Patents by Inventor Hanson Gifford

Hanson Gifford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250041056
    Abstract: Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient.
    Type: Application
    Filed: October 25, 2024
    Publication date: February 6, 2025
    Applicant: Twelve, Inc.
    Inventors: Mark Deem, Hanson Gifford, III, John Morriss, Matt McLean, Michael Luna
  • Publication number: 20250032284
    Abstract: Delivery systems for delivering an aortic repair device to treat a diseased portion of the aorta of a patient at or near the aortic arch and associated devices and methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include an outer catheter, an inner catheter assembly extending at least partially through the outer catheter, a handle, a tip capture mechanism configured to releasably secure an end portion of the aortic repair device, and a release wire actuatable to release the end portion from the tip capture mechanism. The handle can be actuated to retract the outer catheter relative to the inner catheter assembly to deploy the aortic repair device. The handle can also be actuated to advance a portion of the inner catheter assembly relative to the outer catheter to reorient and position the end portion of the aortic repair device.
    Type: Application
    Filed: July 25, 2024
    Publication date: January 30, 2025
    Inventors: Richard Roy Newhauser, G Ray Martin, Steven Kim, Tony Le, Morgan Jawitz, Simon Nguyen, Hanson Gifford, Brian Tachibana
  • Patent number: 12161552
    Abstract: Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: December 10, 2024
    Assignee: Twelve, Inc.
    Inventors: Mark Deem, Hanson Gifford, III, John Morriss, Matt McLean, Michael Luna
  • Patent number: 11974804
    Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: May 7, 2024
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Denise Zarins, Hanson Gifford, III, Mark E. Deem, Douglas Sutton, Howard R. Levin, Mark Gelfand
  • Publication number: 20230380953
    Abstract: Aortic repair devices and associated systems and methods are disclosed herein. An aortic repair device configured in accordance with embodiments of the present technology can include a base member configured to be implanted in an aorta proximate to a diseased portion of the aorta, such as an aneurysm or dissection. The base member can direct blood flow past the diseased portion of the aorta to perfuse a portion of the aorta distal of the diseased portion. In some embodiments, one or more branch members can be coupled to the base member during the same or a separate intravascular procedure to perfuse one or more branching vessels of the patient's aorta. The branch members can be coupled to the base member via an ex situ or in situ fenestration formed through the base member.
    Type: Application
    Filed: May 26, 2023
    Publication date: November 30, 2023
    Inventors: G Ray Martin, Steven Kim, Hanson Gifford, Katie Miyashiro, Doug Sutton
  • Publication number: 20230330009
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Application
    Filed: June 5, 2023
    Publication date: October 19, 2023
    Inventors: Mark E. Deem, Hanson Gifford
  • Publication number: 20230285274
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Application
    Filed: March 3, 2023
    Publication date: September 14, 2023
    Inventors: Mark E. Deem, Hanson Gifford
  • Publication number: 20230277297
    Abstract: Aortic repair devices and associated systems and methods are disclosed herein. An aortic repair device configured in accordance with embodiments of the present technology can include a base member configured to be implanted in an aorta proximate to a diseased portion of the aorta, such as an aneurysm or dissection. The base member can direct blood flow past the diseased portion of the aorta to perfuse a portion of the aorta distal of the diseased portion and/or various branch vessels. In some embodiments, one or more spanning members or other implants can be coupled (e.g., docked) to the base member during the same or a separate intravascular procedure to provide additional flow paths past the diseased portion.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Inventors: G Ray Martin, Steven Kim, Hanson Gifford, Katie Miyashiro, Doug Sutton, Anuja Harshadray Patel, Richard Roy Newhauser, JR.
  • Patent number: 11679077
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: June 20, 2023
    Assignee: The Foundry, LLC
    Inventors: Mark E. Deem, Hanson Gifford
  • Patent number: 11666526
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: June 6, 2023
    Assignee: The Foundry, LLC
    Inventors: Mark E. Deem, Hanson Gifford
  • Patent number: 11628063
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: April 18, 2023
    Assignee: Twelve, Inc.
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Patent number: 11617648
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: April 4, 2023
    Assignee: Twelve, Inc.
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Patent number: 11576782
    Abstract: Systems, devices and methods for repairing a native heart valve. In one embodiment, a repair device for repairing a native mitral valve having an anterior leaflet and a posterior leaflet between a left atrium and a left ventricle comprises a support having a contracted configuration and an extended configuration, and an appendage, such as a flap or apron extending from the support. In the contracted configuration, the support is sized to be inserted under the posterior leaflet between a wall of the left ventricle and chordae tendineae. In the extended configuration, the support is configured to project anteriorly with respect to a posterior wall of the left ventricle by a distance sufficient to position at least a portion of the posterior leaflet toward the anterior leaflet, and the appendage is configured to extend beyond an edge of the posterior leaflet toward the anterior leaflet.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: February 14, 2023
    Assignee: TWELVE, INC.
    Inventor: Hanson Gifford, III
  • Patent number: 11497603
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: November 15, 2022
    Assignee: Twelve, Inc.
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220346948
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: July 5, 2022
    Publication date: November 3, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220331099
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: July 5, 2022
    Publication date: October 20, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220218473
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220218474
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220218472
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley
  • Publication number: 20220110747
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
    Type: Application
    Filed: December 19, 2021
    Publication date: April 14, 2022
    Inventors: John Morriss, Matt McLean, Maureen Bensing, Jean-Pierre Dueri, Hanson Gifford, III, Katie Miyashiro, David Jerry Scott, David Trask, Kirsten Valley