Patents by Inventor Hanson S. Gifford, III

Hanson S. Gifford, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10517725
    Abstract: Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: December 31, 2019
    Assignee: Twelve, Inc.
    Inventors: Hanson S. Gifford, III, James I. Fann, John Morriss, Mark Deem, Jeffry J. Grainger
  • Patent number: 10363091
    Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: July 30, 2019
    Assignee: Nuvaira, Inc.
    Inventors: Steven C. Dimmer, Martin L. Mayse, Mark E. Deem, Hanson S. Gifford, III
  • Publication number: 20190223998
    Abstract: Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye.
    Type: Application
    Filed: April 1, 2019
    Publication date: July 25, 2019
    Inventors: Eugene de Juan, JR., Cary J. Reich, Hanson S. Gifford, III, Guy Oren, Matthew Clarke, Jose D. Alejandro
  • Publication number: 20190201191
    Abstract: A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.
    Type: Application
    Filed: July 24, 2018
    Publication date: July 4, 2019
    Inventors: Matt McLean, Hanson S. Gifford, III, James I. Fann, Douglas Sutton
  • Patent number: 10327743
    Abstract: The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. The tissue structures can be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. In one aspect, a structure is deployed in a gutter region of the valve annulus to modify the shape of the valve.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: June 25, 2019
    Assignee: EVALVE, INC.
    Inventors: Frederick G. St. Goar, James I-Lin Fann, Mark E. Deem, Hanson S. Gifford, III, Martin S. Dieck, Brian B. Martin, Sylvia Wenchin Fan, Eric A. Goldfarb, Kent D. Dell, Ferolyn T. Powell
  • Publication number: 20190167188
    Abstract: Systems and methods are disclosed that provide for regular, periodic or continuous monitoring of fluid volume based on direct measurement of an inferior vena cava (IVC) physical dimension using a wireless measurement sensor implanted in the IVC. By basing diagnostic decisions and treatments on changes in an IVC physical dimension, information on patient fluid state is available across the entire euvolemic range of fluid states, thus providing earlier warning of hypervolemia or hypovolemia and enabling the modulation of patient treatments to permit more stable long-term fluid management.
    Type: Application
    Filed: February 9, 2019
    Publication date: June 6, 2019
    Inventors: Hanson S. Gifford, III, Mark E. Deem, Conor M. Hanley, Fiachra M. Sweeney, Jeffry J. Grainger, John R. Britton, Annette Kent
  • Patent number: 10285805
    Abstract: Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: May 14, 2019
    Assignee: ForSight Labs, LLC
    Inventors: Eugene de Juan, Jr., Cary J. Reich, Hanson S. Gifford, III, Guy Oren, Matthew Clarke, Jose D. Alejandro
  • Publication number: 20190083768
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Application
    Filed: July 16, 2018
    Publication date: March 21, 2019
    Inventors: Mark E. Deem, Hanson S. Gifford, III
  • Publication number: 20190076033
    Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.
    Type: Application
    Filed: October 31, 2018
    Publication date: March 14, 2019
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Shriram Raghunathan, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley
  • Patent number: 10206741
    Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: February 19, 2019
    Assignee: Nuvaira, Inc.
    Inventors: Steven C. Dimmer, Martin L. Mayse, Mark E. Deem, Hanson S. Gifford, III
  • Publication number: 20190029639
    Abstract: Implantable devices for continuously monitoring vascular lumen dimensions, in particular in the inferior vena cava (IVC) for determining heart failure status of a patient. Related therapy systems as well as monitoring and therapy methods are also disclosed. Devices include active or passive marker elements placed in contact with, adhered to or injected into the vessel wall to generate or reflect signals from which lumen diameter may be determined. Disclosed devices may be fully implantable and self-contained including capabilities for wirelessly communication monitored parameters.
    Type: Application
    Filed: October 2, 2018
    Publication date: January 31, 2019
    Inventors: Hanson S. Gifford, III, Mark E. Deem, Douglas S. Sutton, Vijaykumar Rajasekhar
  • Publication number: 20180292403
    Abstract: A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
    Type: Application
    Filed: November 8, 2017
    Publication date: October 11, 2018
    Inventors: Eugene de Juan, JR., Yair Alster, Steven M. Chamow, Kathleen C. Farinas, Hanson S. Gifford, III, K. Angela Macfarlane, Cary J. Reich, Michael Barrett, Randolph E. Campbell, Robert George, Douglas Sutton
  • Publication number: 20180220992
    Abstract: Catheter-based devices and methods for continuously monitoring vascular lumen dimensions, in particular in the inferior vena cava (IVC) for determining heart failure and/or fluid status of a patient. Related therapy systems and methods for integrated monitoring and therapy are also disclosed.
    Type: Application
    Filed: August 3, 2016
    Publication date: August 9, 2018
    Inventors: Hanson S. Gifford, III, Mark E. Deem, Martin L. Mayse, Vijaykumar Rajasekhar
  • Publication number: 20180206887
    Abstract: Pathology of the human knee can arise from excessive and/or uneven loading of regions within the joint. Methods and apparatus are disclosed that enable displacement of soft tissue around the knee, without displacing or severing bone thereby altering the mechanical load distribution within the joint in a less invasive manner than previous techniques.
    Type: Application
    Filed: March 21, 2018
    Publication date: July 26, 2018
    Inventors: Vivek Shenoy, Hanson S. Gifford, III, Mark Deem
  • Patent number: 10022529
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 17, 2018
    Assignee: The Foundry, LLC
    Inventors: Mark E. Deem, Hanson S. Gifford, III
  • Publication number: 20180177486
    Abstract: Implantable devices for continuously monitoring vascular lumen dimensions, in particular in the inferior vena cava (IVC) for determining heart failure status of a patient. Related therapy systems as well as monitoring and therapy methods are also disclosed. Devices include active or passive marker elements placed in contact with, adhered to or injected into the vessel wall to generate or reflect signals from which lumen diameter may be determined. Disclosed devices may be fully implantable and self-contained including capabilities for wirelessly communication monitored parameters.
    Type: Application
    Filed: February 12, 2016
    Publication date: June 28, 2018
    Inventors: Hanson S. Gifford, III, Mark E. Deem, John Morriss, Douglas S. Sutton, Jeffry J. Grainger, Vijaykumar Rajasekhar
  • Publication number: 20180092775
    Abstract: Methods and devices are adapted for implanting into the eye. An incision is formed in the cornea of the eye and a shunt is inserted through the incision into the anterior chamber of the eye. The shunt includes a fluid passageway. The shunt is passed along a pathway from the anterior chamber through the scleral spur of the eye into the suprachoroidal space and positioned in a first position such that a first portion of the fluid passageway communicates with the anterior chamber and a second portion of the fluid passageway communicates with the suprachoroidal space to provide a fluid passageway between the suprachoroidal space and the anterior chamber.
    Type: Application
    Filed: September 20, 2017
    Publication date: April 5, 2018
    Inventors: Eugene de Juan, JR., Stephen Boyd, Mark E. Deem, Hanson S. Gifford, III, Dan Rosenman
  • Patent number: 9931136
    Abstract: Pathology of the human knee can arise from excessive and/or uneven loading of regions within the joint. Methods and apparatus are disclosed that enable displacement of soft tissue around the knee, without displacing or severing bone thereby altering the mechanical load distribution within the joint in a less invasive manner than previous techniques.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: April 3, 2018
    Assignee: The Foundry, LLC
    Inventors: Vivek Shenoy, Hanson S. Gifford, III, Mark Deem
  • Publication number: 20180055541
    Abstract: Pathologies of joints arising from improper force distributions are addressed by displacement of targeted connective and muscle tissues surrounding the joint in order to realign force vectors and alter moment arms loading the joint.
    Type: Application
    Filed: October 23, 2017
    Publication date: March 1, 2018
    Inventors: Vivek Shenoy, Mark Deem, Hanson S. Gifford, III
  • Publication number: 20180042668
    Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.
    Type: Application
    Filed: May 30, 2017
    Publication date: February 15, 2018
    Inventors: Steven C. Dimmer, Martin L. Mayse, Mark E. Deem, Hanson S. Gifford, III