Abstract: This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguish itself in that an intracellulary cleavable linker is present between the active substance and the protein. In addition, this invention concerns a process for the preparation of such a conjugate and its use.

Abstract: This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.

Abstract: The present invention relates to conjugates comprising a compound capable of emitting fluorescence, a linker and a protein. The present invention also concerns the preparation of such conjugates as well as their use.

Abstract: This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguishes itself in that an intracellularly cleavable linker is present between the active substance and the protein.

Abstract: A process for the production of an aluminum oxide composition which includes subjecting an aluminoxane with a basic structural element of —Al—O—Al— or a basic oligomeric structural element of —Al—O—Al—O—Al—O—Al— to mild hydrolysis with at least one inert gas moistened below its dew point to produce a composition and subjecting the composition to thermolysis at temperatures from about 300 to about 900° C.

Abstract: An aluminum oxide mass characterized by a specific surface area greater than or equal to 70 m.sup.2 /g and a narrow pore radius distribution, with at least 90% of the pore radii being approximately 0.5 to 2.5 nm, preferably approximately 1.7 to 2.2 nm.

Abstract: The present invention relates pharmaceutical compositions comprising a conjugate of an active substance, a linker and a carrier for the treatment and/or diagnosis of inflammatory diseases. The present invention further relates to methods using such pharmaceutical compositions for treating and diagnosing inflammatory diseases including, but not limited to, infectious diseases, autoimmune diseases, skin diseases, and inflammatory neovascularization.

Abstract: The invention relates to conjugates composed ofa) at least one polyalcohol or a derivatized polyalcohol,b) at least one active agent,c) at least one linker andd) a protein,wherein the polyalcohol(s) or the derivatized polyalcohol(s) are polyalcohols or derivatized polyalcohols which are not recognized by the defense system of an organism as exogenous, and the protein is a protein which can be taken up by the tumor specifically or non-specifically, and is not recognized by the defense system of an organism as exogenous. These conjugates are suitable for, on the one hand, making possible a very sensitive method in nuclear medicine for the diagnosis of tumors and, on the other hand, for example also offering new methods for diagnosing tumors in X-ray diagnosis, computerized tomography, nuclear spin tomography, electron spin resonance spectroscopy or electron microscopy.

Abstract: A liquid fraction and a gas fraction produced during the reprocessing of waste material containing CH compounds by pyrolysis, have a mass ratio approximately equal to 1. Since the liquid fraction is more suitable for further processing than the gas fraction, there is an incentive to augment the liquid fraction at the expense of the gas fraction. In order to achieve this object, the pyrolysis gas is cooled until the benzene and the higher-boiling gaseous constituents of the pyrolysis gas pass into the liquid phase, so that a benzene-containing liquid fraction is produced. A gas mixture containing benzene and toluene is stripped out of the benzene-containing liquid fraction, passed together with the gas fraction at a temperature of 300.degree. to 450.degree. C. over a zeolitic catalyst and then separated by cooling into both a fraction which is liquid at atmospheric pressure and a residual gas fraction.

Abstract: A fluidized bed reactor for the pyrolysis of pieces of rubber or the like, especially old tires the reactor comprising a container at the lower part of which there is discharge device for non-volatile pyrolysis products; gas blowing nozzles arranged in a zone above the discharge device for supplying a fluidizing gas and for producing a fluidized bed from material such as sand or alumina added to the reactor; preferably a heating device, especially one comprising heating tubes extending across the container; a gas outlet disposed in the zone above the fluidized bed; and supply means for conveying pieces of material to be pyrolized to the container; this apparatus is characterized by the fact that the gas blowing nozzles are arranged to direct the gas downwardly, that at least one group of nozzles are arranged in a common horizontal plane, and that the material supply device is such that its dimensions are comparable with the cross-sectional surface of the fluidized bed.