Patents by Inventor Hanson S. Gifford, III

Hanson S. Gifford, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11224570
    Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.
    Type: Grant
    Filed: February 15, 2021
    Date of Patent: January 18, 2022
    Assignee: Foundry Therapeutics, Inc.
    Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
  • Publication number: 20220000621
    Abstract: Leaflet extension devices for cardiac valve leaflets and methods of treating cardiac valve leaflets. Several embodiments are devices for resolving regurgitation in a cardiac valve comprising an expandable member and a cover. The expandable member has a stabilizing portion, a fixation member in opposition to the stabilizing portion, and a coaptation portion between the stabilizing portion and the expandable member. The stabilizing portion and the fixation member clamps the first native leaflet between the stabilizing portion and the fixation member. The coaptation portion projects from the stabilizing portion and the fixation member inwardly with respect to a first native leaflet of a cardiac valve such that the coaptation portion functionally extends the first native leaflet. The cover is attached to at least the coaptation portion of the expandable member.
    Type: Application
    Filed: November 14, 2018
    Publication date: January 6, 2022
    Inventors: Hanson S. Gifford, III, Matt McLean, Gaurav Krishnamurthy
  • Publication number: 20210401306
    Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley, Shriram Raghunathan, Sean Quinlan
  • Publication number: 20210401305
    Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley
  • Patent number: 11206992
    Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: December 28, 2021
    Assignee: Foundry Innovation & Research 1, Ltd.
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Shriram Raghunathan, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley, Sean Quinlan
  • Patent number: 11202754
    Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: December 21, 2021
    Assignee: Foundry Therapeutics, Inc.
    Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
  • Publication number: 20210369334
    Abstract: Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other conditions in target neural fibers. In some embodiments, the ITEV PEF system comprises an intravascular catheter having one or more electrodes configured for intra-to-extravascular placement across a wall of patient's vessel into proximity with target neural fibers. With the electrode(s) passing from an intravascular position to an extravascular position prior to delivery of the PEF, a magnitude of applied voltage or energy delivered via the electrode(s) and necessary to achieve desired neuromodulation may be reduced relative to an intravascular PEF system having one or more electrodes positioned solely intravascularly.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 2, 2021
    Inventors: Denise Zarins, Benjamin J. Clark, Nicolas Zadno, Hanson S. Gifford, III, Erik Thai
  • Publication number: 20210353532
    Abstract: The present technology relates to depot assemblies for the controlled, sustained release of a therapeutic agent. The assembly can include a depot having a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days. The assembly further includes a fixation portion coupled to the depot and configured to facilitate attachment of the depot assembly to tissue at or adjacent to the treatment site.
    Type: Application
    Filed: August 27, 2019
    Publication date: November 18, 2021
    Inventors: Karun D. Naga, Hanson S. Gifford, III, Jackie Joe Hancock, Stephen W. Boyd, John Morriss, Patrick H. Ruane, Michael Feldstein, Darren Doud, Mark Deem, Koon Kiat Teu, Daniel Boon Lim Seet, Wei Li Lee, Honglei Wang
  • Publication number: 20210338419
    Abstract: The present technology relates to modular valve replacement systems for treating valve-related cardiac disorders. In select embodiments, the modular valve replacement system includes a fixation device and a permanent valve assembly. The fixation device and the permanent valve assembly are delivered separately, enabling use of smaller delivery systems and facilitating less-invasive implant techniques. The fixation device is implanted first and provides a mounting fixture for the subsequently delivered permanent valve assembly. In some embodiments, the permanent valve assembly is at least partially mechanically isolated from the fixation device after the permanent valve assembly is attached to the fixation device. In some embodiments, the fixation device includes a temporary valve assembly that prevents regurgitation until the permanent valve assembly is implanted.
    Type: Application
    Filed: October 7, 2019
    Publication date: November 4, 2021
    Inventors: Hanson S. Gifford, III, James I. Fann, Matthew McClean, Gaurav Krishnamurthy, Vrad Levering, Neil Zimmerman
  • Publication number: 20210308433
    Abstract: Devices, systems, and methods for treating a blood flow passage are discloses herein. In one example, a treatment device includes an expandable element configured to be positioned within the passage and a reinforcing element. The expandable element may have an expanded configuration in which the expandable element defines a lumen therethrough. The reinforcing element may be positioned within the lumen of the expandable element. The reinforcing element may be coupled to the expandable element such that expansion of the expandable element causes the reinforcing element to radially expand, thereby creating a perfusion lumen through the device.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Inventors: Hanson S. Gifford, III, Edward DeWitt Gifford, Vrad W. Levering
  • Publication number: 20210307767
    Abstract: Systems and methods are provided for removal of clot material from a treatment site in a blood vessel, particularly in venous vasculature. A treatment device (101) can include a core member (115) having a distal portion (109) and an inner coil (111) surrounding the distal portion of the core member. A helical outer member (113) surrounds at least a portion of the inner coil, and a sheet of flexible material (117) extends between the inner coil and the helical outer member, such that the sheet extends helically around the inner coil to provide a surface for clot engagement at the treatment site.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Inventors: Hanson S. Gifford, III, Edward DeWitt Gifford
  • Publication number: 20210298826
    Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
    Type: Application
    Filed: June 14, 2021
    Publication date: September 30, 2021
    Inventors: Mark E. Deem, Hanson S. Gifford, III, Denise Zarins, Douglas Sutton, Erik Thai, Mark Gelfand, Howard R. Levin
  • Publication number: 20210244381
    Abstract: Patient fluid management systems, particularly for use in treating patients at various stages of heart failure, are disclosed. Disclosed systems employ vascular dimension monitoring sensors to provide accurate, early, real-time estimation of circulating blood volume as an input metric to the system control, allowing for more accurate modulation of treatment based on the patient's current fluid volume state.
    Type: Application
    Filed: April 30, 2021
    Publication date: August 12, 2021
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Annette Kent, Conor M. Hanley
  • Patent number: 11083572
    Abstract: A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: August 10, 2021
    Assignee: Half Moon Medical, Inc.
    Inventors: Matt McLean, Hanson S. Gifford, III, James I. Fann, Douglas Sutton
  • Publication number: 20210186868
    Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.
    Type: Application
    Filed: February 15, 2021
    Publication date: June 24, 2021
    Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
  • Patent number: 11039813
    Abstract: Catheter-based devices and methods for continuously monitoring vascular lumen dimensions, in particular in the inferior vena cava (IVC) for determining heart failure and/or fluid status of a patient. Related therapy systems and methods for integrated monitoring and therapy are also disclosed.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: June 22, 2021
    Assignee: Foundry Innovation & Research 1, Ltd.
    Inventors: Hanson S. Gifford, III, Mark E. Deem, Martin L. Mayse, Vijaykumar Rajasekhar
  • Publication number: 20210145405
    Abstract: Methods for patient self-monitoring of vascular lumen dimensions, in particular in the inferior vena cava (IVC) for determining heart failure status of a patient. Related therapy systems as well as monitoring and therapy methods are also disclosed.
    Type: Application
    Filed: January 29, 2021
    Publication date: May 20, 2021
    Inventors: Hanson S. Gifford, III, Mark E. Deem, Jeffry J. Grainger
  • Publication number: 20210128357
    Abstract: Methods and devices are adapted for implanting into the eye. An incision is formed in the cornea of the eye and a shunt is inserted through the incision into the anterior chamber of the eye. The shunt includes a fluid passageway. The shunt is passed along a pathway from the anterior chamber through the scleral spur of the eye into the suprachoroidal space and positioned in a first position such that a first portion of the fluid passageway communicates with the anterior chamber and a second portion of the fluid passageway communicates with the suprachoroidal space to provide a fluid passageway between the suprachoroidal space and the anterior chamber.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 6, 2021
    Inventors: Eugene de Juan, JR., Stephen Boyd, Mark E. Deem, Hanson S. Gifford, III, Dan Rosenman
  • Publication number: 20210085462
    Abstract: Cardiac valve repair devices with coaptation members and multiple clip mechanisms and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an optional fixation member configured to engage tissue within a left atrium proximate to a native mitral valve, a coaptation member depending from the fixation member, and a plurality of clip mechanisms extending from a downstream portion of the coaptation member. The coaptation member can be positioned between the native leaflets and at least partially fill a space between the native leaflets. A first clip mechanism can engage a first portion of one of the native leaflets, and a second clip mechanism can engage another portion of the same native leaflet or an opposing native leaflet.
    Type: Application
    Filed: September 21, 2020
    Publication date: March 25, 2021
    Inventors: Hanson S. Gifford, III, Ben F. Brian, III, Matthew McLean, Gaurav Krishnamurthy, Neil Zimmerman, James I. Fann, Katie Miyashiro
  • Patent number: 10953170
    Abstract: Apparatus and methods for providing intrabronchial delivery of a treatment fluid to control the effects of a bronchial condition. The apparatus can include a shaft having proximal and distal ends and a fluid injection assembly disposed on the distal end. The fluid injection assembly can be a deployable needle assembly, a rotating needle assembly, a needle-less injection assembly, or a nebulizer assembly.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: March 23, 2021
    Assignee: Nuvaira, Inc.
    Inventors: Mark E. Deem, Hanson S. Gifford, III