Patents by Inventor Hanxiao Qin

Hanxiao Qin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALLOGENEIC CAR-T CELL, PREPARATION THEREFOR, AND APPLICATION THEREOF
    Publication number: 20220340639
    Abstract: Provided are allogeneic CAR-T cells prepared by expressing related functional proteins in T cells and regulating HLA class I molecules on the cell surface. Also provided is the use of the allogeneic CAR-T cells.
    Type: Application
    Filed: April 22, 2020
    Publication date: October 27, 2022
    Inventors: Jun Li, Pengchao Zhang, Zhao Xu, Ling He, Weikang Liu, Yuchen Jiang, Hanxiao Qin, Yu Xia
  • ALLOGENEIC CAR-T CELL, PREPARATION THEREFOR, AND APPLICATION THEREOF
    Publication number: 20220313736
    Abstract: Provided is an engineered T cell. The expression level of an HLA class I molecule on the surface of the T cell is down-regulated to 10-50% of that of a non-engineered T cell. The expression of the T cell down-regulates a functional protein of the HLA class I molecule. The functional protein down-regulates at least one of HLA-A, HLA-B, and HLA-E molecules of the HLA class I molecule. The T cell may be an allogeneic CAR-T cell. Also provided is an application of the T cell or the allogeneic CAR-T cell.
    Type: Application
    Filed: April 22, 2020
    Publication date: October 6, 2022
    Inventors: Jun Li, Pengchao Zhang, Zhao Xu, Ling He, Weikang Liu, Yuchen Jiang, Hanxiao Qin, Yu Xia