Abstract: A medical stent includes an expandable structure that is moveable between a collapsed configuration for delivery and an expanded configuration for deployment, the expandable structure in the expanded configuration defining a relaxed diameter. The expandable structure retains its relaxed diameter along portions of the expandable structure that are not constrained by contact with vessel walls after deployment. Portions of the expandable structure that are compressed by contact with vessel walls after deployment are caused to move to a reduced diameter less than the relaxed diameter along portions. The compressed portions of the expandable structure may help prevent plaque from breaking loose. Uncompressed portions of the expandable structure may allow blood flow therethrough.

Abstract: Electro-magnetic devices are provided, having conductive elements and leads of multiple thicknesses. Templates are provided for making electro-magnetic devices, formed by an extrusion process, a skiving process, a swaging process, 3D printing, or a machining process. The multi-thickness electro-magnetic devices may comprise a conductive element having an increased thickness area, and one or more leads having at least one decreased thickness area, having a thickness less than the increased thickness area. An electro-magnetic device may be provided comprising a conductive element having an increased thickness encased in a body formed from a core material, and leads or lead portions connected to the conductive element having a decreased thickness.

Abstract: Antisense oligomer conjugates complementary to a selected target site in the human dystrophin gene to induce exon 53 skipping are described.

Abstract: A method for manufacturing and applying a metal oxide coating for shielding an object from particle radiation includes heating a quantity of a resin of a polyurethane system and mixing a metal oxide with the quantity of the resin of the polyurethane system to form a mixture. The method further includes mixing a quantity of a hardener of the polyurethane system with the mixture to form a metal oxide infused conformal coating (MOICC). The method further includes applying the MOICC to an object to shield the object from particle radiation and curing the MOICC.

Abstract: The disclosure generally pertains to systems and methods for use of a vehicle to conduct a site survey. An example method can include receiving navigation guidance to move a vehicle along a pre-defined path on a property for executing a site survey operation of the property. The site survey operation can include a staking procedure performed by a robotic arm attached to the vehicle, an image capture procedure performed by use of a camera in the vehicle, and/or a subterranean scanning procedure for detecting a buried object. In an example implementation, the staking procedure can include inserting at a first location on the property, a stake having affixed thereon, a barcode label. A barcode scanner can be used to read the barcode label for obtaining information associated with an object present at the first location.

Abstract: The present technology relates to modular valve replacement systems for treating valve-related cardiac disorders. In select embodiments, the modular valve replacement system includes a fixation device and a permanent valve assembly. The fixation device and the permanent valve assembly are delivered separately, enabling use of smaller delivery systems and facilitating less-invasive implant techniques. The fixation device is implanted first and provides a mounting fixture for the subsequently delivered permanent valve assembly. In some embodiments, the permanent valve assembly is at least partially mechanically isolated from the fixation device after the permanent valve assembly is attached to the fixation device. In some embodiments, the fixation device includes a temporary valve assembly that prevents regurgitation until the permanent valve assembly is implanted.

Abstract: Intravascular imaging catheters and methods for making and using intravascular imaging catheters are disclosed. An example intravascular imaging catheter may include an elongate catheter shaft having a distal end region and a proximal region. A guidewire lumen may be defined in the elongate catheter shaft. The distal end region may include an imaging window defined by an open gap in the elongate catheter shaft. An imaging core may be disposed within the elongate catheter shaft. The imaging core may include an imaging device configured to be axially aligned with the imaging window.

Abstract: An implement on a power machine includes at least first and second auxiliary couplers configured to be coupled to a source of hydraulic fluid on the power machine, an hydraulic actuator having a base end coupled to the first auxiliary coupler and a rod end coupled to the second auxiliary coupler and a protection mechanism that is configured to receive hydraulic fluid during normal retraction and extension of the hydraulic actuator. When an unintended external tension force causes the hydraulic actuator to forcibly extend, the protection mechanism is configured to provide hydraulic fluid to the base end of the hydraulic actuator. When an unintended external compression force causes the hydraulic actuator to forcibly retract, the protection mechanism is configured to receive excess hydraulic fluid from the base end.

Abstract: The upper body garments disclosed herein include shoulder straps formed of a woven tubular material flattened into a double-ply fabric. The woven tubular shoulder straps have advantageously high recovery. The upper body garments also include a torso-encircling main body portion with a breast supporting region coupled to a body strap. The body strap is formed of a circular knit, tubular material flattened into double-ply fabric. The woven tubular shoulder straps are coupled to the circular knit, tubular body strap. In some embodiments, the weft yarn of the woven tubular shoulder straps can have different material properties than the warp yarn of the woven tubular shoulder straps. Methods of making the upper body garments are also disclosed herein.

Abstract: Example aspiration catheters and systems including aspiration catheters are disclosed. An example aspiration catheter includes a catheter body having a proximal end region, a distal end region and a lumen extending therein. The aspiration catheter also includes a fluid supply tube extending within the lumen of the catheter body, the fluid supply tube having a distal end region and a distal facing surface. The aspiration catheter also includes a funnel having a proximal end and a distal end, wherein the proximal end is coupled to the distal end region of the catheter body, and wherein the funnel is configured to shift between a collapsed configuration and an expanded configuration.

Abstract: The disclosed garments are designed to address the need for thin, lightweight garments that adequately conceal undergarments and imperfections when in use. Particularly, the garments can conceal the garment's construction, skin imperfections such as cellulite or tattoos, or the color of undergarments despite having a light-colored outer appearance. Methods of making the garments and the concealing material are also disclosed herein.

Abstract: Techniques for generating and executing power consumption profiles for at least one node of a distributed antenna system are described. In executing each power consumption profile, the distributed antenna system can operate with reduced power consumption when advantageous while maintaining appropriate capacity and activity during periods of high activity.

Abstract: Provided herein are peptide-oligomer-conjugates. Also provided herein are methods of treating a central nervous system disorder, a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject 5 peptide-oligomer-conjugates described herein.

Abstract: A single unit in one piece, comprising components for smart glasses, to be positioned in glasses, the single unit comprising at least one cpu, at least one sensor and at least one battery provided on a pcb reaches, when positioned in glasses, at least from a first temple via a frame at least past a first lens positioned closest to the first temple in the frame up to a second lens positioned closest to a second temple, and preferably past also said second lens, and preferably further to said second temple. The single unit comprises at least one hinge, which, when positioned in glasses, will provide at least a hinge between the first temple and the frame, and the single unit is in one piece. A method of making a pair of smart acetate glasses comprising the single unit. A method of exchanging electronics in a single unit comprising electronics.

Abstract: A nanosecond pulser system is disclosed. In some embodiments, the nanosecond pulser system may include a nanosecond pulser having a nanosecond pulser input; a plurality of switches coupled with the nanosecond pulser input; one or more transformers coupled with the plurality of switches; and an output coupled with the one or more transformers and providing a high voltage waveform with a amplitude greater than 2 kV and a frequency greater than 1 kHz based on the nanosecond pulser input. The nanosecond pulser system may also include a control module coupled with the nanosecond pulser input; and an control system coupled with the nanosecond pulser at a point between the transformer and the output, the control system providing waveform data regarding an high voltage waveform produced at the point between the transformer and the output.

Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.

Abstract: A lead assembly includes a thin film body supporting a plurality of electrodes configured to provide electrical stimulation or sensing. The thin film body includes a substrate. A plurality of electrode connection traces is situated on the thin film body and electrically connected to respective ones of the plurality of electrodes. A connection wire is configured to provide stimulation or sensing signals for transmission to the plurality of electrodes. The connection wire extends from a lead and is substantially larger than each of the electrode connection traces. A coupling structure is configured to provide electrical connection between the connection wire and the electrode connection traces.

Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.