Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.

Abstract: Disclosed herein is a computer-implemented method of processing a query using a columnstore comprising a plurality of segments, the method comprising: receiving a query comprising a parameter; determining a key corresponding to the parameter; identifying a mapping structure, from a plurality of mapping structures, relating to said key, wherein each mapping structure corresponds to a respective segment of the columnstore; interrogating the identified mapping structure to determine a value corresponding to the key, wherein the value identifies an entry of an index table of a plurality of index tables that corresponds to the respective segment, wherein the entry of the index table identifies a row of the respective segment of the columnstore relating to the parameter; and retrieving data relating to the parameter from a data source based on data stored in the entry of the index table.

Abstract: Methods and systems for searching directory access groups are disclosed. A set of groups associated with a logon user is determined. The set of groups is partitioned into one or more disjoint subsets, wherein each of the disjoint subsets is represented by a data representation including a root node and one or more intermediate nodes. For each of the disjoint subsets, the disjoint subset is path compressed to flatten a structure of the data representation representing the disjoint subset. The data representation is cached to a database cache.

Abstract: Methods and systems for searching directory access groups are disclosed. A set of groups associated with a logon user is determined. The set of groups is partitioned into one or more disjoint subsets, wherein each of the disjoint subsets is represented by a data representation including a root node and one or more intermediate nodes. For each of the disjoint subsets, the disjoint subset is path compressed to flatten a structure of the data representation representing the disjoint subset. The data representation is cached to a database cache.