number: 4542148
    Abstract: Oxindole derivatives of the general formula I ##STR1## are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.
    Type: Grant
    Filed: April 7, 1982
    Date of Patent: September 17, 1985
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Kuch, Hansjorg Kruse
  • Patent number: 4282223
    Abstract: Isoquinolines of the formula ##STR1## of which representative compounds are such as 3-N-methylpiperazino-1-phenyl-isoquinoline-4-aldehyde, 3-N-methylpiperazino-1-(2-fluorophenyl)-isoquinoline-4-aldehyde, or 3-N-[3-(4-fluoro-benzoyl)-propyl]-piperazino-1-phenyl-isoquinoline-4-aldeh yde and medicaments containing the isoquinolines which are useful as antidepressants.
    Type: Grant
    Filed: September 19, 1979
    Date of Patent: August 4, 1981
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wilhelm Bartmann, Elmar Konz, Hansjorg Kruse, Harry M. Geyer
  • Patent number: 4260763
    Abstract: Isoquinoline-4-aldehydes of the formula ##STR1## in which X denotes bromine or chlorine, R.sub.1 is phenyl optionally mono- or disubstituted by halogen, hydroxy, nitro, amino, or amino substituted by one or two aliphatic, cycloaliphatic or aromatic hydrocarbon radicals having from 2 to 18 carbon atoms, the nitrogen atom possibly being included in a heterocyclic ring, acyl amino, alkyl or alkoxy each having from 1 to 6 carbon atoms, benzoyloxy, or trifluoromethyl, or is pyridyl or thienyl;R.sub.2 is hydrogen, halogen, hydroxy, alkyl or alkoxy having from 1 to 6 carbon atoms, nitro, amino, benzyloxy, methylene dioxy or ethylene dioxy andm is 1 or 2;which are effective in the treatment of spasms and as tranquilizers.
    Type: Grant
    Filed: March 14, 1979
    Date of Patent: April 7, 1981
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wilhelm Bartmann, Elmar Konz, Hansjorg Kruse
  • Patent number: 4053588
    Abstract: Pharmaceutical preparations containing an L-pyroglutamic acid amide, processes for their preparation and methods of treating psychotic diseases with them.
    Type: Grant
    Filed: May 12, 1975
    Date of Patent: October 11, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Hans Wissmann, Hansjorg Kruse, Michel Peterfalvi
  • Patent number: 3931139
    Abstract: The invention relates to tripeptide amides containing pyroglutamine, proline and histidine as amino acids having anti-depressive activity and a process for their manufacture.
    Type: Grant
    Filed: August 22, 1974
    Date of Patent: January 6, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Rolf Geiger, Wolfgang Konig, Hansjorg Kruse, Karl Seeger